Yiliang Ding
@yiliangding.bsky.social
Tenured Group Leader @JohnInnesCentre, Honorary Professor @uniofeastanglia, Honorary Group Leader @BabrahamInst. Working on RNA structure functionalities
Prof. @yiliangding.bsky.social - “Investigating how plants use RNA to cope with stress” biodtp.norwichresearchpark.ac.uk/projects/inv... 4/4
Investigating how plants use RNA to cope with stress (DING_J26DTP3) | Doctoral Training Partnership
DING_J26DTP3
biodtp.norwichresearchpark.ac.uk
Very successful #CEPAMS2026 annual symposium! @johninnescentre.bsky.social @thesainsburylab.bsky.social Next one will be in Beijing next year😀
Big congratulations to my postdoc @haopengyu.bsky.social who will start his own group @slcuplants.bsky.social ! AI for plant science! Super exciting!
CEPAMS 2026 Annual Meeting👍Welcome remarks by @cristobaluauy.bsky.social and Caroline Dean @johninnescentre.bsky.social @thesainsburylab.bsky.social
New AI for plant scientists: PlantScience.ai 🧬 Expert-level plant biology Q&A with real citations. No misread jargon. No outdated info. Just verifiable answers from the latest literature. Virtual collaborator for real discovery. #Plantscience @mplantpcom.bsky.social www.cell.com/molecular-pl...
PlantScience.ai: An LLM-powered virtual scientist for plant science
PlantScience.ai is a virtual plant scientist that combines a continuously expanding knowledge graph with large language models to provide citation-traceable, expert-level answers across plant biology....
cell.com
Plant Science Research Weekly -- Unveiling PlantScience.ai: A niche LLM to power your plant science research (Molecular Plant) @yiliangding.bsky.social @haopengyu.bsky.social (Summary by Shakunthala Natarajan @shakunthalan.bsky.social) buff.ly/Tlb0wmk #PlantaePSRW
Big congratulations to my postdoc Ran on receiving Marie Sklodowska-Curie Postdoctoral Fellowship! Well done 👍 @johninnescentre.bsky.social
Big congratulations! Very beautiful work👍👍👍
Kelly Nguyen@kellythd-nguyen.bsky.social · 4mo agoProud to share the yeast telomerase structure, led by the talented @hongmiaohu.bsky.social in collaboration with the Wellinger and Chartrand labs. Discovered 37 years ago and took us nearly 7 years but totally worth the wait 😍. www.science.org/doi/10.1126/... www.youtube.com/watch?v=gFE4...
Our paper is now live🎉! Huge thanks to all co-authors for your support @yiliangding.bsky.social @johninnescentre.bsky.social @thesainsburylab.bsky.social Our journey of AI in plant science starts here, built for plant scientists, aimed at accelerating discovery. www.cell.com/molecular-pl...
PlantScience.ai: An LLM-Powered Virtual Scientist for Plant Science
PlantScience.ai is a virtual plant scientist that combines a continuously expanding knowledge graph with large language models to provide citation-traceable, expert-level answers across plant biology....
cell.com
Ever heard of foundation models but not sure where to start? 🤔 We wrote a review for RNA biologists, no AI background required 😊 Everything explained through RNA biology examples you already know 🧬 @yiliangding.bsky.social www.tandfonline.com/doi/full/10....
AI foundation models for RNA biology
RNA biology is undergoing a transformative revolution driven by AI foundation models. These models learn the intricate relationships between RNA sequence, structure, and function by training on vas...
tandfonline.com
The review Martin Howard and I have written on "Graded versus ON/OFF control in quantitative gene expression and epigenetic memory" is now available in The EMBO Journal DOI 10.1038/s44318-026-00750-y
It was a wonderful experience to receive my Blavatnik Awards in the UK Finalist medal in the gorgeous Banqueting House this week! Then give a public lecture at the Royal Society of Medicine! A giant thank you to the Blavatnik Family Foundation and the The New York Academy of Sciences
VACANCY - We’re looking for a Laboratory Technician to join the @yiliangding.bsky.social group, investigating the role of #RNA structure in the post-transcriptional regulation of gene expression. www.jic.ac.uk/vacancies/la... Closing date - 17 March Contract - 36 months, Full-time
Laboratory Technician (Ding Group) | John Innes Centre
An exciting opportunity has arisen for a Laboratory Technician to join the Cell & Developmental Biology Department, to support the cutting-edge science of the John Innes Centre.
jic.ac.uk
@science.org Evolution of error correction through a need for speed | Science #evolution 🧬🔬 www.science.org/doi/10.1126/...
Evolution of error correction through a need for speed
Kinetic proofreading is a class of error-correcting mechanisms in biology that expend energy to avoid mistakes during replication, transcription, and translation. Proofreading is typically assumed to ...
science.org
🚨New preprint! We built a cell-free genomics platform (GATO-seq) to probe transcriptional regulation and discovered a “super pause” sequence that triggers a new Pol II active-site conformation. Huge shout-out to @robertovn.bsky.social for pulling off this monster of a project. tinyurl.com/superpause
Check out Arc’s related open roles: job-boards.greenhouse.io/arcinstitute... Go behind the paper with the authors in this blog post: arcinstitute.org/news/multi-e...
