Raquel Carreira Rodriguez did a brilliant job supervising local sixth form college students during work experience week at the Genome Damage and Stability Centre @gdsc-sussex.bsky.social @sussex.ac.uk. We are always impressed with their enthusiasm for STEM subjects! www.sussex.ac.uk/research/cen...

DNA replication and genome maintenance: from basic biology to human health www.embl.org/about/info/c...

DNA replication and genome maintenance: from basic biology to human health

embl.org

Why do gulls steal your chips — and how can you defend your dinner? 🍟 Professor Paul Graham joined BBC Radio 4’s Unexpected Elements to explain the science behind seaside snack theft. Listen here: https://ow.ly/UZkm50ZjgmT

Can you actually do a nine-to-five PhD? Nature readers weigh in www.nature.com/articles/d41...

Can you actually do a nine-to-five PhD? Nature readers weigh in

Nature readers share their PhD time-management woes.

nature.com

A new paper from Karim Labib's lab shows how TTF2 couples phosphorylated TRAIP to Pol ε, leading TRAIP to ubiquitylate the CMG helicase and triggering mitotic replisome disassembly at sites of incomplete DNA replication | Science www.science.org/doi/10.1126/...

A new paper from David Cortez's @dkcortez.bsky.social lab shows how FET protein assemblies modulate DNA replication fork reversal and replication stress responses! www.nature.com/articles/s41...

Not a bad analogy 🔬-⚽... The surprising career parallels between footballers and researchers www.nature.com/articles/d41...

The surprising career parallels between footballers and researchers

Sarah Blackford reflects on how early-career scientists and professional football players share similar motivations, pressures and challenges.

nature.com

Very proud of Jess Hudson representing the lab @gdsc-sussex.bsky.social at the 3rd Annual Symposium of the Sussex Cancer Research Centre @sussexcancer.org who promote bench-to-bedside research with stakeholders with lived experience of cancer. More on her work here: www.nature.com/articles/s41...

Congratulations John! @sussex.ac.uk Professor John Spencer wins Royal Society of Chemistry’s 2026 Bader Prize www.rsc.org/standards-an...

Sussex Professor wins Royal Society of Chemistry’s 2026 Bader Prize

The annual prize recognises individuals who have made outstanding contributions to organic chemistry

staff.sussex.ac.uk

A favorite day in the academic calendar @sussex.ac.uk is the Sussex Life Sciences PGR symposium: PhD students from all departments present their research, everything from evolutionary genetics to mechanisms of genome maintenance; keynotes by @aidaandres.bsky.social and Nitin Kapadia – what a treat!

Excited to finally share our preprint on mapping the genetic interaction network of the DNA damage response with combinatorial knockout screens led by Sam Hayward, Alina Vaitsiankova, and Tomas Lama-Diaz! www.biorxiv.org/cgi/content/...

Mapping the genetic landscape of the DNA damage response with Cas12a-based combinatorial knockout screens

The DNA damage response (DDR) is a complex network of cellular pathways that ensures the faithful maintenance of our genomes upon a wide array of genomic insults. To elucidate the functional architect...

biorxiv.org

Our work describing a phospho-activated DNA polymerase δ-RPA interaction and how RPA-ssDNA scaffolds break-induced replication is now available as published article! 📚 www.nature.com/articles/s41...

Break-induced replication is enhanced by a phospho-activated RPA-binding module in Pol32 - Nature Communications

Break-induced replication (BIR) is mediated by DNA polymerase d (Pol d). Here, the authors identify a phospho-activated RPA-binding module in Pol d which promotes BIR efficiency, providing a paradigm ...

nature.com

Pioneering palaeontologist Mary Anning was born #OnThisDay in 1799. Already ground-breaking by aged 12, she discovering the first correctly-identified ichthyosaur skeleton and helped revolutionise our understanding of the prehistoric Earth. She always worked with her dog, Tray. #WomenInSTEM

A pleasure to host Ilirjana Bajrami from @crick.ac.uk @westlabcrick.bsky.social at the Genome Centre in Sussex @gdsc-sussex.bsky.social today for a fantastic talk on the effects of PARPi at centromeric DNA.

Posted old school by the Skipper Shack Seaford beach 👍

Happy to share our new review in @annualreviews.bsky.social on abasic sites and their impact on DNA replication written by @angelotaglialatela.bsky.social. www.annualreviews.org/content/jour...

