Argyris Zardilis

@zardilis.bsky.social

Scientist @slcuplants.bsky.social I like to wonder (το θαυμάζειν) about the world https://www.slcu.cam.ac.uk/people/argyris-zardilis

In a collaboration between the Crick and @embl.org, researchers used a mix of experimental work in zebrafish and theoretical modelling to discover a feedback loop between an embryo’s changing material properties, such as its rigidity, and the signalling molecules that guide patterning.

The physical properties behind an embryo’s body plan

How rigid a tissue is coordinates a crucial period of cell patterning, ensuring that embryos develop the right shape and organise their cell layers correctly at the same time.

crick.ac.uk

How can we learn tissue mechanics directly from cell patterns and images? In our new preprint, we introduce VertAX, a differentiable vertex-model framework in JAX for simulating epithelia, inferring parameters, and designing target tissue behaviors. shorturl.at/PUzT0 1/5

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New Perspective form Rory Maizels & me: "Gene regulatory networks: from correlative models to causal explanations" Gene regulatory networks are supposed to give us mechanistic explanations of development, so why are we drowning in 'hairballs' of statistical correlations? rdcu.be/e7zx7

Gene regulatory networks: from correlative models to causal explanations

Nature Reviews Genetics - In this Perspective, Maizels and Briscoe discuss the limitations of current models of gene regulatory networks and outline solutions to harness data abundance without...

rdcu.be

The new ShapeEmbed deep learning method helps quantify shapes in bioimages 🔬 It learns to encode 2D object outlines into descriptors that are invariant to several geometric transformations. Great for robust cell shape analysis, classification & exploring phenotypes. neurips.cc/virtual/2025...

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Interested in doing an interdisciplinary PhD to elucidate signalling centres that orchestrates limb regeneration? Come to work with the amazing @canaztekin.bsky.social and myself!!

@canaztekin.bsky.social · 8mo ago

🚨We are recruiting two PhD students 🚨 1) Quantitative & dynamic analysis of limb-regenerative signaling centers w/ @osvaldo-chara.bsky.social 📶🧮💻 🔗https://www.phd.tuebingen.mpg.de/80704/Quantitative-and-dynamic-analysis-of-limb-regenerative-signaling-center-interactions

Congratulations Elise Laruelle & @robinsonsci.bsky.social on your @acceleratescience.bsky.social - @c2d3.cam.ac.uk funded project "Plant automatic cell lineage reconstruction" More info www.slcu.cam.ac.uk/news/plant-a... Illustration by Elise Laruelle & leaf images by @sainikumud.bsky.social

Graphic depicting the Plant Automatic Cell Lineage Reconstruction project which aims to train a neural network to recognise “sister cells” in mature plant leaves and reconstruct their complete cell division history from a single image.. Illustration by Elise Laruelle and leaf images by Kumud Saini.
Accelerate Programme for Scientific Discovery@acceleratescience.bsky.social · 8mo ago

We are delighted to announce the 2025 Accelerate – @c2d3.cam.ac.uk funded projects! 🎉 Projects will catalyse discoveries to accelerate scientific progress & create AI tools capable of delivering benefits for science & society. Find out more: bit.ly/4rpvSiy

Photo of a whale, brain scans, a city and a leaf to represent awarded Accelerate-C2D3 funded projects

The BM^2 Lab is hiring a Ph.D. student to work on a variety of problems connected to modeling of morphogenesis in plants (i.e. ovule curvature formation, fixed handedness establishment in certain plant organs and its link to cell wall mechanics). Please share!

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Very happy to share MODIS - a new Multi-Omics Data Integration method for Small and unpaired datasets! We solve a long-standing problem in the field: how to perform data integration for small unpaired datasets Our solution: learning with class imbalance on both reference and target datasets!

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