Please share! What companies have folks successfully worked with to generate custom antibodies? Rough cost? We've been burned once before and want to try a different company this time around.

Please share! What companies have folks successfully worked with to generate custom antibodies? Rough cost? We've been burned once before and want to try a different company this time around.

@acs.org's new website doesn't show article stats any more like views and citations. they don't even the most read list anymore. I liked to track how are articles were doing. 😮‍💨 nvm that the format also just looks weird now too. huge bummer.

‘Science: A New Golden Age’ report calls for shifting billions from universities to tech companies www.statnews.com/2026/07/24/s...

White House offers its science blueprint: More AI, less life sciences

The Trump administration released its blueprint for U.S. science, calling for shifting hundreds of billions of research dollars from universities to industry.

statnews.com

Annnnnd my RPPR was just flagged for reporting publications with foreign collaborators. What is happening?

Jeffrey Brainard@jeffreybrainard.bsky.social · 3mo ago

U.S. researchers who coauthor research papers with scientists affiliated with foreign institutions are drawing fresh scrutiny from NIH, NASA. #scientificpublishing @science.org www.science.org/content/arti...

Annnnnd my RPPR was just flagged for reporting publications with foreign collaborators. What is happening?

Jeffrey Brainard@jeffreybrainard.bsky.social · 3mo ago

U.S. researchers who coauthor research papers with scientists affiliated with foreign institutions are drawing fresh scrutiny from NIH, NASA. #scientificpublishing @science.org www.science.org/content/arti...

Excited to see this collaboration now in print. Dye chemistry meets AI-designed proteins. Three small, orthogonal tags; lifetime modulation; split versions. Request the free dyes at dyes.janelia.org www.science.org/doi/10.1126/...

De novo design of orthogonal far-red, orange, and green fluorophore-binding proteins for multiplexed imaging

Fluorescent proteins and small-molecule dyes offer complementary advantages for biological imaging: proteins are amenable to genetic tagging, whereas dyes provide superior brightness and photostabilit...

science.org

this one is some kind of intense inside joke must be

In Preparation@inprep.bsky.social · 3w ago

Rest of World@restofworld.org · 4w ago

For $7 an hour, virtual assistants in the Philippines are using AI to write LinkedIn posts and comments on behalf of Western executives, fueling a "thought leadership" content mill https://restofworld.org/2026/virtual-assistant-linkedin-engagement/?utm_campaign=row-social

@sufs-paris-rp.bsky.social has an easy to use web portal for submitting comments in response to proposed OMB rule change as well as contacting your representatives: fight2win.standupforscience.net?utm_source=o...

Stand up for Science

Stand up for Science

fight2win.standupforscience.net

Evotip flow through for gDNA. Nice! But made me wonder about new hotness in other methods: what happened to nano pots where they put a tissue on the spots to do multi omics, or floating cells from @gaolab.bsky.social? I’m not in this field and this is a lazy post. (👀 @proteomicsnews.bsky.social)

Mann Lab@mannlab.bsky.social · 4w ago

New preprint: Cell-type-resolved spatial proteogenomics, matched genome AND proteome of the same cells. The trick: the flowthrough we normally discard after loading peptides onto an Evotip contains genomic DNA at 85–95% yield. One tip, two molecular layers. www.biorxiv.org/content/10.6...

The qed score cited above is one based on AI. SolvingForScience by contrast have taken a human expert approach. Both claim to determine quality better than the current proxies www.biorxiv.org/content/10.1... 3/n

Discovery Stack Pilot: Feasibility and Outcomes of a Scientist-Designed Peer Review Model Separating Quality and Impact

Peer review serves as the cornerstone of scientific quality control. Yet, the current journal-centric system is hindered by long timelines, high publication costs, inconsistent review quality, systemi...

biorxiv.org

EXCLUSIVE: Eli Lilly gave compassionate use access to retatrutide, their unapproved powerful obesity drug, to a 79-year-old man in April. The application was arranged by a top doctor at NIH, and cleared by the FDA. www.statnews.com/2026/06/23/e...

Eli Lilly gave extraordinary obesity drug access to a 79-year-old patient. Who was it?

Exclusive: STAT has learned that Eli Lilly and the FDA allowed a 79-year-old to gain extraordinary access to an experimental obesity drug through the agency’s “compassionate use” program.

statnews.com

“The whole point of AI tools is that I no longer need to retain information in my biological memory. My biological memory is for other things now. Important things. Like my Netflix password” 😂 inpreparation.substack.com/p/opinion-i-...

Opinion: I Was Not Allowed To Type Prompts Into ChatGPT During My Chalk Talk And This Is Discrimination

By Dr. Rachel Simmons, Postdoctoral Fellow, Stanford University

inpreparation.substack.com

this is honestly an excellent celebratory and motivational speech from Mamdani at the Knicks parade. i'm ready to run through a wall, and i'm not even a Knicks fan

A 20 year study on 2 NIH diversity programs in Science Advances shows they doubled undergrads' odds of getting a Ph.D. That is, before the funding for those programs and for the study itself was terminated last year: www.statnews.com/2026/06/17/n...

