This one is really important. Great work! Some papers don't go on the reading list, you open them right away. 🤓 I can't help but wonder whether there's another level of regulation via acyl chain identity... the PS threshold should highly depend on saturation degree.

Abdou Rachid Thiam@abdourachidthiam.bsky.social · 7h ago

A long-standing mystery in cholesterol biology: why is ER cholesterol sensing so switch-like rather than gradual? Our answer: cholesteryl ester phase separation in the ER membrane, which converts small lipid changes into a cooperative transcriptional response. www.biorxiv.org/content/10.6...

Great Stuff from Scotty & crew!

@tafesselab.bsky.social · yesterday

To understand what a lipid does, we need to know its partners. Which proteins bind lipids and how can we capture those interactions? Our new Nature Protocols paper provides a practical, step-by-step guide to identifying lipid-binding proteins. 🧵

New preprint alert!!! Super proud to finally share an authentic 'tour-de-force' from the amazing PhD students Shivani Gunnan @shivanigunnan.bsky.social, Max Kotz and Lucas Ribas, in collaboration with @friedrich-group.bsky.social 👇a small thread www.biorxiv.org/content/10.6...

Developmental growth rates adapt to enable self-correction of organ morphology after injury.

Proportional organ growth requires tissue-level control of cell behavior. Yet the cues that adapt growth rates, especially after organ injury, remain unclear. Here, we uncover that developing organs a...

biorxiv.org

We are happy to present a new paper on gene regulation on the way to regenerating the spinal cord www.biorxiv.org/content/10.6... 🧵 1/4

Baseline regulatory programs in larval and adult neural progenitors converge towards an injury-induced state after spinal cord injury

Regeneration after spinal cord injury requires progenitor cells to convert injury-associated signals into coordinated remodeling of gene regulatory programs. Mammalian spinal progenitors show limited ...

biorxiv.org

These are really cool stories - do give them a look!

@paveltomancak.bsky.social · 2d ago

#Twisting embryos and multiple #attachment sites in #Drosophila - now both available as #preprints. Proud of @giuliaserafini.bsky.social & @cuencam15.bsky.social, who worked together & established theory collaborations with @lepuslapis.bsky.social & @carldmodes.bsky.social @mpi-cbg.de at its best

Can confirm. The sight of a Dimroth condenser taking flight like a rocket ship and shattering under the fumehood roof is really something.

Dr. Emily Arndt 🏳️‍⚧️@brachinus.bsky.social · 5d ago

even the tamer acrylate/methacrylate monomers are scary as shit when they kick off. I have seen things with BP >200 C go from RT to boiling in a fraction of a second

How exciting to get an email that starts with "We are pleased to inform you that..."!!! 🥳 I am grateful to receive two years of research funding from the American Heart Association to unravel the intricacies of phospholipid scrambling by TMEM16F that plays an important role in blood clotting.🩸

Check out this comprehensive proteomics study led by @cookkate.bsky.social, @nadlerlab.bsky.social and colleagues using panels of bifunctional lipids to map differential lipid-protein interactome networks! #lipidtime

André Nadler@nadlerlab.bsky.social · last wk.

Lipids build the membranes of all cells, but identifying their precise functions is extremely challenging. Here’s our attempt to change that: How to find and understand lipid-protein interactions, by Katelyn Cook & company. www.biorxiv.org/content/10.6...

Our new paper on lipids in neural stem cell aging!! Congratulations to Xiaoai Zhao for her fantastic work! ✨🥂 www.science.org/doi/10.1126/...

Lipidomic profiling reveals age-dependent changes in plasma membrane lipids that affect neural stem cell aging

Plasma membrane lipids are remodeled with age in neural stem cells, and rejuvenating membrane lipids boosts old cell function.

science.org

A minimal lipid kinase/phosphatase system, two effector proteins from Legionella pneumophila, self-organizes together with its lipid substrates (PI/PI3P) into dynamic patterns on membranes. Check out our preprint: www.biorxiv.org/content/10.6...

Explore how Expansion-dSTORM resolves unresolvable cellular structures in our new papers: • 8-nm microtubule periodicity, clathrin lattices & NUP96 dimers • Presynaptic vesicle docking sites (40-nm Munc13-1/RIM rings) All using unmodified cells & standard immunolabeling: ▶️ rdcu.be/fwBYY

#lipidtime

André Nadler@nadlerlab.bsky.social · last wk.

Lipids build the membranes of all cells, but identifying their precise functions is extremely challenging. Here’s our attempt to change that: How to find and understand lipid-protein interactions, by Katelyn Cook & company. www.biorxiv.org/content/10.6...

André and his group are going places. I am very proud of my colleague and friend. @mpi-cbg.de Science at its best.

André Nadler@nadlerlab.bsky.social · last wk.

Lipids build the membranes of all cells, but identifying their precise functions is extremely challenging. Here’s our attempt to change that: How to find and understand lipid-protein interactions, by Katelyn Cook & company. www.biorxiv.org/content/10.6...

ANNNNND introducing the amazing Katelyn @cookkate.bsky.social on bluesky... She finally made an account!

André Nadler@nadlerlab.bsky.social · last wk.

Lipids build the membranes of all cells, but identifying their precise functions is extremely challenging. Here’s our attempt to change that: How to find and understand lipid-protein interactions, by Katelyn Cook & company. www.biorxiv.org/content/10.6...

😱🤩 wow! Shining light on lipid-protein interactions #lipidtime Monumental work and awesome skytorial @nadlerlab.bsky.social Very excited to dig through the preprint. Congratulations already 🎉

André Nadler@nadlerlab.bsky.social · last wk.