Endogenous Sources of Abasic Sites and Implications for DNA Replication: Mechanisms of Fork Stalling and Recovery

Apurinic/apyrimidinic (AP) sites, also known as abasic sites, are among the most frequent DNA lesions, arising spontaneously or as intermediates in base excision repair. Their structural impediment to...

annualreviews.org

Nature research paper: Evolutionary characterization of lung cancer metastasis go.nature.com/424XvC0

Evolutionary characterization of lung cancer metastasis - Nature

DNA-sequencing data from primary tumours and paired metastases from participants in the TRACERx lung study and PEACE autopsy programme are used to analyse the metastatic diversity of advanced non-small cell lung cancer and the seeding patterns that underpin it.

go.nature.com

‘In every drop of paint he slurped, you see the Holocaust’: the genius and torments of Georg Baselitz

‘In every drop of paint he slurped, you see the Holocaust’: the genius and torments of Georg Baselitz

The German artist lived through Nazism and communism – and his horrific, shaming works, including a masturbating Hitler, forced his country to face its past. Yet in later life, he beautifully captured human frailty, portraying himself and his wife nude

theguardian.com

Recognized failure as a necessary experience on the way to success in science. www.nature.com/articles/d41...

We need to talk about failure in science

Failure is part and parcel of research, but discussing it sometimes seems to be taboo in science. It doesn’t need to be.

nature.com

Geneticist J. Craig Venter, best known for his role in sequencing the human genome, has died aged 79. He spoke to Nature in 2023 about AI, sequencing the ocean – and why he had no plans to stop working. go.nature.com/4d4h1ns

Geneticist J. Craig Venter: ‘I consider retirement tantamount to death’

The human genome ‘maverick’ talks sequencing the ocean, setting up a health-screening company after checking his own genes — and why he has no plans to stop.

go.nature.com

Entries are now open for our 2026 #ScientistAtWork photo competition! 📸 Capture a moment in your working day for the chance to win £500 and see your winning image in print go.nature.com/4tEjtbc

#ScientistAtWork 2026: Nature seeks striking photographs that capture researchers at work

Competition winners receive a cash prize and will see their images featured in Nature.

go.nature.com

The @acmedsci.bsky.social Professorship Scheme hugely impacted my work, helping me @gdsc-sussex.bsky.social to do groundbreaking research: www.nature.com/articles/s41.... It offers up to £500k to researchers moving to the UK for a full Professorship. Now open for applications! bit.ly/4tTaN0u

Academy of Medical Sciences Professorship Scheme

bit.ly

Students taking the Biodiversity and Ecology module met some unique labmates this term - including spiders, scorpions, beetles and a praying mantis! Explore our #Ecology, #Conservation and #Environment courses: https://www.sussex.ac.uk/study/subjects/ecology-conservation-and-environment #EarthDay

Online Now: Deciphering the dual effects of transcription on DNA replication elongation by replication-associated Micro-C Online now:

Deciphering the dual effects of transcription on DNA replication elongation by replication-associated Micro-C

Integrating replication-associated Micro-C and the reinforcement-learning-based computational framework Fun2, Zhangding et al. profile DNA-replication elongation driven by coupled replication forks at nucleosome resolution in mammalian cells and reveal that transcription has dual effects on replication elongation. Co-directional transcription facilitates fork progression, whereas head-on transcription blocks coupled forks.

dlvr.it

New University of Sussex research finds pesticides in 100% of garden birds tested — including eggs & chicks. The source? Common pet flea & tick treatments. Researchers are calling for better regulation and more awareness to protect both pets & the environment. Read more: https://ow.ly/f8X550YOnOx

NEW! You can now also find us over on LinkedIn — www.linkedin.com/in/gdsc-sussex

Can neuroscience help us understand addiction as a “broken brain” condition? Should this affect how the legal system assigns blame? Join Prof Hans Crombag for a Sussex Universe public lecture on brain science, law, responsibility and addiction. 📅 Wed 22 April | 6pm 🎟️ https://ow.ly/2PTc50YJRTF

The MRC- @acmedsci.bsky.social policy internship scheme offers first-hand experience of the medical science policy and communications environment. If you're interested in how policy is made, don't miss out! ⏰ Apply by the 27 April: apply.workable.com/academy-of-m...

'Huge' congratulations to Dr Luke Yates, on being awarded a highly competitive Academy of Medical Sciences' Springboard programme — for research investigating how cells coordinate the process of DNA repair, using advanced molecular imaging and genetic tools @acmedsci.bsky.social

The latest from the Caldecott lab @gdsc-sussex.bsky.social @sussex.ac.uk. Great story, congrats Larissa!

Molecular Cell @cp-molcell.bsky.social · 4mo ago

BRCA2-dependent maturation of nascent strands during DNA replication