MULTI-evolve: Rapid Evolution of Complex Multi-mutant Proteins | Arc Institute
The search space for protein engineering grows exponentially with complexity. To address this problem, we developed MULTI-evolve, a framework for efficient protein evolution that applies machine learn...
arcinstitute.org
Finding one mutation that improves a protein is hard. Finding five that work together is exponentially harder. Today in @science.org, Hsu and Konermann labs present MULTI-evolve, a lab-in-the-loop framework that does it in just one machine learning-guided round.
Happy #ChineseNewYear! Sending warmest wishes to JIC's Chinese communities, friends, followers and partners as we welcome the Year of the Horse 🐴
Big congratulations @kellythd-nguyen.bsky.social🥳👍👍👍
MRC Laboratory of Molecular Biology@mrclmb.ac.uk · 6mo ago@kellythd-nguyen.bsky.social, Group Leader in the Structural Studies Division, has been announced as a Finalist in the 2026 Blavatnik Awards for her work on telomerase. Congratulations to Kelly and to all the other Finalists! Read more here: blavatnikawards.org/news/items/y... #LMBintheNews
Big congratulations 🎉 👍👍👍
Michael Booth@drmikebooth.bsky.social · 6mo agoExciting news: I've been selected as a Finalist for the Blavatnik Awards in the UK 🧬 🥳 This is an incredible honour and I'm thankful to all my past and present group members, whom I have had the privilege to work with, and my collaborators and mentors www.eurekalert.org/news-release...
New paper out! i-Motif, not G-quadruplex, stability regulates insulin expression - published in @narjournal.bsky.social Team effort driven by Dr Dilek Guneri supported by Dr Chris Morris, @timcraggs.bsky.social, @yiliangding.bsky.social and Prof Steve Smith academic.oup.com/nar/article/...
Validate User
academic.oup.com
🧬🔬@science.org A genetically encoded device for #transcriptome storage in mammalian cells | Science www.science.org/doi/10.1126/... @broadinstitute.org
A genetically encoded device for transcriptome storage in mammalian cells
Understanding how cells make decisions over time requires the ability to link past molecular states to future phenotypic outcomes. We present TimeVault, a genetically encoded system that records and s...
science.org
Loving this beautiful cover image in this week's @science.org illustrating the paper which came out online late last year www.science.org/doi/10.1126/... #Plantscience
Postdomestication selection of MKK3 shaped seed dormancy and end-use traits in barley
Anthropogenic selection of grain traits such as dormancy has shaped the developmental trajectories of crops. In cereals, shortening dormancy provides rapid and even postharvest germination, but increa...
science.org
Science Magazine@science.org · 7mo agoIn domesticated barley, grains with low levels of dormancy can sprout before harvest in the field after exposure to dew, mist, or rain. Preharvest sprouting in barley and other cereals reduces the quality of mature grain and jeopardizes its end-use value. Learn more: https://scim.ag/3KVkV86
Proximity labeling users: check out this study by @zhixingchen2.bsky.social and Peng Zou, which establishes how much contact-dependence vs. diffusion is responsible for biotinylation — tl;dr TurboID has a much smaller effective radius! www.nature.com/articles/s41... 1/2
Spatial barcoding reveals reaction radii and contact-dependent mechanism of proximity labeling - Nature Chemical Biology
A DNA nanoruler platform enables precise measurement of the labeling radii of TurboID and APEX2, uncovering their contact-dependent mechanisms. These findings redefine the enzymology of proximity labe...
nature.com
🧬 @science.org A SWI/SNF-specific Ig-like domain, SWIFT, is a transcription factor binding platform | Science www.science.org/doi/10.1126/... @ckadoch.bsky.social @danafarber.bsky.social @harvardmed.bsky.social @broadinstitute.org @hhmi-science.bsky.social 🔬 #chromatin #transcription #cancer 🧫
A SWI/SNF-specific Ig-like domain, SWIFT, is a transcription factor binding platform
Mammalian SWI/SNF chromatin remodeling complexes modulate DNA accessibility and gene expression; however, their genomic targeting mechanisms remain incompletely understood. Here, we identify SWIFT (SW...
science.org
The Ding lab wishes you a joyful Christmas and a New Year filled with happiness and discovery ❤️❤️❤️
The work, recently published in the journal @science.org, was led by @weibingyang.bsky.social, with key contributions on RNA structure and localisation from @yiliangding.bsky.social: www.cepams.org/cepams-resea...
CEPAMS Research Unravels Key Mechanism Governing Plant Stem Cell Activity - CEPAMS
Left: the shoot apex of an Arabidopsis thaliana plant.Right: the shoot apical meristem. Actively dividing stem cells are shown in green, and the cell walls are labelled in magenta.
cepams.org
@science.org Chromatin buffers torsional stress during transcription | Science www.science.org/doi/10.1126/...
Chromatin buffers torsional stress during transcription
During eukaryotic transcription, Pol II must overcome nucleosome obstacles and, because of DNA’s helical structure, must also rotate relative to DNA, generating torsional stress. However, there is lim...
science.org
Exciting project!Great opportunity!
Prof. Zoë Waller@drzoewaller.bsky.social · 8mo agoWe are recruiting! PDRA to work on a BBSRC funded position with Prof. Yiliang Ding and Dr. Tim Craggs. We are looking for someone with experience with cell culture and gene expression analysis - Please do share. Happy to answer any questions. Details below: www.ucl.ac.uk/work-at-ucl/...
