Toshi Furukawa
@toshi-frkw.bsky.social
Psychiatrist, Cognitive-behavioural therapist, Clinical epidemiologist, who does systematic reviews, runs randomized clinical trials, performs meta-epidemiological studies and develops smartphone apps.
Isn't this amazing? More than 40 Palestinian and Israeli teenagers are getting ready to spend ten days together, most of whom come from bereaved families. mailchi.mp/315ac5fbda87...
Live Webinar from the PCFF Summer camp – The Summer of the Day After
mailchi.mp
But how could this SEM , with bidirectional arrows and without controlling for (time-dependent) confounders, show that anything is causing anything?
Celestial Mediation@celestialsem.bsky.social · 2mo agopsycnet.apa.org/doiLanding?d...
One-year follow-up of the RESiLIENT trial of smartphone CBT is out (n=3,280): CBT skills reduced major depression onset risk by 37–48%. But depression waxes and wanes. For the total burden of depression, behavioral activation + cognitive restructuring was the most effective. doi.org/10.1192/bjp....
📱 Could a smartphone app keep depression away — for nearly a year? A 3,280-person RCT says yes. CBT skills like behavioral activation & insomnia therapy cut the risk of major depression by up to 48% at 50 weeks. Prevention at scale is here. 🧵https://doi.org/10.1192/bjp.2026.10630
For primary prevention of stroke and heart attack people often expect more of statins than they get doi.org/10.1001/jama...
doi.org
💬 Editorial: Statin guidelines and patient preferences for #ASCVD prevention often misalign, supporting the need for clearer risk communication and shared decision-making in clinical practice. ja.ma/4eBIEX0
Thanks, Christian. Still get 403: Forbidden. Probably they do not allow access from outside the US.
Christian Webb, PhD@christianwebb.bsky.social · 3mo agoodd. the link works fine for me. Try the below link nsduhweb.rti.org/respweb/home... and then click Survey Data -> Latest Survey Results. Or if that doesn't work just try googling National Survey on Drug Use and Health
Some evidence of decreasing depression rates among adolescents from the latest National Survey on Drug Use and Health. 60% of teens with depression reported receiving mental health treatment (31% taking meds) www.samhsa.gov/data/sites/d...
It appears that regulatory agencies are pretty ignorant of predictive/diagnostic modeling. A very similar thing happened with the Japanese PMDA.
Eiko Fried@eikofried.bsky.social · 3mo agoFDA grants breakthrough device designation for schizophrenia/bipolar bloodtests, based on below paper with n=30 per disorder, "using 'leave-one-out' analyses, indicating that the models should be predictive when applied to independent data cohorts." Ouch. pmc.ncbi.nlm.nih.gov/articles/PMC...
But that is how education goes. We don’t have as many RCTs of educational methods, do we?
Darren Dahly@statsepi.bsky.social · 4mo agoUniversities: We teach critical thinking, and always ask for evidence, especially for extraordinary claims! 😤 Also universities 🫣:
After 40 years of working as psychiatrist and researcher, I cannot answer this question.
Joar Øveraas Halvorsen@joarhalvorsen.bsky.social · 4mo agoOncology has made impressive progress since the 1970’s. Et tu, clinical psychology?
Can I just propose a sensitivity analysis called ‘excluding studies where researchers did not due their due diligence in fabricating the data”? Obvious fakes excluded?
日本のBlueskyユーザーの皆さん、こんにちは！👋 英語以外の言語として初の、日本語公式アカウントを開設しました。 今後、 @bsky.app などの投稿の翻訳、日本向けの告知などを行っていく予定です。 ぜひこの投稿をリポストして、多くの方にこのアカウントを知っていただけるようご協力ください。
Parents Circle Nominated for the Nobel Peace Prize parentscirclefriends.org/parents-circ...
Parents Circle Nominated for the Nobel Peace Prize - American Friends of the Parents Circle
View press release We are honored to announce that the Parents Circle – Families Forum has been nominated for the 2026 Nobel Peace Prize. This recognition belongs, first and foremost, to our members: ...
parentscirclefriends.org
a webinar with bereaved Palestinian and Israeli peace builders -- parentscirclefriends.org/futureispeac...
[WEBINAR] The Future is Peace - American Friends of the Parents Circle
Join us on Monday, March 30, at 1pm ET / 10am PT for a special webinar with bereaved Palestinian and Israeli peace builders Aziz Abu Sarah and Maoz Inon, moderated by Todd Deatherage. On paper, Aziz a...
parentscirclefriends.org
This was a most illogical contrast one could ask. A clinician treats Mr A, and is interested in how they change over time. So a within-person change. But in deciding how to treat Mr A, the clinician must contrast Mr A receiving treatment X and not receiving it. Because we cannot do this (continue)
APA Journals@apajournals.bsky.social · 5mo agoClinical psychology depends on scientific evidence, but research from @chopwood.bsky.social et al. suggests that the kinds of data most commonly produced may not always align with what clinicians find most useful in practice. Read the article in American Psychologist: doi.org/10.1037/amp0...
