Just out! 👀 for TFs that regulate TEs.Clara's work with @tamas-schauer.bsky.social @marliesoomen.bsky.social @palmrinmoy.bsky.social and bluesky-less lab members 🌎 identifies TBP as a regulator of specific ERVL class: MaLRs in 🐭embryos -as always -feedback welcome👍 link.springer.com/article/10.1...

We go live!!! Join us Munich July5-7th to hear exciting research on #Replication by leaders in the field AND !! registration is FREE 🥳 (but mandatory) - we hope to see many in Munich 🍺 @helmholtzmunich.bsky.social @replifate.bsky.social @epicrossborders.bsky.social replifate.eu/event/meetin...

Events for February 2026

06-07 July 2026 | Munich, GermanyDNA Replication and Its Impact on Genome and Chromatin MaintenanceWe are RepliFate, a European Training Doctoral Network dedicated to understanding how DNA replication...

replifate.eu

Today i learned about Caroline Herschel! the first woman to receive a salary as a scientist! en.wikipedia.org/wiki/Carolin...

"It is crucial for us, young scientists, to come together from different countries and build a network," says Marlies Oomen, EMBO Postdoctoral Fellow at Helmholtz Munich. 🧪 https://www.embo.org/people/global-mobility-sparks-scientific-creativity/ #networking #LifeSciences #research #funding

Our new preprint is out: www.biorxiv.org/content/10.6... We show that GRN benchmarks commonly used can overestimate performance due to negative-sampling choices, sometimes allowing simple degree-based baselines to rival more complex GNNs. A reminder of why bias-aware evaluation matters!

Hidden sampling biases inflate performance in gene regulatory network inference

Accurate reconstruction of gene regulatory networks (GRNs) from single-cell transcriptomic data remains a major methodological challenge. Recent machine learning approaches, particularly graph neural ...

biorxiv.org

It’s a story of marks written early, carried through a long silence, and then suddenly speaking again. A bit like memory itself.

After a long journey, I'm happy to share that my PhD work is finally published in Nature Communications. Grateful to all my co-authors!

Eva Hörmanseder@evahoermanseder.bsky.social · 8mo ago

We probably shouldn’t have favourites amongst projects in the lab, but this one was mine. I’m so pleased we can finally share it: Our work is now out in Nature Communications: 🔗 nature.com/articles/s41467-025-67692-7

Congrats on this exciting story @sandrani.bsky.social and team!!

Rob Schneider@robertife.bsky.social · 8mo ago

Excited to share new manuscript on histone acylations, exploring how H4K16 acylations regulate inter and intranucleosomal interactions and how they confer resilience to metabolic challenges in vivo. Thanks to all authors +1 author @sandrani.bsky.social Enjoy 👇👇 www.sciencedirect.com/science/arti...

absolutely losing it at my 14yo's biology homework

Excited to announce that our peer-reviewed manuscript is online in the Development journal @dev-journal.bsky.social. The manuscript was much improved through the peer-review process, and I am grateful to the reviewers for their valuable feedback. journals.biologists.com/dev/article/...

Feed-forward loops by NR5A2 ensure robust gene activation during pre-implantation development

Pioneer transcription factors are crucial for regulating zygotic genome activation and cell differentiation during mouse pre-implantation development. However, how pioneer factors function collectivel...

journals.biologists.com

We have just published a tribute to John Gurdon, reflecting on his scientific legacy and the profound influence he had on generations of developmental biologists. The piece is available open access in Nature Communications: www.nature.com/articles/s41...

Reversibility, regulation, and the community of development: the legacy of Sir John B. Gurdon - Nature Communications

Nature Communications - Reversibility, regulation, and the community of development: the legacy of Sir John B. Gurdon

nature.com

We are honored to share our Perspective in Nature Communications, reflecting on the legacy of John B. Gurdon. Beyond his discoveries, his generosity and curiosity inspired a community of scientists-we remember and celebrate his lasting impact. #JohnGurdon #Xenopus #NatureCommunications

Reversibility, regulation, and the community of development: the legacy of Sir John B. Gurdon

Nature Communications - Reversibility, regulation, and the community of development: the legacy of Sir John B. Gurdon

rdcu.be

We are excited to share our new preprint: SMARCA2/4-Dependent Chromatin Remodelling Establishes Gene Regulatory Programs in Early Human Embryos and Blastoids. www.biorxiv.org/content/10.64898/2025.12.01.691499v1

Pls Repost: I am putting together an edition of “Methods in Molecular Biology” focused on early development, encompassing gastrulation. I am making a list of potential authors for chapters. If interested, please contact me - An excellent opportunity for trainees to co-author with their advisors.

