We are excited to share two preprints reporting a mosquito-specific receptor for chikungunya virus and other alphaviruses! 🤩 www.biorxiv.org/content/10.6... www.biorxiv.org/content/10.6... @harvardmicro.bsky.social @harvardvirology.bsky.social @hhmi-science.bsky.social

Great to see this finally published! We describe channels at the poxvirus core wall involved in nucleic acid release. www.nature.com/articles/s41...

In situ structure of the poxvirus portal complex - Nature

Cryo-electron tomography uncovers the structure of a conserved hexameric ‘portal complex’ that spans the core wall in vaccinia virus, and shows how it is associated with viral functions such as a...

nature.com

One month left to apply (deadline August 31st)! 👇 #Virology #AcademicJobs #FacultyJobs #FacultyPosition #TenureTrack #GroupLeader

Daniel Hurdiss@danielhurdiss.bsky.social · last mo.

We are looking for an Assistant or Associate Professor to join us at the @utrechtvirology.bsky.social. Interested in building an independent research programme in a collaborative #virology environment? Please take a look and share with anyone who might be a good fit! www.uu.nl/en/organisat...

Targeting Picornavirus Nonstructural 2C Protein: Structure, Function, and Antiviral Discovery pubs.acs.org/aidcbc/artic...

Targeting Picornavirus Nonstructural 2C Protein: Structure, Function, and Antiviral Discovery

Abstract. Picornaviruses cause substantial human and veterinary disease, yet direct-acting antivirals remain limited. The nonstructural protein 2C is among

pubs.acs.org

Direct lipid interactions control SARS-CoV-2 M protein conformational dynamics and virus assembly www.nature.com/articles/s41...

Really looking forward to visiting ISTA in just over two months for the 9th Austrian #CryoEM Symposium! Excited to give an EMBO YIP Lecture, hear from a great line-up of speakers, and catch up with the cryo-EM community. Hope to see you there! www.imp.ac.at/research/cry...

We are proud to announce Dr. Laura M. K. Dassama, Dr. Daniel L. Hurdiss, and Dr. Patrick T. Dolan as the winners of the 2026 ACS Infectious Diseases Early Career Award. Read their full interviews: buff.ly/m7n10sW

🔎 Assistant or Associate Professor in Virology 📍 @utrechtvirology.bsky.social, Netherlands 🔗 instruct-eric.org/jobs/assista... For these jobs and more, make sure to visit our website: instruct-eric.org/jobs If you have a job that you would like to advertise with us, please get in touch!

Assistant or Associate Professor in Virology - Instruct-ERIC

Instruct-ERIC is a pan-European research infrastructure in structural biology, making high-end technologies and methods available to all European researchers.

instruct-eric.org

Now online! A viral ORFeome library for systems-level genetic dissection of host-pathogen interactions

A viral ORFeome library for systems-level genetic dissection of host-pathogen interactions

A scalable library of ∼13,000 barcoded viral open reading frames from >500 viral species enables functional genomic screens across the virome. Applying this platform identified viral regulators of cellular proliferation, antigen presentation, and interferon signaling. This platform enables systematic exploration of viral protein function.

dlvr.it

We are looking for an Assistant or Associate Professor to join us at the @utrechtvirology.bsky.social. Interested in building an independent research programme in a collaborative #virology environment? Please take a look and share with anyone who might be a good fit! www.uu.nl/en/organisat...

Assistant or Associate Professor in Virology

uu.nl

📢 We're hiring! We are looking for an Assistant or Associate Professor to join our team at Utrecht University. If you're excited about leading an independent research programme in a collaborative #virology community, we'd love to hear from you. Please share! 👇🦠 #AcademicJobs #FacultyPosition

Just back from #NIDO2026 in Hong Kong! 🇭🇰 It was a pleasure to present our latest work, catch up with colleagues, and see three Utrecht Virology Lab PhD candidates present their work. Thanks to the organisers for a fantastic meeting and EMBO YIP for the financial support. See you in Banff in 2029!

We had an amazing time at #NIDO2026 in Hong Kong! 🇭🇰🦠 We contributed four talks and one poster, covering virus replication, entry, and vaccine/antiviral development. Thanks to the organisers for a fantastic meeting and to everyone for the stimulating discussions. See you in Banff in 2029!

Congratulation to @danielhurdiss.bsky.social on receiving the inaugural Sir Dave Stuart Early Career Researcher Award. Daniel's research uses #cryoEM to investigate how viruses infect cells and replicate. Proud that Thermo Fisher Scientific sponsors this award.

Honoured to receive the first Sir Dave Stuart Early Career Award today. Dave was my PhD external examiner, making this award, recognising his contributions to structural biology, especially meaningful to me. Thank you to Instruct-ERIC and Thermo Fisher Scientific for championing ECRs.

Congratulations to Daniel for winning the Inaugural Sir Dave Stuart ECR Award! You can read more about this on our website: instruct-eric.org/news/inaugur...

Claudia Alen Amaro@claudialen.bsky.social · 2mo ago

At the @instruct-eric.bsky.social Biennial Structural Biology Conference, we are inaugurating a new award, the Dave Stuart award recognising achievements of an Early Career Researcher. And the first recipient is Daniel Hurdiss. This award is supported by @thermofishersci.bsky.social #IBSBC2026

Excited to share our new preprint! Using deep mutational scanning and multivalent engineering, we developed our SARS-CoV-2 spike-targeting macrocyclic peptide into a potent inhibitor that blocks infection in HAE cultures and protects hamsters after intranasal dosing. chemrxiv.org/doi/full/10....