It’s just another completely wrong use of the term statistical significant, don’t you think?
Martin Plöderl@ploederl.bsky.social · 5mo agoAgree. However, they found one significant interaction treatment x sex: a larger drug-placebo difference between men and women on day 2. HTE? Ore more likely a false positive finding, given there were 4 subscales of the MADRS and 6 time points and no adjustment of alpha pubpeer.com/publications...
I think they are even worse than that. They showed that sex is a prognostic factor. But they don't understand that prognostic factors essentially have no place in precision psychiatry. Precision psychiatry is about treatment*covariate interactions, i.e. about effect modifiers or HTE.
Martin Plöderl@ploederl.bsky.social · 5mo agoPrecision psychiatry? Study on gender-specific esketamine response. Some gender diffs but irrespective of group (esk/placebo). Only one significant gender x treatment interaction, on a specific day, with a specific outcome: p = 0.02. It did not occur to authors that this is likely a false positive
Most statin-eligible adults in the US and Japan desire greater absolute risk reduction than current statin efficacy provides before initiating therapy for #ASCVD prevention. ja.ma/4kDy02Y
💬 Editorial: Statin guidelines and patient preferences for #ASCVD prevention often misalign, supporting the need for clearer risk communication and shared decision-making in clinical practice. ja.ma/4rKRFAo
Today we published a survey of the SWD (smallest worthwhile difference) of statins, which found that the median SWDs exceeded its actual efficacy across all risk scenarios, suggesting that laypeople demand greater benefits than statins typically provide. jamanetwork.com/journals/jam...
Measuring Public Preferences for Statin Therapy Using the Smallest Worthwhile Difference
This survey study uses the smallest worthwhile difference to assess US and Japanese individuals’ willingness to take statins based on expected risk-reduction benefits and burden.
jamanetwork.com
In the shortest, use SMD, supplemented by CER/EER (control event rate & experimental event rate) for interpretability. mentalhealth.bmj.com/content/27/1...
Understanding effect size: an international online survey among psychiatrists, psychologists, physicians from other medical specialities, dentists and other health professionals
Background and objective Various ways exist to display the effectiveness of medical treatment options. This study examined various psychiatric, medical and allied professionals’ understanding and perc...
mentalhealth.bmj.com
Ioana A. Cristea@ioanaacristea.bsky.social · 6mo agoIn short, don’t dichotomize. It just gives the illusion of clarity, while losing information.
parentscirclefriends.org/petition/?mc...
Stand up for Peace Education - American Friends of the Parents Circle
The Dialogue Meeting in Israeli high schools has been one of the Parents Circle’s main programs for more than 20 years. The program allowed students to meet bereaved Palestinian and Israeli families w...
parentscirclefriends.org
Indeed, who with a sane/scientific mind can claim an effect size > 1.0? The readers, and the authors, should think twice.
Martin Plöderl@ploederl.bsky.social · 6mo agoSMD = −1.06 vs sham. I2 = 94% Not plausible. A look at the forestplots would be helpful (no access)
Perhaps an article of interest from our team: J Clin Epidemiol, 2022 vol. 150 pp. 90-97 Retracted randomized controlled trials were cited and not corrected in systematic reviews and clinical practice guidelines. www.ncbi.nlm.nih.gov/pubmed/35779...
Retracted randomized controlled trials were cited and not corrected in systematic reviews and clinical practice guidelines - PubMed
Many SRs and CPGs included already or later retracted RCTs without caution. Most of them were never corrected. The scientific community, including publishers and researchers, should make systematic and concerted efforts to remove the impact of retracted RCTs.
ncbi.nlm.nih.gov
Florian Naudet@floriannaudet.bsky.social · 6mo ago🎥 The NASEM panel “Systematic Reviews and Corrections and Retractions” is now featured on RestoRes website. With L Bero and J Wilkinson we discussed how corrections and retractions can impact the reliability of evidence syntheses. restores.univ-rennes.fr/highlights/n...
A Taylor & Francis journal has retracted a widely-read paper linking cardiac-related mortality to COVID-19 vaccines after an unsuccessful legal attempt by the lead author to block the withdrawal. That author says he is considering further legal action against the publisher.
Lawsuit fails to block retraction of paper claiming to link heart-related deaths to COVID-19 vaccines
Greg J. Marchand in a photo from his research institute’s website. A Taylor & Francis journal has retracted a widely-read paper linking cardiac-related mortality to COVID-19 vaccines afte…
retractionwatch.com
Relaxation was found, once again and again, to be harmful. www.sciencedirect.com/science/arti... as in acute treatment www.thelancet.com/journals/lan..., as in insomnia treatment jamanetwork.com/journals/jam..., as in panic disorder www.cambridge.org/core/journal..., and a few more coming.
Components of cognitive-behavioral interventions to prevent the onset of depression among the high-risk population: a systematic review and component network meta-analysis
Cognitive Behavioral Therapy (CBT) is a promising strategy for preventing onset of depression. This systematic review and component network meta-analy…
sciencedirect.com
