Most of us develop gene mutations linked to blood cancer as we age, but only a small proportion go on to develop the disease. New research from @benjaminwerner.bsky.social and team at BCI explores why, showing how mutated cells compete and evolve over time. 🧪 #medsky #oncosky @qmul.bsky.social

Study offers clues to blood cancer risk, revealing how gene mutations compete over time

Researchers have developed a new way to understand how genetic changes linked to blood cancer evolve in our cells, offering new insight into predicting blood cancer risk.

bci.qmul.ac.uk

Summer conference plans: (1) Cancer Population Genetics Meeting, London, UK (2) Pezcoller Symposium, Trento, Italy (3) ECMTB/SMB, Graz, Austria Always happy to chat science or having lunch/drinks together with known and new faces 😊

King's College London are seeking a Lecturer in Applied Mathematics (Quantitative Modelling) to "develop an independent research programme in applied mathematics, mathematical modelling, or a closely related area" www.jobs.ac.uk/job/DRG116/l...

Lecturer in Applied Mathematics (Quantitative Modelling) at King's College London

Recruiting now: Lecturer in Applied Mathematics (Quantitative Modelling) on jobs.ac.uk. Click for details and explore more academic job opportunities on the top job board

jobs.ac.uk

If you work on quantitative cancer genomics, please consider submitting an abstract for our next "Cancer Population Genetics Club" #CANPOP meeting hosted @icr.ac.uk on 15 June 2026. CANPOP is free to attend. Registration & abstract submission here: docs.google.com/forms/d/e/1F...

Behind the paper: Mathematical modelling predicts selective sweeps are restricted to early stages of tumour growth mathematical-oncology.org/blog/selecti... by @alexsteinresearch.bsky.social #cancer #evolution #mathonco

Mathematical modelling predicts selective sweeps are restricted to early stages of tumour growth

mathematical-oncology.org

mathematical-oncology.org

Our paper "Selective sweep probabilities in spatially expanding populations" is out in Nature Communications! Our work extends the theory of population genetics and contributes to our understanding of cancer evolution. doi.org/10.1038/s414...

Selective sweep probabilities in spatially expanding populations - Nature Communications

In this study, the authors use mathematical modelling and analysis to understand how mutations spread through populations that are expanding in space. The results shed light on the evolution of biolog...

doi.org

Academics often lament that hardly any master’s projects get published. The student moves on. Other research takes priority. No one has time to do the final analyses. Here I tell how one master’s project was, through persistent teamwork, finally carried over the finish line: go.nature.com/4aKs7N3

On the expansion and evolution of a master’s project

Academics often lament that hardly any master’s projects – even the best ones – get published. The student moves on. Other research takes priority. No one has time to do the final analyses. Here I tel...

go.nature.com

An incredible opportunity for early career researchers - Imperial's Faculty of Medicine is hiring 20 Assistant Professors!

Department of Immunology and Inflammation@imperialimmuno.bsky.social · 6mo ago

We're #hiring for new non‑clinical Assistant Professors! Keen to join us at the Department of Immunology and Inflammation? Make sure to select ‘Immunology and Inflammation’ as your first preference when applying. ✍️Apply by 11 March 2026. 👉 www.imperial.ac.uk/jobs/search-...

If you’re interested in machine learning and mathematical modelling, we’re recruiting a PhD student to develop new methods for studying cancer evolution at @imperialimmuno.bsky.social www.findaphd.com/phds/project...

Developing machine learning methods to infer the evolution of haematological cancers at Imperial College London on FindAPhD.com

PhD Project - Developing machine learning methods to infer the evolution of haematological cancers at Imperial College London, listed on FindAPhD.com

findaphd.com

Job offer: PhD-level biostatistician with ML&omics experience to work on prediction models for CAR T cell therapy, in an exciting clinical trial - spatial omics - data science consortium (LOOP/INTeRCePT3.0 centered in Zurich; this position in Heidelberg) embl.wd103.myworkdayjobs.com/en-GB/EMBL/j...

🧬 We're hiring a postdoc! Come chart somatic evolution with us using cutting-edge long-read & single-cell tech 🔬 Computational bio background + love for complex cancer genomics = perfect fit 📍 Leuven, Belgium 📧 jobs.vib.be/j/129915/ #postdoc #genomics #hiring

Postdoctoral Researcher in Cancer Genomics - VIB

Chart tumour evolution using cutting-edge long-read and single-cell multiomics Who we are The Integrative Cancer Genomics lab (Jonas Demeulemeester) is embedded within the VIB – KU Leuven Center for ...

jobs.vib.be

We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT

Open postdoc position in our lab @icr.ac.uk to develop a cfDNA test for #early detection of colorectal #cancer in inflammatory bowel disease #IBD: jobs.icr.ac.uk/vacancies/14... It's bench-to-bedside research, translating biology of pre-cancer evolution. Funded by @bowelcanceruk.bsky.social

Postdoctoral Training Fellow - Genomics and Evolutionary Dynimcs in Sutton | The Institute of Cancer Research

View details and apply for this Postdoctoral Training Fellow - Genomics and Evolutionary Dynimcs vacancy in Sutton. Salary: Dependent on relevant Postdoctoral experience. Durati...

jobs.icr.ac.uk

My supervisor, Jonas Demeulemeester (@jdemeul.bsky.social), is hiring a Postdoc to study Cancer Genomics at the VIB-KU Leuven Center for Cancer Biology: jobso.id/pbgr Cool projects, great team, and super working environment in general! Check it out!

