Thrilled to announce the upcoming Center for Epigenetic Research Symposium @mskcancercenter.bsky.social on Nov 17! 🎉 A full day of cutting-edge science featuring stellar external speakers & our outstanding trainees. Registration is now open! Join us in NYC or virtually from anywhere! link⬇️

Thrilled to announce the upcoming Center for Epigenetic Research Symposium @mskcancercenter.bsky.social on Nov 17! 🎉 A full day of cutting-edge science featuring stellar external speakers & our outstanding trainees. Registration is now open! Join us in NYC or virtually from anywhere! link⬇️

Did not have time to post about this before vacation. Such a joy to have this chat with @davidlabmsk.bsky.social and Nobel Laureate Charles Rice on Yael's amazing work, capitalising on chromatin biology to understand hepatitis. www.nature.com/articles/s41...

Q&A with Yael David and Charles Rice on using chromatin biology to understand hepatitis - Nature Structural & Molecular Biology

Yael David leads her lab focused on studying the fundamental mechanisms of epigenetic regulation of transcription at Memorial Sloan Kettering Cancer Center, and Charles Rice is the Maurice R. and Cori...

nature.com

A new lab picture is an opportunity to welcome two new postdocs to my awesome group: Kevin Schiefelbein (from @ninahartrampf.bsky.social), who received @snsf.ch & Giuseppe Quarto (from @fukslab.bsky.social) who received @embo.org Fellow! So proud & excited to see the great science you do!

🚨 New meeting this fall in Brussels! 🚨 Cutting-edge science, amazing colleagues, & a RARE career development workshop for trainees-covering pharma, consulting, writing, start-ups & more 🤩 #epigenetics2025 Registration is open!! @epicypher.bsky.social xcellsconferences.com/epigenetics2025

🧬Thrilled to be sponsoring this meeting, which includes great opportunities for trainees to learn about different career paths. #epigenetics2025 check it out! 🔗 xcellsconferences.com/epigenetics2025

Yael David@yaeldavidmsk.bsky.social · last yr.

🚨 New meeting this fall in Brussels! 🚨 Cutting-edge science, amazing colleagues, & a RARE career development workshop for trainees-covering pharma, consulting, writing, start-ups & more 🤩 #epigenetics2025 Registration is open!! @epicypher.bsky.social xcellsconferences.com/epigenetics2025

🚨 New meeting this fall in Brussels! 🚨 Cutting-edge science, amazing colleagues, & a RARE career development workshop for trainees-covering pharma, consulting, writing, start-ups & more 🤩 #epigenetics2025 Registration is open!! @epicypher.bsky.social xcellsconferences.com/epigenetics2025

OMW back from the Gordon on Cancer Genetics & Epigenetics, reflecting on an incredible week of science, sunshine, & inspiring conversations. Grateful for the chance to connect w/ rising PIs & brilliant trainees-thank you @matlupien.bsky.social & @shenhui1986.bsky.social for a special meeting! 🤩

Packing my favorite histone marks and heading to @stanford.edu @stanfordimmunology.bsky.social ! Thanks to Priscilla Yang for the invite! Come for the science, stay for the chromatin drama 🤩

Excited for this summer’s NYC Chromatin Club! Grad students & postdocs: submit your abstracts for a chance to present a poster or talk. Come connect w/ fellow epigenetic New Yorkers! #NYCChromatinClub @dshechter.bsky.social @vivrisca.bsky.social @epicypher.bsky.social @kjarmache.bsky.social

Excited for this summer’s NYC Chromatin Club! Grad students & postdocs: submit your abstracts for a chance to present a poster or talk. Come connect w/ fellow epigenetic New Yorkers! #NYCChromatinClub @dshechter.bsky.social @vivrisca.bsky.social @epicypher.bsky.social @kjarmache.bsky.social

Awesome NYC chem bio meeting yesterday🤩 Keynote Tom Muir led to a mini-reunion together with @nshahlab.bsky.social!

Primary @natcomms.nature.com article: "The molecular basis of Human FN3K mediated phosphorylation of glycated substrates" from Leemore Joshua-Tor, Yael @davidlabmsk.bsky.social, and colleagues. www.nature.com/articles/s41...

The molecular basis of Human FN3K mediated phosphorylation of glycated substrates - Nature Communications

Garg et al. determined structures of human Fructosamine-3-kinase (FN3K) bound with different nucleotide analogues and a small molecule sugar mimic substrate. Accompanied by biochemical analysis, they ...

nature.com

Big thanks to Viraj for the lovely and thoughtful write-up on our collaboration with Leemor! And major shoutout to Yang from my lab for the gorgeous biochemistry—so proud! ✨👏🧪

Viraj Sanghvi@oncolab.bsky.social · last yr.

Check out our article in @cp-trendsbiochem.bsky.social highlighting the elegant work by Joshua-Tor lab, @davidlabmsk.bsky.social, and team .Their findings shed light on the structural basis of FN3K function and open doors for targeting glycation-related diseases. @sanniejculbertson.bsky.social

It’s going to be a blast!!! Couldn’t ask for a better partner 🤩 Come hang out with us if you are at the ASBMB next week!

George Burslem@gburslem.bsky.social · last yr.

Excited to be co-chairing the Chemical tools to reveal new biology theme with @davidlabmsk.bsky.social!