Super happy to see the final version of our paper out now 🎉🎉🎉 www.science.org/doi/10.1126/... Proud of PhD student Rupesh @rupeshjayachandran.bsky.social and postdoc Erwan for doing really nice work on this 😊

Open and closed forms of assembled henipavirus nucleoprotein suggest structural basis of genome access

Henipavirus nucleoprotein assemblies exist in different conformations, indicating temporary release of genome for RNA synthesis.

science.org

Max Renner@maxrenner.bsky.social · 9mo ago

Our new preprint is out 🥳🥳🥳 Henipaviruses, like Nipah and Hendra, package their genomes inside helical shells built by thousands of nucleoproteins. These nucleocapsids are essential to protect the viral RNA, but how do they ever let the polymerase in to read the sequence? 👇

Temperature-Dependent Replication and Sensitivity to Innate Immunity of Human Coronavirus HKU1 www.biorxiv.org/content/10.6...

France confines more than 1,700 people to cruise ship over suspected norovirus death

France confines more than 1,700 people to cruise ship over suspected norovirus death

One elderly passenger on vessel docked in Bordeaux has died and about 50 people have symptoms, say officials French authorities have confined more than 1,700 passengers and crew members on a cruise ship docked in Bordeaux after a passenger died from suspected norovirus, officials have said. The Ambassador Cruise Line vessel carrying 1,233 passengers, most of them British or Irish, arrived in Bordeaux on Tuesday. One 90-year-old passenger had died and about 50 people had shown symptoms of the virus, French health officials said. Continue reading...

theguardian.com

With Eugene Koonin, we wrote a rather comprehensive review on the origin, evolution and organization of the #virosphere. We describe all 10 viral realms and the logic behind them, and so much more. Check it out! comptes-rendus.academie-sciences.fr/biologies/ar...

The OG of outbreak viruses on cruise ships needed to remind everyone who is boss. 115 infected on the carribean princess cruise ship in an ongoing outbreak. Sounds like my idea of hell on earth. Trapped at sea on a ship full of people with vomiting and diarrhea. abcnews.com/Internationa...

115 people sickened in norovirus outbreak on cruise ship: CDC

The outbreak was reported to the CDC on Thursday, during the cruise ship's April 28 to May 11 voyage.

abcnews.com

Honoured to receive the 2026 ACS Infectious Diseases Early Career Award alongside Laura Dassama and Patrick Dolan! Grateful for this recognition, and especially grateful to my wonderful colleagues, collaborators, and lab members who made the work possible. axial.acs.org/biological-c...

Biological and Medicinal Chemistry 2026 Lectureship and Award Winners | ACS Publications Chemistry Blog

Learn about the 2026 winners of ACS Publications' Biological and Medicinal Chemistry lectureships and awards.

axial.acs.org

Do you have a passion for communications and engagement? Do you think viruses are cool? We are recruiting maternity cover for our Comms and Engagement Lead here @cvrinfo.bsky.social, the largest virus research centre in the UK. Hybrid working options, generous salary, great people. Please share!

Open #postdoc fellowship in my group. Virus replication and cryo-ET. Projects can be tailored to ambitious candidates with diverse backgrounds, so don't hold back from applying! DM for more info. Deadline 22May. Apply here: umustipendie.varbi.com/en/what:job/... #virus #virology #teamtomo #cryoEM

As foot-and-mouth disease explodes in South Africa, experts warn of threats in other countries www.science.org/content/arti...

As foot-and-mouth disease explodes in South Africa, experts warn of threats in other countries

A viral strain originating in wild buffalo in Kruger National Park is spreading rapidly in cattle

science.org

PKR condensation at viral replication complexes initiates its activation www.cell.com/cell-reports...

PKR condensation at viral replication complexes initiates its activation

Blomqvist et al. show that protein kinase R (PKR) condensation on dsRNA exposed at MERS-CoV or ZIKV viral replication complexes initiates its activation. The NS4a protein encoded by MERS-CoV inhibits ...

cell.com

How are host proteases promoting coronavirus entry into cells? Find out by reading our latest manuscript led by @mattmccallum.bsky.social Brett Case Jack Brown & @youngjunpark.bsky.social in collaboration with @msdiamondlab.bsky.social 1/19 www.nature.com/articles/s41...

TMPRSS2-mediated coronavirus spike activation and inhibition - Nature Structural & Molecular Biology

Here, the authors elucidate TMPRSS2 protease recognition of the SARS-CoV-2 spike S2′ cleavage site, revealing the molecular basis of activation of membrane fusion, and show that antibodies recognizing...

nature.com

Check out our new study published today showing that HA head-reactive B cells primed by H3N2 infections in the 1990s can be recalled by contemporary pH1N1 viruses. A huge Penn-CEIRR effort, led by Grace Li from my lab. Congrats to Grace and team! www.cell.com/cell-host-mi...

Childhood immunological imprinting of cross-subtype antibodies targeting the hemagglutinin head domain of influenza viruses

Li et al. isolated H1/H3 cross-reactive antibodies targeting a conserved epitope in the HA head. These antibodies were mostly found in people born in the 1990s and can be elicited in ferrets by sequen...

cell.com

A new family of rolling-circle replication endonucleases widespread in archaeal viruses and plasmids. This family is unrelated to the HUH superfamily Reps, but distantly related to the bacterial Rep_trans enzymes. @narjournal.bsky.social academic.oup.com/nar/article/...