Jeremy Baskin
@jeremybaskin.bsky.social
Associate Professor at Cornell University: chemical biology, cell biology, #lipidtime and membrane biology
bioRxiv/medRxiv have been dealing with endless bot attacks recently (plus usual DDOS stuff, etc). Tricky to address without impacting genuine users - many of you affected. Apologies. We're working with our hosting service on solutions & think we're getting there [he shouts in his Red Queen costume].
Delighted to share that Cornell's Chemistry–Biology Interface NIGMS Training Program has been renewed for another 5 years, to support interdisciplinary Ph.D. training across chemistry, biology & engineering! Grateful to our trainees, faculty mentors, & staff. chemistry.cornell.edu/news/nih-ren...
NIH Renews Chemistry–Biology Interface Training Grant
The National Institute of General Medical Sciences, part of the NIH, has awarded Cornell University a $2.5 million, five-year renewal of its Chemistry–Biology Interface (CBI) Predoctoral Training Prog...
chemistry.cornell.edu
I've been waiting for this to come out - the best papers combine really simple ideas with excellent execution. And just like that there's a metabolic label for imaging one of the two most common phospholipid classes in mammalian cells. Congratulations!
Jeremy Baskin@jeremybaskin.bsky.social · last wk.Thrilled to share our new work, co-developed w/Adrian Salic's lab: bioorthogonal probes for labeling PE, a multifunctional membrane lipid and source of important protein modifications. Congrats to Yuan-Ting Cho, Brittany White-Mathieu, Jade Xia, & Cindy Jao! onlinelibrary.wiley.com/doi/10.1002/...
Thrilled to share our new work, co-developed w/Adrian Salic's lab: bioorthogonal probes for labeling PE, a multifunctional membrane lipid and source of important protein modifications. Congrats to Yuan-Ting Cho, Brittany White-Mathieu, Jade Xia, & Cindy Jao! onlinelibrary.wiley.com/doi/10.1002/...
Bioorthogonal Tools for Ethanolamine Lipids and Protein Conjugates
An alkyne-tagged ethanolamine analog (AlkEA) enables bioorthogonal, metabolic labeling of endogenous phosphatidylethanolamine (PE) and its protein modifications. AlkEA is incorporated into PE via the...
onlinelibrary.wiley.com
This one is really important. Great work! Some papers don't go on the reading list, you open them right away. 🤓 I can't help but wonder whether there's another level of regulation via acyl chain identity... the PS threshold should highly depend on saturation degree.
Abdou Rachid Thiam@abdourachidthiam.bsky.social · last wk.A long-standing mystery in cholesterol biology: why is ER cholesterol sensing so switch-like rather than gradual? Our answer: cholesteryl ester phase separation in the ER membrane, which converts small lipid changes into a cooperative transcriptional response. www.biorxiv.org/content/10.6...
A long-standing mystery in cholesterol biology: why is ER cholesterol sensing so switch-like rather than gradual? Our answer: cholesteryl ester phase separation in the ER membrane, which converts small lipid changes into a cooperative transcriptional response. www.biorxiv.org/content/10.6...
ER cholesteryl ester phase separation underlies switch-like cholesterol sensing
Cellular lipid homeostasis requires mechanisms that detect subtle changes in lipid abundance and trigger rapid, coordinated responses. The INSIG/SCAP/SREBP2 pathway provides a central feedback system ...
biorxiv.org
Congratulations to all the winners and particularly @wallaceucsf.bsky.social, @samlewis.bsky.social, @veronicasegarra.bsky.social, @mattwelchlab.bsky.social and @davidbreslowlab.bsky.social! 🥳🎉🎊
American Society for Cell Biology@ascbiology.bsky.social · 2w agoCongratulations to the 2026 ASCB Honorific Award Winners! ASCB is proud to recognize scientists whose research, mentorship, education & leadership are helping shape the future of cell biology. See all the awardees: https://www.ascb.org/society-news/ascb-announces-2026-honorific-award-winners/
Chemistry World@chemistryworld.com · 2w agoA facility housing large tanks of methyl methacrylate, the monomer form of polymethyl methacrylate was overheating this May. @chemjobber.bsky.social explores the lessons learned & how risky runaway polymerisation can be prevented in the future: www.chemistryworld.com/opinion/earl...
Check out this comprehensive proteomics study led by @cookkate.bsky.social, @nadlerlab.bsky.social and colleagues using panels of bifunctional lipids to map differential lipid-protein interactome networks! #lipidtime
André Nadler@nadlerlab.bsky.social · 2w agoLipids build the membranes of all cells, but identifying their precise functions is extremely challenging. Here’s our attempt to change that: How to find and understand lipid-protein interactions, by Katelyn Cook & company. www.biorxiv.org/content/10.6...
Lipids build the membranes of all cells, but identifying their precise functions is extremely challenging. Here’s our attempt to change that: How to find and understand lipid-protein interactions, by Katelyn Cook & company. www.biorxiv.org/content/10.6...
