Register for #HumanImmuno26: Genes & Environment! 🗓️ 13-15 May 2026 Join researchers in #immunology, genetics, functional genomics, and physiology to exchange knowledge and explore solutions to key gaps in understanding human immune diversity. 📎 bit.ly/4rpfwpW #ImmunoGenetics #ImmunoSky 🧪💉

🚨New Paper in Cell 🧵🔎 Happy to share our work led by the @camilahcoelho.bsky.social, on mAbs against mpox. We were very excited (and lucky!) to contribute to this collab. effort. 🦠“Human monoclonal antibodies targeting A35 protect from death caused by mpox”🦠 doi.org/10.1016/j.cell.2025.08.004

🚨 New Publication!!! I’m thrilled to share our latest study, “Clonotype-Enriched Somatic Hypermutations Drive Affinity Maturation of a Public Human Antibody Targeting an Occluded Sarbecovirus Epitope”. www.cell.com/cell-reports... [1/4]

Clonotype-enriched somatic hypermutations drive affinity maturation of a public human antibody targeting an occluded sarbecovirus epitope

Rao et al. demonstrate that convergent somatic hypermutations in the light chain, enriched within a sarbecovirus-specific public antibody clonotype, drive affinity maturation. This antibody targets a ...

cell.com

🧵 New collaborative study just published in Nature Biomedical Engineering: “A modular vaccine platform for optimized lipid nanoparticle mRNA immunogenicity” doi.org/10.1038/s41551-025-01478-6

A modular vaccine platform for optimized lipid nanoparticle mRNA immunogenicity - Nature Biomedical Engineering

A modular platform for engineering immunogenic lipid nanoparticle mRNA vaccines is used to display antigens from a variety of pathogens to induce antigen responses.

doi.org

Check our important piece below 👇! "We urge authors, reviewers, and editors to revise the default use of MSM as an epidemiological label. Our intention is not to dismiss important epidemiological context but to prevent the stigmatization of affected populations." @thelancetinfdis.bsky.social

A call to move beyond MSM-centric framing in mpox research

The resurgence of mpox poses urgent public health challenges, and the scientific community has mobilised admirably to understand its transmission, immunity, and therapeutics.1,2 However, the language ...

thelancet.com

Carolina Lucas@carolilucas.bsky.social · last yr.

Words matter. Scientific language shapes public perception and policy. Framing mpox as a disease of GBMSM may have reflected early patterns, but continuing this narrative misrepresents transmission risks and reinforces stigma. With Camila Coelho, Vries & Zucker 🌈 www.thelancet.com/journals/lan...

Words matter. Scientific language shapes public perception and policy. Framing mpox as a disease of GBMSM may have reflected early patterns, but continuing this narrative misrepresents transmission risks and reinforces stigma. With Camila Coelho, Vries & Zucker 🌈 www.thelancet.com/journals/lan...

A call to move beyond MSM-centric framing in mpox research

The resurgence of mpox poses urgent public health challenges, and the scientific community has mobilised admirably to understand its transmission, immunity, and therapeutics.1,2 However, the language ...

thelancet.com

Day 3: Carolina Lucas (Yale) @carolilucas.bsky.social‬ discussing with students and postdocs how her research in immunity to viruses (especially emerging pathogens) shifted from mouse to human systems & the surprises along the way. #Immunology www.ccii.med.kyoto-u.ac.jp/en/events/

Center for Cancer Immunotherapy and Immunobiology@ccii-kyoto.bsky.social · last yr.

Day 2. Gabriel Victora @victora.bsky.social discussing with students and postdocs the long & winding road to developing LIPSTIC, the tool his lab created to track cell-cell interactions in vivo www.nature.com/articles/s41...

Our April issue is now online: www.thelancet.com/journals/lan... Our journal is #OpenAccess, so you are free to explore all of our content. But these hashtags offer a flavour: #SARS-CoV-2 #COVID-19 #chikungunya #Neisseria #CHIM #mpox #BSI #Ecoli #Klebsiella #Mycoplasma #IDSky #ClinMicro #OA

New research article The impact of #orthopoxvirus vaccination and #Mpox infection on cross-protective immunity: a multicohort observational study www.thelancet.com/journals/lan... #IDSky #ViroSky #ClinMicro #OpenAccess #OA

🚨 Our new study is live in The Lancet Microbe! “The impact of orthopoxvirus vaccination and Mpox infection on cross-protective immunity: a multicohort observational study” Led by @jaycrandell.bsky.social , Valter Monteiro and Lauren Pischel www.sciencedirect.com/science/arti... A thread 🧵!

The impact of orthopoxvirus vaccination and Mpox infection on cross-protective immunity: a multicohort observational study

Cross-reactive immune memory responses to orthopoxviruses in humans remain poorly characterised despite their relevance for vaccine design and outbrea…

sciencedirect.com

Who funds biomedical research? @nature.com www.nature.com/articles/d41...

“Americans who value the spirit of discovery — and eagerly await new ways to confront disease, strengthen our economy and improve the quality of human life — need to issue a strong outcry… This is not a fight that our country can afford to lose.” Indeed www.nytimes.com/2025/02/14/o...

