Andrew Zalesky
@andrewzalesky.bsky.social
www.sysneuro.org Melbourne, Australia
Computing correlations between brain maps? Check out our new tool for fast p-value estimation for spatial brain map correlations Fast alternative to the spin test, eigenstrapping, BrainSMASH github.com/yuanzhel94/SPICE
bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 6mo agoSPICE: Fast parametric inference of significance for spatial associations between brain maps https://www.biorxiv.org/content/10.64898/2026.03.08.710410v1
Are connectome-based network mapping methods and the >200 papers that have used it invalid? New paper out in @NatureNeuro says YES. nature.com/articles/s41... I have concerns about this new paper's methods and conclusions, but am biased. What do others think?
Investigating the methodological foundation of lesion network mapping - Nature Neuroscience
The lesion network mapping method links diverse brain lesions to similar functional brain networks, reflecting general brain organization rather than disorder-specific circuits.
nature.com
If you are planning to go to OHBM 2026 this year, consider attending the pre-conf Brain Connectivity Workshop, celebrating our 25th year! @ohbmofficial.bsky.social www.bcw2026.org
BCW 2026: June 10-12
bcw2026.org
My paper reviewing how different neurodegenerative diseases affect autonomic function was just published.
Nature Reviews Neuroscience@natrevneuro.nature.com · last yr.Autonomic dysfunction in neurodegenerative disease — a Review by Mara Mather www.nature.com/articles/s41... @maramather.bsky.social #neuroscience
Absolutely incredible work by Davide Momi, John Griffiths,and a stellar team of neuroscientists with a multidimensional view of brain dynamics. This work gives us a WHOLE BRAIN map of excitability. www.nature.com/articles/s41...
Stimulation mapping and whole-brain modeling reveal gradients of excitability and recurrence in cortical networks - Nature Communications
How brain networks organize and interact based on their hierarchical position remains poorly understood. Momi, Wang et al find that high-order brain networks show stronger responses to stimulation and...
nature.com
Happy to share that our article “Human lifespan changes in the brain’s functional connectome” is now published online at Nature Neuroscience @natureneuro.bsky.social ! Many thanks to all collaborators & data contributors, and the editor team & reviewers! www.nature.com/articles/s41...
Human lifespan changes in the brain’s functional connectome - Nature Neuroscience
Sun et al. report human lifespan changes in the brain’s functional connectome in 33,250 individuals, which highlights critical growth milestones and distinct maturation patterns and offers a normative...
nature.com
When we use TMS to treat depression, we think it alters neural activity in a deep brain structure known as the subgenual anterior cingulate (sgACC). But this is hard to test directly, until our preprint with @coreykeller.bsky.social, @neuro-engineer.bsky.social, Nick Trapp, and Aaron Boes (UIowa) 1/
DLPFC Stimulation Suppresses High-Frequency Neural Activity in the Human sgACC
Transcranial magnetic stimulation (TMS) to the dorsolateral prefrontal cortex (DLPFC) is hypothesized to relieve symptoms of depression by inhibiting activity in the subgenual anterior cingulate corte...
biorxiv.org
Study human brain structure and function with our new open access 7T MRI dataset led by superstar scientist @donnagift.bsky.social ↙️
Donna Gift Cabalo@donnagift.bsky.social · last yr.Our open-source multimodal precision MRI dataset is officially out! 🧲🧠🧲 www.nature.com/articles/s41... osf.io/mhq3f/ @borismontreal.bsky.social @jroyer.bsky.social @themindwanders.bsky.social @jordandekraker.bsky.social
🚨We're hiring another tenure-track at McGill University: focus on brain-body science! 👇 mcgill.wd3.myworkdayjobs.com/en-US/mcgill...
SAVE THE DATE 2025 OHBM Oz meeting November 12, 2025 Melbourne
OHBM Australia@ohbm-australia.bsky.social · last yr.🚨 We are excited to announce that the next OHBM Australia meeting will be in Melbourne on Wednesday, 12th November, 2025! Stay tuned for more details 👀
We are hiring! We're looking for a Research Office to help out with recruitment & assessment on a large-scale study looking at the relationship between brain imaging measures and psychopathology. Please forward this link to anyone who might be interested: careers.pageuppeople.com/513/ci/en/jo...
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📢 Exciting news! OHBM is partnering with United Airlines for our upcoming event. Enjoy special rates on flights to Brisbane, Australia, from June 21 to July 1, 2025. For more information, visit the link in comments! #OHBM2025 #TravelwithUnited
June 2025 is an exciting month for Psychological and Brain Sciences in Australia! In addition to our joint meeting between EPC and APCV, the Organisation for Human Brain Mapping meets in Brisbane the following week. See below for a schedule of events linked with OHBM.
Andrew Zalesky@andrewzalesky.bsky.social · 2y agoCheck out the schedule of events linked with OHBM 2025 - Brain connectivity workshop, June 20-22 - Hackathon, June 21-23 - Neurodesk, June 21 - Brain gradients, June 23 - Precision network therapeutics, June 29 Register now! We look forward to welcoming you to Brisbane! @ohbmofficial.bsky.social
How is the body experienced in mental health conditions? 🧠🫀🫁 Our (@gabmackie.bsky.social) new paper in eClinicalMedicine explores lived experiences and patient priorities for interoception research. 🧵1/n www.sciencedirect.com/science/arti...