Cool method for nano pore based peptide sequencing, nice use of copper-free click chemistry as well! www.nature.com/articles/s41...
Sequential reading of a stepwise-shortened peptide immobilized on nanopore - Nature
A nanopore-based ‘chop and measure’ method sequences peptides at single-amino-acid resolution by using enzymatic digestion to progressively shorten the N terminus one residue at a time,...
nature.com
The 2027 Chemistry Faculty Jobs List has 23 tenure-track positions and 1 teaching-only position: docs.google.com/spreadsheets... #facultychemjobs #chemsky #chemchat ⚗️🧪
The 2027 Chemistry Faculty Jobs List
docs.google.com
Phosphatidylserine and RhoB connect PI4P and PA #metabolism to maintain plasma #membrane identity. New study from Shiying Huang, Tamas Balla, Jeremy M. Baskin @jeremybaskin.bsky.social, @weillinstitute.bsky.social and colleagues: rupress.org/jcb/article/... #lipid
The last leg of my trip to Japan was at the 55th Naito Conference on Chemical Biology: inspiring science in beautiful Hokkaido at the incomparable Chateraisé Gateaux Kingdom — a 3-in-1 hotel, spa, and sweets factory. I’ve been surrounded by so many delicious lipids all week! 🤤
Excited and grateful to have been promoted to Professor. Many thanks to the outstanding students and postdocs in my lab and to my colleagues at Cornell and across the #chembio and #lipidtime communities for your continued support!
Fantastic #lipidtime conversations yesterday at UTokyo — thank you to Noboru Mizushima for hosting my visit!
Thrilled to share this #lipidtime mechanism story in @jcb.org where, led by Shiying Huang and in collaboration with Tamas Balla’s lab, we uncover plasticity in phospholipid metabolism to preserve plasma membrane identity and integrity in the face of disease-relevant perturbations!
Journal of Cell Biology@jcb.org · 2mo agoHow does the plasma #membrane preserve its #lipid identity under stress? The Baskin and Balla labs report a homeostatic circuit linking PI4P, phosphatidylserine, RhoB, and phospholipase D-driven phosphatidic acid. rupress.org/jcb/article/... @jeremybaskin.bsky.social
How does the plasma #membrane preserve its #lipid identity under stress? In @jcb.org, the Baskin and Balla labs report a homeostatic circuit linking PI4P, phosphatidylserine, RhoB, and phospholipase D-driven phosphatidic acid. rupress.org/jcb/article/... @jeremybaskin.bsky.social
Jeremy Baskin @cornellupress.bsky.social sharing exciting new #lipidtime discoveries @onoinitiative.bsky.social chem bio symposium @stanford-chemh.bsky.social
Hello, Stanford — excited to be in town for the @onoinitiative.bsky.social symposium today! @stanford-chemh.bsky.social
New online: A single-vesicle fluorescence microscopy platform to quantify phospholipid scrambling
A single-vesicle fluorescence microscopy platform to quantify phospholipid scrambling
Nature Structural & Molecular Biology, Published online: 15 June 2026; doi:10.1038/s41594-026-01821-8Veit et al. present a fluorescence microscopy platform to measure protein scramblase-mediated lipid flipflop across membranes by imaging single vesicles containing fluorescent lipid probes to quantify precise transport rates.
dlvr.it
Just want to point out the GM of the Stanley Cup winning team is a chemist who was in Jeff Long’s first class of graduate students. (I was an undergrad in the group at the same time and know him!) en.wikipedia.org/wiki/Eric_Tu...
Eric Tulsky - Wikipedia
en.wikipedia.org
My primary academic conference is in a few weeks. I have given a good number of conference presentations over the years, and possibly moderated even more often than I've presented. Advice for anyone who wants it, in a thread:
So excited to share our new paper out today in @nature.com - 'LASER couples damage sensing to ESCRT assembly for lysosome repair'. This was an amazing collaborative effort with Claire Goul during our time in @robzonculab.bsky.social : www.nature.com/articles/s41...
LASER couples damage sensing to ESCRT assembly for lysosome repair - Nature
ATG8 conjugation on damaged lysosomes triggers rapid assembly of a protein complex containing TFG, which directs lysosomal membrane repair by recruiting ESCRT proteins to sites of damage.
nature.com
The ZMBH welcomes Dr. James Sáenz @jamessaenz.bsky.social as new Professor in Molecular Biology. James previously led a research group at B CUBE - Center for Molecular Bioengineering of Dresden University of Technology.
💡Join us for the SMART Symposium on Decoding the Glycome: Illuminating Biology's Last Uncharted Frontier 📆11–14 Nov 2026 | Shenzhen 🌏From glycan mapping to glyco‑engineered therapies 🔗Register: symposia.smart.org.cn #SMARTSymposia #SMARTshenzhen #Glycome #Glycobiology
Hallo, Dresden, you hotbed of #lipidtime research! Thanks to @nadlerlab.bsky.social for hosting me at @mpi-cbg.de yesterday — and looking forward to giving the plenary talk at the European Symposia of Bioorganic Chemistry meeting later today!
