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Andy Pekosz

@andrewpekosz.bsky.social

interested in respiratory viruses, primary cell cultures, virus evolution, cocktails, craft beer and soccer...order changes daily!

146 Posts758 Follower150 Folgt
Andy Pekosz@andrewpekosz.bsky.social · 2mo ago

our work on influenza B virus from 2024-25. HA antigenic drift and reassortment between IBV clades drove the emergence of this new C.3.1/re variant. Still a lot of research to do on the virus. @ceirrnetwork.bsky.social provided funding @johnshopkinsmmi.bsky.social journals.asm.org/doi/10.1128/...

Emergence of an antigenically drifted and reassorted influenza B virus at the end of the 2024–25 influenza season | mBio

Influenza B viruses are undergoing a period of antigenic and genetic expansion, with several reassorted viruses emerging that also contain point mutations in key hemagglutinin antigenic sites proximal...

journals.asm.org

Andy Pekosz@andrewpekosz.bsky.social · 2mo ago

another great collaboration across the Johns Hopkins CEIRR teams. this is about the IAV work we did that season...our IBV work was characterized in another manuscript i'll post about shortly. Thanks to @ceirrnetwork.bsky.social for the support and to the study enrollees who made this possible.

Dept of Molecular Microbiology & Immunology at Johns Hopkins@johnshopkinsmmi.bsky.social · 3mo ago

Collaboration between @jhu.edu @hopkinsmedicine.bsky.social & @johnshopkinssph.bsky.social @andrewpekosz.bsky.social The 2024-25 flu season = high cases & hospitalizations Serum neutralization & virus genomics help capture what drove season in Balt MD @jidjournal.bsky.social paper bit.ly/45ROJK4

Nonia Pariente@npariente.bsky.social · 4mo ago

Aging has effects that reshape the immune system in unique, sex-specific ways, but these differences are rarely taken into account (& most research is on males) An Essay @plosbiology.org argues that accounting for both sex and age is essential to advance personalized medicine plos.io/4wkqdgd 🧪

The problem with one-size-fits-all medicine: Biological sex and the aging immune system

Aging has effects on the immune system that are similar in men and women, but also reshapes their immune systems in unique, sex-specific ways, however these differences are rarely taken into considera...

plos.io

Andy Pekosz@andrewpekosz.bsky.social · 4mo ago

Such an honor to be involved with International Society for Respiratory Viruses and the planning for #OptionsXIII . If you are interested in influenza and other respiratory viruses, come to our meeting as registration is open: www.isrv.global/news/in-the-...

In the Spotlight: Dr Andrew Pekosz - ISRV

Co-chair of the Options XIII Conference for the Control of Influenza, Dr Andrew Pekosz is Professor and Vice Chair in the Department of Molecular Microbiology and Immunology at the Johns Hopkins Bloom...

isrv.global

Andy Pekosz@andrewpekosz.bsky.social · 5mo ago

Very sad to hear about the passing of Bernard Roizman. A real powerhouse in virology whose trainees are numerous and many have also had a profound impact on virology: www.annualreviews.org/content/jour...

The Maturation of a Scientist: An Autobiography

I was shaped by World War II, years of near starvation as a war refugee, postwar chaos, life in several countries, and relative affluence in later life. The truth is that as I was growing up I wanted ...

annualreviews.org

Andy Pekosz@andrewpekosz.bsky.social · 6mo ago

Had a great session on virology and pathogenesis at the H5N1 preparedness forum here in downtown DC. @angierasmussen.bsky.social and I covered a wide range of topics...i had a blast and i think we were very informative as well (no slides!!!)

Angie Rasmussen@angierasmussen.bsky.social · 6mo ago

Busy day...after I talk about sex and viruses in Vienna, I'll be talking about bird flu and pandemic preparedness with @andrewpekosz.bsky.social and Erin Sorrell in DC. If you are in the nation's Capitol, you should join us! www.eventbrite.com/e/johns-hopk...

