Excited to be attending and presenting my work developing novel optogenetic tools at BMES 2026!!!
Caitlin Donahue
@cetd0101.bsky.social
Postdoc in UDS. PhD from White Lab from University of Notre Dame. Biochemistry B.S. from Roanoke College. Opinions are my own
Excited to share Will Anderson's publication describing his optogenetic FGF/ERK activator transgenic #zebrafish! Will demonstrated spatially localized FGF/ERK activation with 1 min light exposure at 1 dpf 👀 journals.biologists.com/bio/article/...
Zach wrapped up his summer internship with a poster presentation!!
Excited to be attending and presenting my work at the 2026 FASEB Dynamics and Encoding in Cell Signaling meeting!!
So excited to be able to mentor Zach this summer in the lab!!! He will be working with me to develop a new optogenetic tool for use in zebrafish! 🔬 @katwrog.bsky.social
Congrats to the 2026 SDB Award Winners! Conklin Medal: Lee Niswander SDB Lifetime Achievement Award: Alexandra Joyner Hamburger Outstanding Educator Prize: Roberto Mayor Hay New Investigator Award: Jeffrey Farrell SDB Trainee SciComm Award: Nicholas Desnoyer bit.ly/4afnjiC
Ok, friends! If you’re a Daniocell user, it’s now available again outside of the NIH. Very sorry for any inconvenience this posed for any of you and thanks for your patience. We’re taking additional steps to hopefully prevent similar outages in the future. Happy surfing 🎣
If you love Daniocell, but wish it could generate analyses specific to YOUR genes & cell types of interest, check out DaniocellDesktop - a new point-and-click app for Mac and Windows that enables reanalysis of the Daniocell data without programming: daniocell.nichd.nih.gov/desktop/ (1/4)
Honored that I was able to attend a seminar by Dr. Carolyn Bertozzi yesterday! I was absolutely inspired by both her science and career journey. 🧪 🥼
Grateful to have received a NICHD Career Development Award to create new optogenetic tools to manipulate signaling in zebrafish. Thanks to UDS (@katwrog.bsky.social) for supporting this project!!
Excited to be part of this story characterizing optogenetic tools!!
Happy to share a new preprint from my lab! We characterize the on/off kinetics, light dosage-dependence, and more for a suite of optogenetic signaling activators in zebrafish embryos 💡 www.biorxiv.org/content/10.1...
An advanced toolset to manipulate and monitor subcellular phosphatidylinositol 3,5-bisphosphate. New study from Joshua Pemberton, John Burke, Tamas Balla (National Institute of Child Health and Human Development) and colleagues: rupress.org/jcb/article/... #Biochemistry #CellSignaling #lipid
🎉 Excited to share our new work: “Adhesion-driven tissue rigidification triggers epithelial cell polarity”, now on @biorxivpreprint.bsky.social ! A huge thank you to @nicolettapetridou.bsky.social, Bernat, @crisp-c.bsky.social, Adrián, and everyone involved! 🙌 🧵⤵️
Intracellular pH dynamics respond to microenvironment stiffening and mediate vasculogenic mimicry through β-catenin https://www.biorxiv.org/content/10.1101/2024.06.04.597454v1
Intracellular pH dynamics respond to microenvironment stiffening and mediate vasculogenic mimicry through β-catenin https://www.biorxiv.org/content/10.1101/2024.06.04.597454v1
Dysregulated intracellular pH (pHi) dynamics and an altered tumor microenvironment have emerged as d
biorxiv.org
Intracellular pH regulates β-catenin with low pH increasing adhesion and signaling functions https://www.biorxiv.org/content/10.1101/2024.03.22.586349v1
Intracellular pH regulates β-catenin with low pH increasing adhesion and signaling functions https://www.biorxiv.org/content/10.1101/2024.03.22.586349v1
Intracellular pH (pHi) dynamics are linked to cell processes including differentiation. The adherens
biorxiv.org
Trenton does really interesting work!! Follow him and check out his research.
Hi Folks, I’m Trenton W. Ford, a Data Science Professor at William and Mary where I direct a research lab on Agentic AI, social media, and misinformation. I don’t know how the algorithm works on Bluesky, but I’d like my feed to be full of scientists, gamers, hikers, and stationary obsessed people!
Leading Edge is celebrating a milestone: 100 (actually 102!) new assistant professors!!! 🎉🥳🎊 Learn more about them: www.leadingedgesymposium.org/fellows/ Applications are now open for the 2025 Leading Edge cohort! (Deadline Feb 3). You do NOT need to be ready for the job market to apply.
Several from the #zebrafish community have joined Leading Edge Fellows 👩🔬 Highly recommend submitting an application, if you’re keen!
Leading Edge is celebrating a milestone: 100 (actually 102!) new assistant professors!!! 🎉🥳🎊 Learn more about them: www.leadingedgesymposium.org/fellows/ Applications are now open for the 2025 Leading Edge cohort! (Deadline Feb 3). You do NOT need to be ready for the job market to apply.
A matter of threshold - www.biorxiv.org/content/10.1...
Optogenetic control of a GEF of RhoA uncovers a signaling switch from retraction to protrusion
The ability of a single protein to trigger different functions is an assumed key feature of cell signaling, yet there are very few examples demonstrating it. Here, using an optogenetic tool to control...
biorxiv.org
New UDS Writing Club post by postbac Matt Monaghan! Diving into the @schierlab.bsky.social's exciting preprint using weMERFISH to create 3D spatial atlases of #zebrafish gene expression & chromatin accessibility kwrogers-lab.org/uds-writing-...
Quantitative Imaging From Acquisition to Analysis applications are due Jan 31! 2 weeks of total microscopy & image analysis immersion with me, @talleylambert.bsky.social, @bethcimini.bsky.social, @florianjug.bsky.social & Hunter Elliott! See comments... (1/5) meetings.cshl.edu/courses.aspx...
Quantitative Imaging: From Acquisition to Analysis
Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.
meetings.cshl.edu
I am happy to announce I have joined the UDS as a postdoctoral researcher!! I’m excited to work with this amazing group of scientists! 🔬