Postdoctoral Researcher in Cancer Genomics - VIB

Chart tumour evolution using cutting-edge long-read and single-cell multiomics Who we are The Integrative Cancer Genomics lab (Jonas Demeulemeester) is embedded within the VIB – KU Leuven Center for ...

jobso.id

Do you like theoretical biology, mathematical&conceptual modelling and want to apply yourself to cutting-edge research at all levels of biology, from molecules to ecosystems? Come to EMBL! Scope includes physics-based models, emergence, statistics, ML/AI embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Excited to announce that registration for the 13th @mathonco.bsky.social workshop on Treatment Revolution is now open. Held onsite @moffittnews.bsky.social Nov 2-Nov 7 #MoffittIMO more details: imo13.eventbrite.com. Deluxe travel awards are available on a competitive basis, apply by 10/03!

Studying cancer evolution needs multi-region or single cell seq for phylogenetics, right? Amazingly (I think!) we found single-sample bulk methylation suffices, via analysis of "fluctuating methylation". In @nature.com today led by brilliant @calumgabbutt.bsky.social www.nature.com/articles/s41...

Fluctuating DNA methylation tracks cancer evolution at clinical scale - Nature

Cancer evolutionary dynamics are quantitatively inferred using a method, EVOFLUx, applied to fluctuating DNA methylation.

nature.com

Long-read single-cell genome, transcriptome and open chromatin profiling links genotype to phenotypes. https://www.biorxiv.org/content/10.1101/2025.09.08.674950v1

New preprint! Let me tell you a story about trees, caterpillars, brooms, entropy, and getting scooped by 50 years. Rooted trees of all shapes and sizes crop up all over biology, computing and elsewhere. How can we best compare the shapes of these myriad trees? 1/14 arxiv.org/abs/2507.08615

In #GENETICS, @alexsteinresearch.bsky.social‬ and @benjaminwerner.bsky.social‬ present a new study about the population genetics of cancer. Learn about their theoretical assessment of the genetic makeup of cancers before and after treatment: buff.ly/AE4sLUH

Interested in population genetics of cancer? If so, have a look at our manuscript accepted by @genetics-gsa.bsky.social, in which we provide a theoretical assessment of the genetic makeup of cancers before and after treatment!

Benjamin Werner@benjaminwerner.bsky.social · last yr.

Very happy that @alexsteinresearch.bsky.social manuscript on the patterns of genetic heterogeneity before and after treatment is out now: academic.oup.com/genetics/adv... We build on and expand the population genetics theory of gITH. Very worth a read if you are interested in somatic evolution.

My department is hiring! Permanent faculty job (research + teaching) in applied maths. Mathematical biology would be highly appropriate. We're a friendly department in a large university in central London, recently merged with a big medical school. Apply by 1st June. www.jobs.ac.uk/job/DMY889/l...

Lecturer in Applied Mathematics at City St George’s, University of London

Apply for the Lecturer in Applied Mathematics role on jobs.ac.uk, the top job board for academic positions in higher education. View details and apply now.

jobs.ac.uk

Thank you David @cancerevo.org and Simone @zaccasimo.bsky.social for building my PhD viva panel! I enjoyed the discussions and appreciate your time and effort to assess my PhD. And heartfelt thank you Ben @benjaminwerner.bsky.social and Katerina for guiding me through this PhD journey!

David Basanta@cancerevo.org · last yr.

Congrats Dr. @alexsteinresearch.bsky.social and also Alex's PhD supervisor @benjaminwerner.bsky.social for an excellent body of doctoral work pushing the frontiers of #mathonco and #cancerevo

Congratulations to a successful viva Dr. @alexsteinresearch.bsky.social Many thanks to @cancerevo.org and @zaccasimo.bsky.social to be examiners!

The University of Bern is looking for a Tenure Track Assistant Professor in Mathematical or Computational Biology: www.nature.com/naturecareer...

Tenure-Track Assistant Professor for Mathematical or Computational Ecology (80-100%) - Bern, Canton of Bern (CH) job with Institut für Ökologie und Evolution | 12834542

The Department of Biology at the University of Bern announces a vacancy for a Tenure-Track Assistant Professor to lead a new Division of Mathematic...

nature.com

We have an open #PhD #studentship as part of our "Black Leaders in Cancer" programme at @crukconvergence.bsky.social & @icrlondon.bsky.social. About computational modelling of T-cell evolution in cancer. www.findaphd.com/phds/project... I'm looking forward to meeting prospective students #CRUKfunded

📝New Author's summary about "Complexity-stability relationships in competitive disordered dynamical system" O Mazzarisi, M Smerlak and "Diversity begets stability: Sublinear growth and competitive coexistence across ecosystems" I Hatton, O Mazzarisi, A Altieri, M Smerlak

Resharing here a recent X post. In this preprint, we introduce an improved version of NanoSeq, a duplex sequencing protocol with <5 errors per billion bp in single DNA molecules, and use it to study the somatic mutation landscape of oral epithelium in >1000 people. 1/ www.medrxiv.org/content/10.1...

Somatic mutation and selection at epidemiological scale

As we age, many tissues become colonised by microscopic clones carrying somatic driver mutations ([1][1]–[10][2]. Some of these clones represent a first step towards cancer whereas others may contribu...

medrxiv.org

Alex just dropped his magnus opus on BioRxiv scholar.google.com/citations?vi...