Bhaskar Naidu, Vera Lillo, Manneville, Miserey, @felixmendu.bsky.social et al. show that extracellular mechanical forces reciprocally regulate #Golgi function. The study reveals a feedback pathway by which Golgi export supports cell spreading and mechanoadaptation. rupress.org/jcb/article/...
Adam Wołowczyk
@awolowczyk.bsky.social
🩺 FY1 Doctor in Kent 🎓 MB BChir @uniofcam.bsky.social 🥼 MSci Gershlick lab @thecimr.bsky.social Interests include fluorescence microscopy, organelle dynamics & biophysics
1/ The world's songbirds sing in just 8 basic sounds. And where a bird lives decides which ones it uses. My first PhD paper is out now in @science.org (www.science.org/doi/10.1126/science.aee6239) Here is what we found:
So cool to finally see this!
At membrane contact sites, bridge-like transport proteins, e.g. LPD-3, mediate bulk lipid transfer between cellular organelles. @nature see cryo-EM structure of native LDP-3, and gain insights into its functioning and interaction with other proteins and lipids. shorturl.at/lycuz & shorturl.at/ARpUK
I'm delighted to be hosting the Cambridge University Endocrinology Society's annual conference this Friday, entitled: 'From Bench to Bedside (and back again)'. We're really fortunate to have such an exciting line up of speakers, integrating across a wide range of career stages and fields.
De novo design of transmembrane fluorescence-activating proteins www.nature.com/articles/s41...
De novo design of transmembrane fluorescence-activating proteins - Nature
A study describes the design of de novo ligand-binding transmembrane proteins, demonstrating their specific binding and activation of fluorogenic ligands.
nature.com
ÅNGSTRÖM-RESOLUTION IMAGING OF CELL-SURFACE GLYCANS 🧬🎨🍬 The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy www.biorxiv.org/content/10.1...
It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density, which usually isn’t attainable. Lipid-CLEM brought to you by @mathilda95.bsky.social changes that. www.biorxiv.org/content/10.1...
UK Membrane Trafficking 2024 Who doesn’t like a deadline that gets brought forward? Please register by 3rd December - King’s need longer to make the sandwiches than I previously thought! estore.kcl.ac.uk/conferences-... Programme coming soon!
UK Membrane Trafficking Meeting 2024 | King's College London eStore
Registration for the 2024 UK Membrane Trafficking Meeting, held at KCL.  Registration per person, to include sandwich lunch and coffee breaks and even
estore.kcl.ac.uk