I posted this a while ago. It is a very effective video!
Chise@sailorrooscout.bsky.social · 4mo agoHow Vaccines Work 🧬🧫🧪🔬💉🥽
Blake R Peterson
@blakerpeterson.bsky.social
Professor and Chair of Medicinal Chemistry at Ohio State; researcher at the interface of chemistry and biology, creating chemical tools for drug discovery https://pharmacy.osu.edu/directory/blake-r-peterson https://u.osu.edu/petersonlab/
Chise@sailorrooscout.bsky.social · 4mo agoMy quote of the day Science is the search for truth, that is the effort to understand the world: it involves the rejection of bias, of dogma, of revelation, but not the rejection of morality. Linus Pauling
Fly high, metal grandpa.
Crazy Train by Ozzy Osbourne ~ The Louisville Leopard Percussionists
YouTube video by LouLeopPerc
youtu.be
Robert McNees@mcnees.bsky.social · last yr.This morning I was explaining Ozzy Osbourne to them, doing the whole RIP tour of Black Sabbath and his solo stuff, and one of them said “Fly high, metal grandpa.”
I have no other way to say it. This paper blows my f@&!ing mind: www.science.org/doi/10.1126/...
In vivo CAR T cell generation to treat cancer and autoimmune disease
Chimeric antigen receptor (CAR) T cell therapies have transformed treatment of B cell malignancies. However, their broader application is limited by complex manufacturing processes and the necessity f...
science.org
This is a cumulative maximum intensity projection movie of the endoplasmic reticulum labeled with the membrane marker mEmerald-Sec61B.
The 2026 Chemistry Faculty Jobs List has 4 tenure-track positions: docs.google.com/spreadsheets... #facultychemjobs #chemsky #chemjobs
The 2026 Chemistry Faculty Jobs List
docs.google.com
“universities contributed patents underpinning 50% of FDA-approved drugs… NIH-funded basic science has contributed to the development of more than 90% of new medicines, vaccines, and devices… 75% of scientists in America were considering leaving the country.” www.statnews.com/2025/06/06/u...
We set out to quantify U.S. academic contributions to medicines. The results stunned even us
From 2020 to 2024, universities contributed patents underpinning 50% of FDA-approved drugs. 87% of those academic breakthroughs came from American institutions.
statnews.com
In a new Science study, cryo–electron tomography captures the in-cell architecture of the mitochondrial respiratory chain, illuminating how the coordinated action of molecular machines drives life’s fundamental energy conversion. Learn more in this week's issue: scim.ag/3FA3Ygq
A pie graph worth keeping in mind as the NIH budget plummets jamanetwork.com/journals/jam... for 356 new FDA drugs approved
Summary: 1st Ph3 readout for a #PROTAC; likely path-to-approval in metastatic breast cancer patients w/ ESR1 mutations after having received endocrine therapy & CDK4/6 inhibitors; in line with previous clinical data; stock brokers don‘t understand Ph1/2 data. www.fiercebiotech.com/biotech/pfiz...
Pfizer, Arvinas post mixed breast cancer survival results in first phase 3 test for a PROTAC degrader
Pfizer and Arvinas’ estrogen receptor (ER) degrader has
fiercebiotech.com
There’s a frequent perception among recent entrants to drug discovery world that if we could just find drug candidates faster, this will be a useful accelerant to the overall process. The issue is: this thinking is mostly (but not entirely) incorrect. 🧵 1/
Happy Holidays from the Peterson lab and the OSUCCC Drug Discovery Shared Resource HTS lab at Ohio State! @osucccjames.bsky.social
Super proud of Xiaojun Hu for a successful defense of his PhD in Pharmaceutical Chemistry (Medicinal Chemistry specialization)! Xiaojun was the first Ohio State graduate student to join my group after I moved here in 2019.
Americans are now one-third less likely to die from cancer at the same ages as Americans in 1990
Fluorescently labeled proteins are essential to research. But we should never forget how messed-up their behavior can be. An example from condensates:
Fluorescent Tags Are Basically Never Silent
science.org
“Scientists..found that those who often smoked, drank or ate processed meats were prone to accelerated organ aging, while anyone who regularly exercised or ate oily fish was far more likely to have youthful organs.” www.washingtonpost.com/wellness/202...
Inside your body, aging unfolds at remarkably different rates
New research shows aging is not a uniform process. Parts of our bodies start aging earlier than others, right down to our organs and cells.
washingtonpost.com
If you have a PC or Mac, with a Chrome browser, use Sky Follower Bridge to find the followers that you had on Twitter over here. It’s very easy to use ! chromewebstore.google.com/detail/sky-f...
Sky Follower Bridge - Chrome Web Store
Instantly find and follow the same users from your Twitter follows on Bluesky.
chromewebstore.google.com
Anyone who is anti-vax is pro-death. Period. The science and data do not lie. And they don’t care about your podcast.
Skeetorial time! We need to chat about pharmacokinetics & pubs. If you plan to publish in vivo PD/efficacy studies, the minimum credible accompanying PK package is an IV leg + an IP/PO leg if that's your eventual route. In the same species, preferably at the planned efficacy dose. 1/
a close up of a hamster 's face and paws
ALT: a close up of a hamster 's face and paws
media.tenor.com