Spinning spheroids on 40 µm circular patterns. Recent work from @olivierpertz.bsky.social lab!

🔬🧠 Our paper on smart microscopy & the issue of interoperability! www.biorxiv.org/content/10.1... LONG THREAD WARNING: Smart microscopy uses real-time image analysis to automatically guide the acquisition or perturbation of the sample (closed feedback-control loop). Many applications exist:

Automated optogenetic control of hundreds of cells in parallel. Each cell is individually steered, collectively acting as a "tissue printer". Preprint & code out! www.biorxiv.org/content/10.1...

PREPRINT OUT ✨ "hack" your microscope to work as a 3D printer! print micrometer sized features at cm scale. a method for easy and cheap microfabrication, with a focus on biological applications. THREAD ↓ www.biorxiv.org/content/10.1...

Time to build up my network after switching here 😁 It's the occasion to share one of my older images for #FluorescenceFriday here! The image shows a massive Boa Constrictor cell culture syncytium with cell membranes in gold, microtubules in cyan and nuclei in grey:) #sciart

Now that we’re on Bluesky, it’s a good time to bring back #badsciencedrawings – a collection of figures that prove that science is more science than art. Before Biorender, all we had was MS Paint and a dream. But ovals, lines, and lightning bolts were all we needed Morales-Botello et al., 2012

🚀 It's #FluorescenceFriday, and commissural axons are coming at you! 🧪🔬 15-hour time-lapse of chick commissural axons navigating and crossing the CNS midline (and reverse). One stack taken every 10 minutes. Pixels were color-coded in the z-axis. #LiveImaging #Neuroscience #Science #Microscopy 🧠✨

🔬 Calibrating the DMD for optogenetics. Project light on your cells by drawing in napari-pymmcore!

Mix two motors of opposite polarity with microtubules and they will partition space ! Microtubules will get organized in polar and active barriers, sorting the two motors in separated domains, leading to the emergence of a new type of patterns. #morphogenesis doi.org/10.1073/pnas... (1/n)

Polymerizing actin creates fireworks that are a sight to behold. This excitable medium produces polymerizing waves similar to those observed in other context. The parallels I tried to lay out in this perspective piece last year: tinyurl.com/53cbxm4v (LifeAct-GFP in Endothelial Cell)

I thought #fluorescencefriday would be a good opportunity for my first post here. Here are some crazy actin dynamics imaged with TIRF

This dance kills people! Human breast cells with a PI3K mutation showing coordinated cell movement.