On #WorldHepatitisDay: Hepatitis E Virus causes 20 M infections/3.3 M symptomatic cases annually. A hepatitis E vaccine was 95.5% effective in a 2007 trial, yet was never developed further. Why? www.nejm.org/doi/full/10.... @worldhepalliance.bsky.social #idsky #episky #medsky #publichealth
Catherine Berry (she/her)
@catherineberry.bsky.social
ID MD, currently working on stewardship programming. Currently upskilling in NTM. Previously TB-Practecal and endTB with MSF. #IDsky #TBsky #AMSsky
The bug I fear most when ICU wake me up at night. Totally deserves status as a true superbug @joshosowicki.bsky.social - great to hear you on Breakpoints @sidpharm.bsky.social ... breakpoints-sidp.org
Breakpoints: The SIDP Podcast – A Free Educational Podcast
Breakpoints: The SIDP Podcast provides a free educational podcast to discuss current literature and share information about infectious diseases.
breakpoints-sidp.org
Also shouldn't be completely out shadowed by the Ben pen domain. www.thelancet.com/journals/lan... @gurujosh.bsky.social
Benzylpenicillin versus flucloxacillin or cloxacillin for the treatment of penicillin-susceptible Staphylococcus aureus bacteraemia (SNAP): an international, multicentre, open-label, non-inferiority r...
Although the prespecified non-inferiority criterion for benzylpenicillin was not met, the probability of benzylpenicillin being non-inferior for mortality, along with a reduction in risk of AKI, indic...
thelancet.com
Well, it only took ‘em 2 years to get past Reviewer 2, but they did it & as we say in Scotland, ‘it’s Oot’! SNAP paper 1, available now. Congrats 2 Todd Lee, Steve Tong, Josh Davis & the rest. First dram of this bottle is in your honour! Slàinte!! #IDsky #SNAP #morelikePoocloxacillin
Well, it only took ‘em 2 years to get past Reviewer 2, but they did it & as we say in Scotland, ‘it’s Oot’! SNAP paper 1, available now. Congrats 2 Todd Lee, Steve Tong, Josh Davis & the rest. First dram of this bottle is in your honour! Slàinte!! #IDsky #SNAP #morelikePoocloxacillin
🔥Just published 🔥NEJM SNAP RCT In patients with MSSA bacteremia, cefazolin was noninferior to flucloxacillin or cloxacillin with respect to 90-day mortality and was associated with a lower incidence of acute kidney injury. #idsky www.nejm.org/doi/full/10....
My cartoon in the January 22, 2026 issue of The New Yorker
Thanks to high #vaccination rates, the Northern Territory of #Australia had not seen locally acquired #diphtheria disease since the late 1990s - until cutaneous cases emerged in 2025 and respiratory cases in 2026 Read about the #outbreak ➡️ bit.ly/EUS3123 #IDSky #EpiSky #MicroSky #MedSky 🧪🛟 #HIVSky
Findings: Use of antibiotics is unlikely to improve patient-important outcomes in individuals with non-severe, severe, or critical COVID-19 infections. The 2025 WHO guidelines recommend against antibiotics in patients with low suspicion of bacterial infection #AMR #IDSky #MedSky
New research article Effects of antibiotic treatment on clinical outcomes in patients with #COVID-19: a systematic review and meta-analysis www.thelancet.com/journals/lan... #IDSky #ClinMicro #ViroSky #AMR #OpenAccess #OA
I'm informed that the police were called. To a medical conference. Because the editors of a journal held views. Sorry?
Tuberculous Meningitis (TBM) is an often lethal form of tuberculosis with damage to the brain ,the treatment regimen for TBM comprises 4 antitubercular drugs and anti-inflammatory glucocorticoids. The regimen has not changed for over 40 years #idsky
🆕💥🔴Review summarizes recent clinical trials for treatment of tuberculous meningitis 🔺Disappointing result:high dose Rifampin HARVEST 🔺The only adj Rx supported is dexamethasone(may not be universal: HIV+, ACT HIV, no survival benefit) 🔺Several ongoing RCTs #idsky www.tandfonline.com/doi/full/10....
"In this proof-of-concept study, 4 months of delamanid, bedaquiline, and quabodepistat showed a promising end-of-treatment non-inferiority signal versus 6 months of RHEZ and was generally well tolerated." @thelancetinfdis.bsky.social #IDSky #TBSky www.thelancet.com/journals/lan...
Efficacy and safety of a 4-month quabodepistat, delamanid, and bedaquiline regimen for drug-susceptible pulmonary tuberculosis: a multicentre, open-label, randomised, proof-of-concept, non-inferiority...
In this proof-of-concept study, 4 months of DBQ showed a promising end-of-treatment non-inferiority signal versus 6 months of RHEZ and was generally well tolerated. Our results support further studies...
thelancet.com
Amazing 😍 🔥SHORTEN 2 RCT A 7-day treatment course is superior to 14 days for uncomplicated Pseudomonas aeruginosa bacteremia, achieving similar clinical response rates with lower antibiotic exposure, fewer superinfections, and fewer serious adverse events #idsky @shorten2trial.bsky.social
I'm giving year 5 medical students a talk on the pharmacology of antimicrobials. Delivery via zoom. 2 hours 🙄. Tips for keeping it interesting? What pearls do you always include?