NIH diversity programs doubled undergraduates’ odds of getting a Ph.D., 20-year study finds

A new study found that two diversity-oriented programs supported by the NIH doubled the odds that an undergraduate would earn a Ph.D.

statnews.com

Now #1 on the Biochemistry “Most Read Articles” in the last 30 days list (in only 8 days!!) pubs.acs.org/action/showM...

Dr. Thomas Martínez@thomasmartinez.bsky.social · 2mo ago

Check out our new review article on intrinsically disordered #microproteins now out in @acs.org Biochemistry! pubs.acs.org/doi/10.1021/...

Now #1 on the Biochemistry “Most Read Articles” in the last 30 days list (in only 8 days!!) pubs.acs.org/action/showM...

Dr. Thomas Martínez@thomasmartinez.bsky.social · 2mo ago

Check out our new review article on intrinsically disordered #microproteins now out in @acs.org Biochemistry! pubs.acs.org/doi/10.1021/...

eating in mexico as a european has gotta be like hearing music for the first time

For context, this is one hundred ninety-two thousand, five-year biomedical research grants. More than five years of complete funding for the entirety of the NIH for cancer, heart disease, diabetes, Alzheimer’s, blindness, epilepsy, infectious diseases, etc… An entire generation of scientists.

Aaron Reichlin-Melnick@reichlinmelnick.bsky.social · 2mo ago

In the last 18 months, Congress has given DHS $240 billion — a quarter of a trillion.

The Trump Administration’s racist science policies have achieved some of their goals. The number of Black Principal Investigators has dropped by 10% between 2024 and 2025; while the number of Hispanic PIs has fallen by 7%. For research trainees, the numbers are far worse.

Trends in NIH Investigators by Sex, Race, Ethnicity, and Disability Status

This cross-sectional study assesses National Institutes of Health (NIH) data from fiscal years 2016-2025 comprising annual counts of principal investigators funded through research grants and fellowsh...

jamanetwork.com

Check out our new review article on intrinsically disordered #microproteins now out in @acs.org Biochemistry! pubs.acs.org/doi/10.1021/...

No Time to Fold: Intrinsically Disordered Microproteins in Action

Advances in genomics, proteomics, and bioinformatics have uncovered the existence of thousands of translated small open reading frames less than 100–150 codons in length that encode microproteins. In ...

pubs.acs.org

Yeah, there we go. I'm a little obsessed with tracking ignored warnings from scientists as they are vindicated.

"The document itself is an odd grab-bag of micromanaging grant processes, assertion of presidential power, and airing of cultural grievances... Its lack of coherence, however, will not prevent it from causing staggering damage to the US scientific system." 👇 arstechnica.com/science/2026...

Proposed new US funding rules: We can cancel any grant at any time

Peer review now optional, political staff would screen grants for forbidden topics.

arstechnica.com

Comments are now open. You can comment here: www.regulations.gov/search?filte... Note that even if the administration goes ahead with this abomination, the comments are essential to aid subsequent litigation! 2/2

Jordy's 'Just My Two Cents' on Breakfast TV

ALT: Jordy's 'Just My Two Cents' on Breakfast TV

static.klipy.com

Summary of Key Changes in OMB’s Proposed Federal Financial Assistance Rule. Russell Vought is going destroy American Science. elizabethginexi.substack.com/p/summary-of...

Summary of Key Changes in OMB’s Proposed Federal Financial Assistance Rule

Russell Vought is going destroy American Science

elizabethginexi.substack.com

The leadership and clarity of @MIT President Sally Kornbluth www.bostonglobe.com/2026/05/26/o...

America built the world’s greatest research engine. Now it’s shrinking. - The Boston Globe

At public and private universities across the country, high-impact science is being damaged and derailed.

bostonglobe.com

So... I got more information about this plan. The most important points follow on the next posts. 1/3

Jeremy Berg@jeremymberg.bsky.social · 2mo ago

I heard from several sources yesterday that NIH is planning to release a Request for Information (RFI) that apparently will include this: Scores and percentiles for NIH grant applications will not be shared with applicants although they will be provided to NIH program officers and staff. 1/3

MIT (endowment: $27B) shuttering three of its four main libraries is one of those news items that just knocks you off balance, auguring, as it does, profound and permanent changes to the entire institutional apparatus of higher education in this country.

eileen chengyin chow@chowleen.bsky.social · 2mo ago

“I write with dismay, grief and sorrow for the permanent closure of MIT Libraries Barker, Dewey and Rotch, and termination of library staff in those libraries. For MIT to be closing three of its four major libraries..." fnl.mit.edu/may-june-202...