Sign up here if you want to receive an email about our next session (April 22nd in the Columbia med school) docs.google.com/forms/d/e/1F... @davidlabmsk.bsky.social @kelseymonson.bsky.social @stearnslab.bsky.social

Postdoc Night Science (NYC)

Sign up here for monthly meetings for postdoctoral fellows in the NYC area to practice the creative scientific process. For questions contact Itai Yanai (itai.yanai@nyulangone.org)

docs.google.com

Had an absolute blast at the @mskcancercenter.bsky.social PDA Night Science event w/ @itaiyanai.bsky.social —improv exercises, big ideas, & a glimpse into the brilliant future of science! A pleasure to be hosted for such an inspiring and fun evening. #NightScience #FutureOfScience

Itai Yanai@itaiyanai.bsky.social · last yr.

It's true! Yael agreed on the spot, no questions asked! #TrueScientist!

Anything involving @itaiyanai.bsky.social? Count me in—no questions asked here either!! #MaybeIShouldHaveReadTheFinePrint

Itai Yanai@itaiyanai.bsky.social · last yr.

Postdoc Night Science NYC! Next session is Friday 4-6pm at MSK, to learn and practice the creative scientific process! The topic this time is the import/export of ideas. Yael David join us too! @davidlabmsk.bsky.social Limited spots: docs.google.com/forms/d/12bB... @kelseymonson.bsky.social

TFW you watch the @academyawards.bsky.social awards and see you face in the @mskcancercenter.bsky.social ad 🤩 #Oscars  ispot.tv/ad/6wa1/memori…

Wow, this means a lot coming from the folks @epicypher.bsky.social !! So lucky to have you as collaborators and hope that the next big hit will come from our joint work!! 🙏🏻🤩

EpiCypher@epicypher.bsky.social · last yr.

🧬🧪SO excited to read this paper - new from @davidlabmsk.bsky.social highlighting the role of nucleosome occupancy in Hep B viral infection + discovering a new potential therapeutic strategy for Hep B. A great story of how basic research can lead to new treatment strategies🌟

Huge thank you, Darko, for the super kind words and for this shoutout 💪🏻🤩🙏🏻

Darko Barisic@darkobar.bsky.social · last yr.

Absolutely fantastic work from the magnificent @davidlabmsk.bsky.social lab! Incredible science and amazing out-of-the-box approach. Congrats to all the authors and highly recommend the read. 🙌

I am extremely proud to see our work about Hepatitis B now published in @cellpress.bsky.social From basic research to identifying the key step of infection & a potential first drug for curing this devastating disease. This has been an incredible journey.🧵 www.cell.com/cell/fulltex...

A nucleosome switch primes hepatitis B virus infection

A reconstituted cccDNA platform facilitated the discovery of an early chromatinization event that promotes transcription of the hepatitis B virus (HBV) regulatory X gene. The use of a small-molecule c...

cell.com

Congrats Leemor Joshua-Tor @cshlaboratory.bsky.social for this new paper characterizing human FN3K! Happy to play a role in the biochemical analysis, beautifully done by my TPCB rock star student Yang Xiao 💪🏻🤩 @mskcancercenter.bsky.social @weillcornell.bsky.social www.nature.com/articles/s41...

The molecular basis of Human FN3K mediated phosphorylation of glycated substrates - Nature Communications

Garg et al. determined structures of human Fructosamine-3-kinase (FN3K) bound with different nucleotide analogues and a small molecule sugar mimic substrate. Accompanied by biochemical analysis, they ...

urldefense.com

Just another magical day at the office in our enchanted forest… Happy holidays from the David lab!! 🎄🕎🥂

Almost 8 years since our first encounter, 2 years as a tech, & 5 years as a joint PhD student with Samuel Bakhoum, I am so proud to see Albert defend his thesis, & the amazing David lab cheering from the lines. Great science & friends, & one sword of course🤩🫶🏻

So excited to share our new paper working w/ David Lyden, Han Kim & Jackie Bromberg (WCM), led by the amazing Inbal Wortzel & Ifé Akano where we revealed a new & unexpected function for chromatin on the surface of exosomes in #cancer #metastasis @ Nature Cancer! www.nature.com/articles/s43...

Unique structural configuration of EV-DNA primes Kupffer cell-mediated antitumor immunity to prevent metastatic progression - Nature Cancer

Lyden and colleagues find that immune developmental genes, such as apoptotic peptidase activating factor 1 (APAF1), support DNA packaging on the surface of tumor-derived extracellular vesicles that ar...

nature.com

Loved the idea, so I asked ChatGPT the same question. Obviously I am not parrot material

Eugene Valkov@eugenevalkov.bsky.social · 2y ago

ChatGPT, based on what you know about me, draw me a picture of what you think my current life looks like. (Love the parrot and the dog.)

Post a photo of yourself from a different era (middle school me)

Oded Rechavi@odedrechavi.bsky.social · 2y ago

Post a photo of yourself from a different era (undergrad me)

Wrapping up a great meeting at the Sylvester Cancer Center at the University of Miami, really great science and mainly great catching up with an amazing group of friends that are also amazing scientists 🤩 @kjarmache.bsky.social @fukslab.bsky.social @mitchguttman.bsky.social

East coast chromatin mafia @kjarmache.bsky.social