Opinion | American Science is Under Attack

The Trump administration hobbles research and endangers the public health.

nytimes.com

Use this form to tell us how the new US administration is affecting your research, or suggest future coverage https://go.nature.com/4aYn9Me

Are the Trump team’s actions affecting your research? How to contact Nature

Use this form to share information with Nature’s news team, or to make suggestions for future coverage.

go.nature.com

The set up: "This extensive use of antibiotics is based on the assumption that, other than toxicity issues when used in large doses, antibiotics disrupt biological processes in microbes and not the host." www.science.org/doi/10.1126/...

Antibiotics damage the colonic mucus barrier in a microbiota-independent manner

Antibiotics inhibit production of the protective mucus in the colon, thus predisposing to gut inflammation.

science.org

For those wondering why we seem to be so behind when it comes to effective mucosal vaccines against respiratory viruses, this really excellent overview from leaders in the field offers a great summary: www.nature.com/articles/s41... few additional points for those who want a bit more detail🧵:

Challenges for developing broad-based mucosal vaccines for respiratory viruses - Nature Biotechnology

Nature Biotechnology - Challenges for developing broad-based mucosal vaccines for respiratory viruses

nature.com

So we haven’t seen this occur in nature and there are other hurdles H5N1 would have to surmount to efficiently spread human to human. www.science.org/doi/10.1126/...

A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors

In 2024, several human infections with highly pathogenic clade 2.3.4.4b bovine influenza H5N1 viruses in the United States raised concerns about their capability for bovine-to-human or even human-to-h...

science.org

ICYMI: Analysis of blood serum found #LongCOVID was characterized by altered levels of certain immune complement proteins. These changes linked to complement activation and signs of dysregulation of the coagulation system. #Immunosky www.science.org/doi/10.1126/...

Persistent complement dysregulation with signs of thromboinflammation in active Long Covid

Analysis of blood revealed that Long COVID is characterized by changes to complement proteins and platelet activation.

science.org

Fascinating new paper about how commensal #fungi can promote #type2 responses in mice, a process involving fungal induction of #IL-33 🍄 🧪 #ImmunoSky www.nature.com/articles/s41...

Fungal symbiont transmitted by free-living mice promotes type 2 immunity - Nature

Kazachstania pintolopesii is a highly prevalent fungal symbiont that can trigger type 2 immunity and influence the composition of the gut mycobiome, as well as immune and disease phenotypes.

nature.com

✨ Ever wondered why B cells are so fond of IL-2? Wonder no more! Our study is now published in Immunity @cellpress.bsky.social 🔍📑 A truly perfect Thanksgiving gift! 🧑‍🔬💉🔬https://authors.elsevier.com/c/1kAq43qNrUxuTR

The danger theory of immunity strikes back... rdcu.be/d1uQN

The measles vaccine is given as a shot but it is surprisingly good at inducing protective immunity in the respiratory tract (mucosal IgA). Our new study provides some clues about why...a thread (1/8) #IDSky #MedSky #lungs #immunology #ImmunoSky academic.oup.com/jid/advance-...

Can colleagues amplify this appeal to journals and journal editors to open accounts on Bluesky, please? @MicrobioSoc @TrendsMicrobiol @CellCellPress @JBacteriology @jbiolchem @Nature @ScienceMagazine @PNASNews @MolMicroEditors @NAR_Open @NatureMicrobiol @NatureComms @ASMicrobiology 🙏 🦠🧪🧫🧬

🧪Today, our lab group decided to take a break from scientific experiments and embrace tranquility with some llama yoga! Lhamaste🦙🧘‍♂️

The COVID-19 pandemic is now more challenging due to the Omicron variants. Robust public health measures, research and global cooperation are critical in addressing this crisis. Our recent @ScienceTM study is particularly important for countries relying on CoronaVac vaccines👇👇

In case you were wondering how a lab with Brazilians looks like during the World Cup 🏆…

Our newest study is out! We report an age-dependent impairment in antibody responses elicited by homologous, but not heterologous CoronaVac booster dose during the Omicron wave. https://www.medrxiv.org/content/10.1101/2022.10.04.22280704v1 Special thanks to @mab_sp125 @ValterVSM and...

Today Brazilians are faced with a simple choice: democracy or fascism. Today we vote for a new beginning. We vote for public education, public health, to science, against environmental destruction and poverty. #LULA2023 #ForaBolsonaro

First day as assist. prof. at @YaleIBIO after incredible years with @VirusesImmunity! My lab will focus on emerging viruses. The bio has changed but I haven’t. Incredibly honored for this opportunity and grateful to mentors, family, friends that encouraged me to make today happen

Nosso artigo descrevendo a imunogenicidade do regime de vacinacao heteróloga (2 doses de CoronaVac seguidos pela dose de reforco com Pfizer foi publicado hoje: https://www.nature.com/articles/s41591-022-01705-6 Algumas atualizações em relação ao preprint 🧵..

Nosso preprint descreve a imunogenicidade do regime de vacinacao heterologa: 2 doses de CoronaVac seguidos pela dose de reforco com Pfizer 🧵. (verso em português 🇧🇷) https://www.medrxiv.org/content/early/2021/12/29/2021.12.27.21268459