Andy Pekosz@andrewpekosz.bsky.social · 8mo ago

always a pleasure to be a guest on @publichealthpod.bsky.social , though its usually because some respiratory virus is running amok. this is episode 995 and i'm hoping i get a chance to be on #1000!

Public Health On Call Podcast@publichealthpod.bsky.social · 8mo ago

Flu is surging in states across the country. @andrewpekosz.bsky.social talks about the new strain that’s driving cases, why getting a flu shot can still protect you, and how antivirals can help if you do get sick. podcast.publichealth.jhu.edu/995-a-record...

Promo graphic for Public Health On Call episode 995, titled A Record-Breaking Flu Season. Additional text reads: Andrew Pekosz on the new strain that's driving cases, why getting a flu shot can still protect you, and how antivirals can help if you do get sick.
Elizabeth Jacobs, PhD@elizabethjacobs.bsky.social · 10mo ago

The anti-vaccine movement has the same talking points now as it did in the 1800’s. It’s always been a rejection of science, scientists, and progress, with a soupçon of paranoia. Below is a slide for a talk I’m preparing that illustrates the identical strategies. I have more examples, too.

Slide with the title “The anti-vaccination movement has no new material”. Montague R. Leverson, Lawyer, Liar, Quack 1895 Robert F. Kennedy, Lawyer, Liar, Quack 2025 Accuse expert vaccine advisory committees of pro-vaccine "bias" "That commission was deliberately packed at its very outset..." "The committee has been plagued with persistent conflicts of interest and has become little more than a rubber stamp for any vaccine". Falsely state that vaccines cause death "Vaccination has caused more deaths and diseases than ever has smallpox". "This [COVID19 vaccine] is the deadliest vaccine ever made..." Claim that healthcare practitioners and scientists are only in it for the money, not because of scientific evidence "...Jenner was a mercenary charlatan whose ignorance and impatience of scientific methods were equaled only by his mendacity..." "Doctors are being paid to vaccinate, not to evaluate. They're pressured to follow the money, not the science". Use false and inflammatory words about vaccines The "Blood-poisoning process of vaccination" "They went on a search... looking for the most toxic things that they could find...to
Andy Pekosz@andrewpekosz.bsky.social · 10mo ago

A new preprint from the lab led by PhD student Elgin Akin is up at medRxiv: www.medrxiv.org/content/10.1... 1/6

In-vitro characterization of 2019-24 Influenza B Viruses reveals increased temperature-dependent fitness in later timepoints independent of antigenic drift

Seasonal influenza viruses continually acquire mutations that can alter both their replication efficiency and antigenic properties. While recent seasonal Influenza B viruses (IBV) are characterized as...

medrxiv.org

Dr. Michael D. L. Johnson@copperbae.bsky.social · 11mo ago

I do biomedical research to help people. When people come in this space making things up, it makes it harder for people not in the field to trust the extensive studies that we do and distinguish fact from fiction. Baseless claims reduce future cures. Willful ignorance drives us backwards.

Dept of Molecular Microbiology & Immunology at Johns Hopkins@johnshopkinsmmi.bsky.social · 12mo ago

A profile in @jhu.edu's HUB highlights JH-CEIRR's @ceirrnetwork.bsky.social important influenza research, led by co-directors @johnshopkinssph.bsky.social virologist & professor @andrewpekosz.bsky.social & @hopkinsmedicine.bsky.social Richard Rothman, MD More here: hub.jhu.edu/2025/09/10/j...

JHU Center of Excellence leads global fight against influenza

Experts at Johns Hopkins and across the country work together to better understand the behavior and characteristics of respiratory viruses, how our immune system responds to them, and how we can preve...

hub.jhu.edu

Andy Pekosz@andrewpekosz.bsky.social · last yr.

Found this book in my department mailbox yesterday. No envelope, no shipping information, no note and I was the only person to receive this "gift". Clearly, someone needs to come to my lecture on the origin and evolution of the COVID-19 pandemic to get educated on the facts.

Bild