Thierry Galli 🧫🧬🔬🎸🔊 🇪🇺🇫🇷
@tgalli.bsky.social
Cell Biologist, Neuroscientist, Guitarist. #VAMP7 #Sybl1 #TIVAMP #Longin aficionado. Only personal views.
Just Published! onlinelibrary.wiley.com/doi/10.1111/... @labsoap.bsky.social
Syntaxin 12 Sustains Endosomal‐Lysosomal Homeostasis and Survival in Glioblastoma Stem‐Like Cells
Syntaxin12 maintains endolysosomal trafficking and lysosomal homeostasis in glioblastoma cells. Syntaxin12 depletion disrupts lysosomal organization, impairs endolysosomal progression and mTOR-lysoso...
onlinelibrary.wiley.com
Just Published ! onlinelibrary.wiley.com/doi/10.1111/...
The Power of Nup85: Controlling Molecular Traffic and Cellular Fate
Nup85 is a protein that plays a critical role in nucleocytoplasmic transport, facilitating the movement of macromolecules, including proteins and RNA, between the nucleus and the cytoplasm. Additiona...
onlinelibrary.wiley.com
🎉 50 years of #Clathrin! The second article in Traffic's Special Issue is now online. #CellBiology #MembraneTrafficking #Endocytosis #TrafficJournal Edited by Emanuele Cocucci, Jeanne Stachowiak & Margaret Robinson. onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
#Traffic is proud to inaugurate its #TrafficLights commentary section in a #JournalClub report format... it starts now with @JulieGavard onlinelibrary.wiley.com/doi/10.1111/...
Traffic Light Commentary—Src in the Upside Down: A Kinase Turned Inside Out
Just as Antelope Canyon transforms familiar rock into an unexpected hidden landscape, the topological inversion of Src reveals an unforeseen extracellular facet of kinase signaling in cancer. Antelop...
onlinelibrary.wiley.com
Two more reviews have just been published! #Clathrin is 2026 #Traffic superstar! onlinelibrary.wiley.com/doi/10.1111/... onlinelibrary.wiley.com/doi/10.1111/...
Integrating Lateral Super‐Resolution and Axial Progression Reveals Distinct Clathrin Pit Formation Pathways
Variable-angle total internal reflection fluorescence structured illumination microscopy (vaTIRF-SIM) links nanoscale lateral organization with axial progression during clathrin-mediated endocytosis....
onlinelibrary.wiley.com
Traffic@traffic-journal.bsky.social · 2mo ago🎉 50 years of #Clathrin! The second article in Traffic's Special Issue is now online. #CellBiology #MembraneTrafficking #Endocytosis #TrafficJournal Edited by Emanuele Cocucci, Jeanne Stachowiak & Margaret Robinson. onlinelibrary.wiley.com/doi/10.1111/...
Just Published ! onlinelibrary.wiley.com/doi/10.1111/...
The Lack of a COPII Cargo Receptor Erv14 Impacts Physiological Functions of the Vacuole in Saccharomyces cerevisiae
Loss of the cargo receptor Erv14 in Saccharomyces cerevisiae results in sensitivity to calcium, zinc, neutral extracellular pH, and elevated temperature. Furthermore, cells deleted in the ERV14 exhib...
onlinelibrary.wiley.com
Just Published ! onlinelibrary.wiley.com/doi/10.1111/...
A Toolbox for Quantifying Nuclear and Nucleolar Protein Accumulation Using NLS and NoLS Fusion Reporters
Fluorescent proteins fused with nuclear (NLS) or nucleolar (NoLS) localization signals are commonly used for live assessment of protein accumulation in the nucleus and nucleolus. We present a standar...
onlinelibrary.wiley.com
Just Published ! onlinelibrary.wiley.com/doi/10.1111/...
Unraveling the Dynamics of Oxytocin in Hypothalamic Neurons
Oxytocin (OT) plays an important role in regulating social behavior, and dysregulation of the oxytocinergic system leads to social impairments, such as autism spectrum disorder. Central OT release is...
onlinelibrary.wiley.com
Just Published ! onlinelibrary.wiley.com/doi/10.1111/...
KIF5B and Dynein‐Dependent Golgi Organization: Role in Adhesion‐Dependent Microtubule Acetylation
KIF5B and dynein regulate Golgi organization and localization- Role in regulating MT acetylation: In control (CNT) cells, active Arf1 facilitates the recruitment of KIF5B and dynein to the Golgi, mai....
onlinelibrary.wiley.com
Just Published ! onlinelibrary.wiley.com/doi/10.1111/...