Mr. Incredible Working Tiredly
ALT: Mr. Incredible Working Tiredly
static.klipy.com
WHO declares Ebola outbreak in DRC and Uganda an international public health emergency… www.who.int/news/item/17... #IDSky
Epidemic of Ebola Disease caused by Bundibugyo virus in the Democratic Republic of the Congo and Uganda determined a public health emergency of international concern
Pursuant to paragraph 2 of Article 12 - Determination of a public health emergency of international concern, including a pandemic emergency of the International Health Regulations (2005) (IHR), the Di...
who.int
Listening to the talkative teens currently inhabiting my living room. Can confirm that they have an utter disdain for AI, and by extension, for teachers who use AI. Also, that they discuss AI and its associated issues with far more knowledge and sophistication than most adults. #TheKidsAreAlright
The Exultant trial showed an expanded tuberculosis diagnostic approach did not improve proportion of HIV positive patients started on tb treatment by 72 hours or improve mortality. What does it tell us? www.sciencedirect.com/science/arti...
Expanding Xpert MTB/RIF Ultra and lateral flow urine lipoarabinomannan testing for diagnosis of tuberculosis among adults living with HIV admitted to hospitals in Tanzania and Mozambique (EXULTANT): a...
Tuberculosis is the main cause of death among hospitalised people living with HIV. Non-sputum-based diagnostics could improve patient outcomes. The EX…
sciencedirect.com
3 Dead of Suspected Hantavirus Infections on Cruise Ship, W.H.O. Says Whoa. This is crazy. #IDsky #epidemiology #virology #travel
3 Dead of Suspected Hantavirus Infections on Cruise Ship, W.H.O. Says
nytimes.com
Now this looks like an ep for thee About a drug that gets into your pee It’s known to treat crypto and also yeast It’s time to learn about flucytosine podcasts.apple.com/gb/podcast/i... #idsky #microsky #podcast
137. Flucytosine
Podcast Episode · ID:IOTS - Infectious Disease Insight Of Two Specialists · 27 April · 22min
podcasts.apple.com
I'm pretty convinced by the recent Bayesian meta-analysis of selective decontamination of the digestive tract for ventilated patients. evidence.nejm.org/doi/10.1056/... I have to admit that I instinctively *really* don't like this as an idea (but hey - I guess that's what RCT evidence is for) #IDSky
Selective Decontamination of the Digestive Tract in Adult Mechanically Ventilated Patients — An Updated Systematic Review with Bayesian Meta-Analysis
There is uncertainty whether the use of selective decontamination of the digestive tract (SDD) as a preventive antimicrobial strategy reduces mortality in adult patients receiving mechanical ventil...
evidence.nejm.org
At #ESCMID2026 Trial Run session, Dr. David. Paterson made a call to the ID community to join platform trials. So I want to tell you how we did that. I am a clinician, and also medical lead for IPC and stewardship. Our small but mighty ASP was already reviewing all pts with bacteremia 1/ #IDSky
Glad to see older Australians included on the schedule for rsv. Would be great to see the epidemiology change as for other infections and hospital impact reduce for coming seasons. www.racgp.org.au/gp-news/medi...
RACGP - RACGP welcomes inclusion of RSV vaccine in National Immunisation Program for older Australians
RACGP Media releases
racgp.org.au
Our April TBPod episode is live! Dr Padmasayee Papineni joins Dr Jack Callum to explore tuberculosis care through narrative medicine, compassion, and lived experience. Listen here: www.buzzsprout.com/851944/episo... #TBPod #Tuberculosis #NarrativeMedicine
The People Behind the Numbers: Dr Padmasayee Papineni on TB Care, Stigma & Social Support - The TBPod
Dr Padmasayee Papineni, Consultant and Co‑Clinical Director in Infectious Diseases at London North West University Healthcare NHS Trust, joins Dr Jack Callum to discuss the lived experience of tubercu...
buzzsprout.com
DETECT (@advance-id.bsky.social, Singapore) is conducting a global survey to assess gaps in clinical microbiology diagnostics. If you’re a lab manager, senior lab staff, ID physician, or expert in your facility’s diagnostic workflows, the team wants to hear from you! #IDSky 🧪 🔗 bit.ly/4dxdDDs
When they say “what’s the harm in one more day of antibiotics?”
✈️🌍 Wanna lead Social Science research with #MSF and travel the world while helping others? Apply and join us! msf.lu/en/conseille... #medsky #idsky #episky #humanitarian @msf.ca @msfluxor.bsky.social
msf.lu
New research article #Bedaquiline resistance in patients with Xpert MTB/RIF Ultra-tested #rifampicin resistant #tuberculosis in the Western Cape, South Africa: a prospective study www.thelancet.com/journals/lan... #IDSky #ClinMicro #TBSky #TB #AMR #OpenAccess #OA
Everything is a zoonosis! Drawing/listing challenge. #29 - Iguana Requested by @catherineberry.bsky.social and inspired by @iuidfellowship.bsky.social Found an interesting report of Burkholderia pseudommallei abscess in a pet iguana, could that have zoonotic potential? #IDSky #VetSky