Lipids build the membranes of all cells, but identifying their precise functions is extremely challenging. Here’s our attempt to change that: How to find and understand lipid-protein interactions, by Katelyn Cook & company. www.biorxiv.org/content/10.6...

Lipids build the membranes of all cells, but identifying their precise functions is extremely challenging. Here’s our attempt to change that: How to find and understand lipid-protein interactions, by Katelyn Cook & company. www.biorxiv.org/content/10.6...

Very happy to see this #MechanoGolgi story out (and in full open access, thanks to @upf.edu). Thanks a lot to everyone who contributed and helped make this possible, and, hopefully, more to come! rupress.org/jcb/article/...

Felix Campelo@felixmendu.bsky.social · 11mo ago

🧵 I've been meaning to write a #Skytorial on our recently posted prepring in which we show evidence that the Golgi 🥞 is a mechanoresponsive organelle. Extracellular mechanical forces also tune Golgi export capacity! 👉 www.biorxiv.org/content/10.1...

Excited to share our new preprint! 📄 We introduce cTRP PicoRulers as programmable reference standards for benchmarking sub-10 nm fluorescence microscopy. From dSTORM over DNA-PAINT to Expansion Microscopy - one platform, many applications.🔬 👉Read it here: www.biorxiv.org/content/10.6...

A question: does anyone know about communities or groups for scientists who are committed to writing without the use of LLMs / genAI?

Rest in peace, Pavel. You were an inspiration to all of us and I still cannot comprehend that you are not there anymore. This is a heavy blow for Science and we will sorely miss your joy & enthusiasm, your dedication to scientific excellence and your belief in a bright future.

IOCB Prague@iocbprague.bsky.social · last wk.

IOCB Prague is deeply saddened to announce that on Thursday 23 July 2026, our outstanding colleague, teacher, mentor and friend, Prof. Pavel Jungwirth, tragically passed away. May his memory be a blessing.

On my way to FASEB SRCs Lipid Droplets & Phospholipids. This will be quite the journey but cannot wait to meet the crew!

Gerry Hammond@gerryhammond.bsky.social · 2w ago

2 days until @FASEB Phospholipids! Can't wait to see everyone and nerd out for a week of lipid and membrane biology 🙌

I would like to congratulate Derek Lowe on his promotion to editor of Science (at least that's what everyone seems to be calling him). An exciting next chapter for the former major league pitcher turned medicinal chemist.

A new, rather unexpected glycolipid class. Very well done study. Given how they look structurally, I think it makes a lot of sense to test these lipids against a panel of GPCRs. Lipid biology keeps surprising me. I like that. www.biorxiv.org/content/10.6...

Nothing to add

NordenLab@nordenlab.bsky.social · 2w ago

I know I am shouting into a void here as the people doing it are not on this platform...Dear applicants, I know what my homepage says, I wrote it. If you want to apply to my lab, please tell me in your own words WHAT you are excited about and why. I will be excited with you and we can discuss...!

Our @jcellsci.bsky.social poster article “The nucleus-vacuole junction at a glance” is out! Big thanks to @abbybuch.bsky.social and @luskinglab.bsky.social for organizing an amazing special issue “Cell biology of the nucleus”. #ContactSites journals.biologists.com/jcs/article/...

The nucleus–vacuole junction at a glance

Summary: The nucleus–vacuole junction is a prominent contact site linking the nuclear ER and the yeast vacuole. We highlight the physiological implications and metabolic plasticity of this unique orga...

journals.biologists.com

I'm looking forward to presenting at the Physics of the Cell DGZ Focus Workshop! Join if you want to learn about a ratchet mechanism in cell division!

DGZ.bsky.social@dgz.bsky.social · 3w ago

Join us on July 21 at noon for the next #DGZ #FocusWorkshop on #PhysicsOfTheCell, organized by @lmoeckl.bsky.social and @lepuslapis.bsky.social. Topics include mechanics of reproduction, glycan atlassing, embodied computation in ciliates, and physics of cell division @alisonkickuth.bsky.social

☀️Our July issue's out! Cover: #lysosome #metabolite 👉Editorial: #StemCell #embryo models 👉Perspective: #proteomics in #oocytes & embryo 👉Review: #ferroptosis in glial #tumors 🔬 #mitochondria #cytoskeleton #chromatin #BreastCancer #PhaseSeparation #lipids & more! www.nature.com/ncb/volumes/...

This is very cool. I really like it for reasons. 😉

Vanni Lab at UNIFR, Switzerland@labvanni.bsky.social · last yr.

Happy to share the latest work from the lab, led by @mudgal17.bsky.social‬, in collaboration with the Weis lab @ethzurich.bsky.social. How do nuclear membranes fuse during NPC assembly? We answer this question in our latest work, where we identify a new mechanism for membrane fusion… (1/13)

I have two post doctoral positions available in my lab funded by the Wellcome Trust to develop new chemical biology approaches to studying mitochondria. Would suit those with interest in both mitochondria and chemical biology. Advert below-please forward and repost! www.cam.ac.uk/jobs/researc...

Both articles are back, according to 'Retraction Watch'. Springer Nature un-retracts Planck papers, citing “human error” -> retractionwatch.com/2026/07/07/s...

Springer Nature un-retracts Planck papers, citing “human error”

Max Planck Today the Retraction Watch list of Nobelists who have retracted papers bids Verabschiedung to Max Planck. After days of scrutiny, Springer Nature has restored two papers by Planck, who w…

retractionwatch.com