Protein Kinase D Regulates Kinesin‐Mediated VEGFR2 Trafficking and Influences Retinal Endothelial Permeability
Upon VEGF binding, VEGFR2 is autophosphorylated and recruits downstream signaling molecules, leading to protein kinase D (PKD)1 phosphorylation. We found that PKD1 phosphorylates KIF13B, a kinesin-3 ...
onlinelibrary.wiley.com
fantastic venue, fantastic program, just apply and spread the word 🧠 🌊💺
Eric Chevet@ericchevet.bsky.social · 5mo ago🗣️You can NOW (at last) register for the Brain Tumor Meeting By The Sea which will be held in #StMalo from March 23 to March 25 here btmbts26.sciencesconf.org 🤩The keynote speakers are @annagolebiewska.bsky.social, #David_Castel and @benjaminwerner.bsky.social poke @labsoap.bsky.social
🗣️You can NOW (at last) register for the Brain Tumor Meeting By The Sea which will be held in #StMalo from March 23 to March 25 here btmbts26.sciencesconf.org 🤩The keynote speakers are @annagolebiewska.bsky.social, #David_Castel and @benjaminwerner.bsky.social poke @labsoap.bsky.social
Kudos to the whole team and @tgalli.bsky.social -- 🙏 for allowing us to collaborate on this super exciting story -- I would also add #stress #organelles -- #ER_literature #proteostasis
Thierry Galli 🧫🧬🔬🎸🔊 🇪🇺🇫🇷@tgalli.bsky.social · 5mo ago#VAMP7-dependent late endosomal #secretion of #ER and #mitochondrial proteins impacts the #tumor #microenvironment and #macrophage engagement www.nature.com/articles/s41...
#VAMP7-dependent late endosomal #secretion of #ER and #mitochondrial proteins impacts the #tumor #microenvironment and #macrophage engagement www.nature.com/articles/s41...
VAMP7-dependent late endosomal secretion of ER and mitochondrial proteins impacts the tumor microenvironment and macrophage engagement - Nature Communications
The SNARE VAMP7 is essential for an unconventional secretory pathway based on late endosomal secretion. Here the authors show that this secretion functions as an organelle quality-control and stress-c...
nature.com
The registration deadline for this wonderful meeting is approaching! Be sure to reserve your spot before March 10!
Matthew Taliaferro@jmtali.bsky.social · 8mo agoAnnouncing the 2026 edition of the EMBO workshop on RNA localization and local translation! This meeting will be held June 30 - July 4 near Porto, Portugal. Come for exciting updates in the field from both established investigators and trainees. See the link below for details!
Cette image ne vous rappelle-t-elle pas les boules de Noël sur votre sapin ? 😍 C'est avec cette jolie image que l'Inserm vous souhaite un joyeux Noël !🎄
Announcing the #China-#France Joint #Conference on #Neurodegeneration and #Secretion, to be held on March 10-13, 2026, in #Shenzhen. Inserm #ShenzhenBayLaboratory #ambassadedefranceenchine #institutfrançais lnkd.in/eygqBe8H lnkd.in/ee88be-F lnkd.in/e__7WYTJ
Entering the USA no more… sorry for all American scientists and friends…
Ron Filipkowski@ronfilipkowski.bsky.social · 8mo agoThe Trump admin sanctions several European officials today after Elon Musk was fined for several violations of their Digital Services Act.
Announcing the #China-#France Joint #Conference on #Neurodegeneration and #Secretion, to be held on March 10-13, 2026, in #Shenzhen. Inserm #ShenzhenBayLaboratory #ambassadedefranceenchine #institutfrançais lnkd.in/eygqBe8H lnkd.in/ee88be-F lnkd.in/e__7WYTJ
Just Published! Spatiotemporal Analysis of Glucagon Secretory Granule Dynamics - Ghignoli - 2025 - Traffic - Wiley Online Library onlinelibrary.wiley.com/doi/abs/10.1...
onlinelibrary.wiley.com
Just Published ! Virion Associated Importin Subunit Beta‐1 Augments Nuclear Import of HIV‐1 Pre‐Integration Complex - Yandrapally - 2025 - Traffic - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Just Published ! onlinelibrary.wiley.com/doi/10.1111/...
Beyond the Secretory Pathway: New Insights Into Protein Release
While proteins bearing N-terminal signal or leader sequences are secreted via the ER-Golgi-plasma membrane axis of the conventional secretion pathway, many cytosolic proteins lacking signaling sequen...
onlinelibrary.wiley.com
Just Published !! onlinelibrary.wiley.com/doi/10.1111/...
Copper Homeostasis at the Crossroads of Cellular Metabolism, Epigenetic Regulation and Protein Trafficking
Copper homeostasis is maintained in the cell by epigenetic regulation, and various metabolic processes. Regulated copper homeostasis balances normal protein trafficking, amino acid metabolism, etc., ...
onlinelibrary.wiley.com
The Ecological Transition Conference @ipnp.bsky.social , organized by F Koukouli, MC Angulo, and D Zala, was a great success! Thank you to Inserm and IPNP for their support, to speakers M Thepin, TB Duong, and HSalmon, and to all participants for the engaging talks! @inserm.fr
Kickoff of IPNP's retreat! A great opportunity for all the teams to meet, share knowledge, develop collaborations and .... enjoy!
Huge congrats to the team of project "PatCorg" for the prestigious ERC Synergy grant dedicated to studying organoids to uncover mechanisms underlying cortical development: A Pierani (@ipnp.bsky.social), S Nedelec (Institut Monod), S Descroix and B Sorre (Institut Curie), and A Baffet (Inst Curie).
