Honored to see our recent work featured by the Herbert Irving Comprehensive Cancer Center!@columbiauniversity.bsky.social Congratulations to all my co-authors and collaborators on this exciting milestone! @albertociccia.bsky.social 📄 Genes & Development: genesdev.cshlp.org/content/earl...

The Means to an End of Aggressive Tumors

A project led by Columbia University scientists has revealed a key weakness in some of the most aggressive and treatment-resistant cancers, including gliomas and pediatric sarcomas.

cancer.columbia.edu

Our manuscript on the dependency of ALT-positive tumors on the DNA translocase SMARCAL1 is finally out in @genesdev.bsky.social. Big thanks again to the Min, Lazzerini Denchi and @cejkalab.bsky.social labs! @angelotaglialatela.bsky.social genesdev.cshlp.org/content/earl...

Alberto Ciccia@albertociccia.bsky.social · 7mo ago

Happy to share our new pre-print on the dependency of ALT-positive tumors on the DNA translocase SMARCAL1. Outstanding work of @angelotaglialatela.bsky.social in collaboration with the Min, Lazzerini Denchi and @cejkalab.bsky.social laboratories! www.biorxiv.org/content/10.6...

Everyone in our field needs to stop what they are doing and read this magnificent work of ART & KNOWLEDGE that just dropped!

Alberto Ciccia@albertociccia.bsky.social · 3mo ago

Excited to finally share our preprint on mapping the genetic interaction network of the DNA damage response with combinatorial knockout screens led by Sam Hayward, Alina Vaitsiankova, and Tomas Lama-Diaz! www.biorxiv.org/cgi/content/...

This work wouldn't have been possible without @angelotaglialatela.bsky.social, Jen-Wei Huang, @giuseppeleuzzi.bsky.social, and members of the labs of @traver.bsky.social, Raphael Guerois, @labvincenzo.bsky.social, Raul Rabadan, @nussenza.bsky.social, @jenscs83.bsky.social, @heyzajr.bsky.social.

Are you ready for the Summer? Social DNAing is! Check out the 2026 Summer line-up! Please note one schedule change on June 4th, 2026. Please RT! Sign up at cancer.columbia.edu/research/pro...

Happy to share our new review in @annualreviews.bsky.social on abasic sites and their impact on DNA replication written by @angelotaglialatela.bsky.social. www.annualreviews.org/content/jour...

Endogenous Sources of Abasic Sites and Implications for DNA Replication: Mechanisms of Fork Stalling and Recovery

Apurinic/apyrimidinic (AP) sites, also known as abasic sites, are among the most frequent DNA lesions, arising spontaneously or as intermediates in base excision repair. Their structural impediment to...

annualreviews.org

Another classic from @albertociccia.bsky.social & @angelotaglialatela.bsky.social!

Alberto Ciccia@albertociccia.bsky.social · 5mo ago

Happy to share our new review in @annualreviews.bsky.social on abasic sites and their impact on DNA replication written by @angelotaglialatela.bsky.social. www.annualreviews.org/content/jour...

This week Dr. Doksani will join Social DNAing to discuss telomere biology! Please note the US is now in summer saving time. Check you local time! www.cancer.columbia.edu/research/pro...

Happy to share our new pre-print on the dependency of ALT-positive tumors on the DNA translocase SMARCAL1. Outstanding work of @angelotaglialatela.bsky.social in collaboration with the Min, Lazzerini Denchi and @cejkalab.bsky.social laboratories! www.biorxiv.org/content/10.6...

Are you ready for 2026? Social DNAing is! See who is coming. Sign up at www.cancer.columbia.edu/research/pro...