Artur
@arturruppel.bsky.social
Postdoc @InstitutPasteur | Using minimalistic tissue models to understand how cell-scale mechanics give rise to collective behavior | Micropatterning, Traction Force Microscopy, optogenetics & Python tools
New paper in @natphys.nature.com! We uncovered a stress adapation mechanism where keratin intermediate filaments in stretched epithelia undergo a supracellular bundling transition that uncages the nucleus. www.nature.com/articles/s41... @ibecbarcelona.eu, @upc.edu @qmul.bsky.social
Nice paper from Ruppel et al. in @natphys.nature.com www.nature.com/articles/s41...
A minimal in vitro assay for cell intercalation highlights the importance of interfacial tension and migratory forces - Nature Physics
Cell intercalation is an exchange of cell neighbours. Now it is shown in a minimal system of four cells that intercalation is driven by junction tension and migratory forces.
nature.com
New Toettchlab paper alert! Harrison Oatman just published his beautiful work combining software design for "smart" microscopy+optogenetics and some really beautiful work understanding EGFR-driven collective cell migration. www.cell.com/cell-systems...
Our latest work on shape-programmable tissues is out in @science.org. By positioning topological defects in cellular nematics, we encode frustrated 2D force fields that relax into predictable 3D shapes. Collaboration with Marino Arroyo’s lab, led by @pauguillamat.bsky.social at @ibecbarcelona.eu.
We had covered the history of traction force microscopy (TFM) earlier: bsky.app/profile/epim... But what about applying TFM into more physiologically relevant systems, such as those in 3D? I am @barrasa-fano.bsky.social and I'll be your guide through this thread on #3DTractionForceMicroscopy.
I'm happy to present our new tool, EpiCure, a napari plugin to ease correction of segmentation and tracking of epithelia movies, developed in @devstempasteur.bsky.social
napari 0.7.0 is available now! 🚀🎉 It's a BIG release so read the full release notes, with highlights: napari.org/stable/relea... We want to thank everyone who has worked incredibly hard on this release including our 11 new brilliant contributors 🤩 and the community for their support and feedback!
napari 0.7.0
Mon, Mar 23, 2026 We’re happy to announce the release of napari 0.7.0! napari is a fast, interactive, multi-dimensional image viewer for Python. It’s designed for browsing, annotating, and analyzing…
napari.org
Faure, L. M., Gómez‐González, M., Baguer, O., Comelles, J., ... & Roca‐Cusachs, P. (2024). 3D Micropatterned Traction Force Microscopy: A Technique to Control 3D Cell Shape While Measuring Cell‐Substrate Force Transmission. Advanced Science, 11(46), 2406932. #EpithelialMechanics buff.ly/Mpt1o3g
Now published in @natcomms.nature.com! 🥳 👉 rdcu.be/eATn3 We developed image analysis tools to capture the nematic orientation field of 3D tissue surfaces. Tested on epithelial aggregates, zebrafish hearts, myoblasts on spheres & micro-vessels, we combined soft matter physics with exp. biology.
First paper as first & corresponding author, out in PLOS Computational Biology! 🎉 napariTFM brings traction force & monolayer stress microscopy into napari, accessible via GUI; open-source, validated and no coding required. 😉 Check it out 👇
Our next #ForceTalk is with Prof Sylvain Gabriele @sgabriele.bsky.social exploring "Mechanosensing of epithelial cells: curvature, confinement and memory" 📅 4 March 2026 🕒 15:00 - 16:00 GMT Online & open to all 👉 www.kcl.ac.uk/events/force... #mechanobiology @kingsnmes.bsky.social
Just a few days left for this application deadline!
Ishier Raote@ishier.bsky.social · 6mo agoPostdoc job alert at Institut Jacques Monod in Paris! Interested in fundamental membrane trafficking? We seek a postdoc to study collagen secretion as a model for core principles of how cells and their environment build each other. emploi.cnrs.fr/Offres/CDD/U...