ScienceDirect.com | Science, health and medical journals, full text articles and books.
authors.elsevier.com
Workshop contributors had a variety of initial thoughts in response to the question: “how are bodily signals related to your mental health?” This was conducted prior to any detailed information about the aims of the workshop, or the field's perceived notions of interoception. 🧵4/n
Myelinated fiber labeling and orientation mapping of the human brain with light-sheet fluorescence microscopy | bioRxiv www.biorxiv.org/content/10.1...
Getting excited about OHBM25. Not far now! Features an AMAZING schedule of keynotes, educational workshops, symposia, networking events as well as several satellite meetings! Don't forget to register before April 15 for the EBR! @ohbmofficial.bsky.social www.humanbrainmapping.org/i4a/pages/in...
The brain-heart connection: Shared Pathways of Brain and Cardiovascular Health medicalxpress.com/news/2025-02... www.jneurosci.org/content/45/8...
We've updated our mouse connectome-based ID paper using simultaneous Ca2+ imaging and fMRI connectivity data--check it out! www.biorxiv.org/content/10.1... Shoutout to all! @francimandi.bsky.social, @toddc.bsky.social, @mallarchak.bsky.social, @richardfbetzel.bsky.social, and many others! 1/2
Multimodal identification of the mouse brain using simultaneous Ca2+ imaging and fMRI
Individual differences in neuroimaging are of interest to clinical and cognitive neuroscientists based on their potential for guiding the personalized treatment of various heterogeneous neurological c...
biorxiv.org
Ever heard of EEG microstates? Usually defined as cluster centres of topography, the dynamics of MS sequences are referred to as "syntaxes". Our new review discusses syntax methods and show how they could be better associated with the underlying EEG signal: 🧵👇 www.sciencedirect.com/science/arti...
Nature Physics Topology shapes dynamics of higher-order networks www.nature.com/articles/s41...
Topology shapes dynamics of higher-order networks - Nature Physics
Higher-order interactions reveal new aspects of the interplay between topology and dynamics in complex systems. This Perspective describes the emerging field of higher-order topological dynamics and d...
nature.com
For data defined on top of a graph/network (e.g. annotations on brain graphs), it is efficient to decompose them with filters that adapt to the spectral characteristics of the data at hand | w. @dimitrivdv.bsky.social @rikossenkoppele.bsky.social + C-F Westin
arXiv eess.SP Signal Processing@eesssp-bot.bsky.social · 2y agoHarry H. Behjat, Carl-Fredrik Westin, Rik Ossenkoppele, Dimitri Van De Ville: Signal-adapted decomposition of graph signals https://arxiv.org/abs/2502.11845 https://arxiv.org/pdf/2502.11845 https://arxiv.org/html/2502.11845
So much research focusses on using brain connectivity to predict an individual's cognition, IQ, disease status, etc. BUT what about the inverse problem? Can personal data be used to build an individual's whole connectome? YES - with AI: www.biorxiv.org/content/10.1...
🚀 Explore Spectral Normative Modeling in action! We’ve built an interactive visualization showcasing high-resolution normative reference ranges generated via SNM. 🔗 Try it here: sina-mansour.github.io/normative_br...
sina-mansour.github.io
Sina Mansour L.@sinamansourl.bsky.social · 2y ago1/ Excited to share our latest preprint! 🚀 We introduce Spectral Normative Modeling (SNM)—a novel approach leveraging graph spectral methods to advance brain charting towards personalized precision medicine. 🔗 www.medrxiv.org/content/10.1...
TMS is delivered to the DLPFC in depression to modulate SGC activity But axons linking DLPFC and SGC are absent. How then does TMS stimulation delivered to the DLPFC modulate SGC activity? Check out Caio's work on how stimulation effects propagate in the absence of direct anatomical paths
Rick Betzel@richardfbetzel.bsky.social · 2y agoCaio is having a good day. Another preprint on which he's first author -- this time, describing pathways through the connectome for indirectly stimulating subgenual cingulate cortex in the context of depression. Neuroanatomical pathways of TMS therapy for depression www.medrxiv.org/content/10.1...
Can damage to a specific brain circuit cause psychosis? New paper out today by @andrewpines.bsky.social @shansiddiqi.bsky.social says Yes! Hub of the circuit is in the hippocampus - great alignment with NMDA encephalitis. @braincircuits.bsky.social
Andrew Pines@andrewpines.bsky.social · 2y agoWhat brain regions are involved in causing psychotic symptoms? Take a moment away from the existential dread about the future of science, and join me in this summary of some incredibly cool stuff that could help patients! 1/n🧵
Synaptome architecture shapes regional dynamics in the mouse brain | www.biorxiv.org/content/10.1... Led by Justine Hansen Big news: there are all sorts of different synapse types in the brain 👀‼️⤵️
9/ 🚨 But there’s more! SNM reveals the heterogeneity in cortical atrophy among AD patients. AD patients are not only different from healthy individuals but also highly diverse among themselves, beyond the conventional findings of group/subtype-level studies.
