Tomas Machacek

@trichotom.bsky.social

Parasitic worms & immunity. 🪱🔬 Avian & human schistosomes. 🐭🦆 Swimmer's itch (www.cerkarie.cz), lungs & liver granulomas. 🏊🏻‍♂️🫁 Assistant professor at @sciencecharles.bsky.social.🎓 Secretary of @parazitologiecz.bsky.social. 🗒️

We found maternal helminth infection can promote antiviral immunity in offspring 🤱🪱 www.cell.com/cell-host-mi... Don’t worry, we are not suggesting we reinfect everyone with worms! Instead, we identified a microbiota-derived metabolite, Indole-3-propionic acid, that enhances antiviral immunity!

Maternal helminths rewire the microbiota to promote offspring antiviral immunity

Fernandes et al. show that maternal helminths, long-standing mammalian partners, confer antiviral immunity to offspring via the microbiota-derived metabolite indole-3-propionic acid (IPA). This work r...

cell.com

Where would the Arabs have reached if not for the plague that decimated the Byzantine Empire? And how did malaria influence the fight for American independence? 🤔 A light yet fascinating read about the germs that shaped our past — a perfect blend of infection and history. 📖🦠

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In schistosome 🪱-endemic areas, people are repeatedly reinfected — but we still don’t fully understand how T cell responses develop in these cycles. In my first ever last-author paper (😱) we investigate this, comparing endemic and repeat controlled human schistosome infection: rdcu.be/exH58

T cell responses in repeated controlled human schistosome infection compared to natural exposure

Nature Communications - In schistosomiasis-endemic regions, the cyclical nature of infection and treatment complicates understanding of host immune responses. Repeated controlled human Schistosoma...

rdcu.be

S nástupem letních teplot se nám začínají objevovat první případy cerkáriové dermatitidy (vyrážky z koupání). Víme už o dvou lokalitách ve Středních Čechách. ☀️🏊🏻‍♂️ Tak je možná fajn tu připomenout web pro veřejnost, který jsme k tématu připravili: www.cerkarie.cz 😉

Cerkárie.cz

Cerkáriová dermatitida Cerkáriová dermatitida (jinak také svědivá vyrážka z koupání nebo v angličtině „swimmer’s itch“) je alergická kožní reakce způsobená larvami (cerkáriemi) ptačích motolic, které ...

cerkarie.cz