No offense but I think we underestimate how many of our current problems, both cultural and political, are downstream of the decline in reading, the decline in learning and the loss of interest in the humanities.

Been there, done that!

Ming Tommy Tang@tommytang.bsky.social · 8mo ago

1/ One of the biggest hidden killer in bioinformatics? Not a bug. Not a crash. It’s the 0-based vs 1-based coordinate trap. A thread 🧵

Anthony A. Hyman will become EMBL’s next Director General. He joins EMBL from @mpi-cbg.de in Dresden. He is also Professor of Molecular Biology @tudresden.bsky.social, and was a group leader at EMBL Heidelberg from 1993 to 1999. www.embl.org/news/people-...

Do you have an exciting new chromatin/transcription story that you'd like to share with the #FN community? Fill out this form to be considered for a talk in our Jan-June 2026 schedule! forms.gle/TBi38UgYxPAB... Please repost and share!

Application to speak in the Fragile Nucleosome series

Thank you for your interest in our seminar series! We use a variety of different session formats but, in general, trainees can plan for a ~15 min talk + 5min Q/A and PIs can plan for a ~25min talk +...

forms.gle

I'm guest-editing a collection on "Enhancer-promoter interactions" at Genome Biology. Please send us your exciting stories! link.springer.com/collections/...

Art class today. The theme was underwater, so I couldnt resist painting my model organism #Xenopus laevis (African clawed frog). This is done in encaustics, which is a mixture of beeswax and resin 🐸 #Art #SciArt 🧪

www.embopress.org/doi/full/10....

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)

AI has so much potential for interpreting biological images, and yet, annotated biological datasets needed to train AI tools remain scarce. If you generate microscopy data or develop AI tools to interpret it, check it these new guidelines: www.ebi.ac.uk/about/news/t... #bioimaging #microscopy 🧬🔬

What do you know about version control?🔁 It’s how researchers keep their projects organized, track every change, and never lose work again. Self-Paced Tutorial of the Day: Introduction to Version Control within RStudio ⚙️ lmu-osc.github.io/Introduction...

It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the @gurdoninstitute.bsky.social Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r

A good day to remember John Gurdon’s school report from his biology master at Eton

Dr. John Gurdon, a British biologist and Nobel laureate who in the early 1960s introduced a paradigm-shifting method of cell manipulation that led to the world’s first cloning of a large mammal, a sheep named Dolly, died on Tuesday at 92.

John B. Gurdon, 92, Dies; Nobelist Paved Way for Cloning of Animals

His work in the manipulation of cells laid the foundation for stem cell biology and regenerative medicine and led to the first cloned large mammal, a sheep named Dolly.

nyti.ms

🚀 #NAKO Launches the Pilot Phase of Its Trusted Research Environment 📝 Health-focused companies can now apply for secure, GDPR-compliant access to Germany’s largest long-term population health data. 👉 Read more: t1p.de/q0i64 @nako.de #HelmholtzMunich #DataProtection #HealthResearch

Very excited to share an excellent review from @teresa-urli.bsky.social, published one week before her PhD defense! We did a deep dive into the fascinating biology of the variant Polycomb complex, PRC1.6 (1/5) journals.plos.org/plosgenetics...

Epigenetic relay: Polycomb-directed DNA methylation in mammalian development

In mammals, repression of germline-specific gene expression is essential for preserving somatic cell identity and preventing disease. Germline gene silencing is often dependent on the presence of prom...

journals.plos.org

Do not forget to apply to the FEBS Advanced Lecture Course: 6th Danube Conference on Epigenetics (19–22 October 2026, Budapest, Hungary. Will be a great meeting as always. Check out the site: network.febs.org/posts/febs-a...

FEBS Advanced Lecture Course: 6th Danube Conference on Epigenetics

The FEBS Advanced Lecture Course: 6th Danube Conference on Epigenetics will take place 19–22 October 2026 in Budapest, Hungary. Here we give a taste of the scientific content, flag some of the speaker...

network.febs.org