these dumb mfs have one note, the team that just beat australia is full of Black players and immigrants lmao please shut the fuck up
Will Bunch@willbunch.bsky.social · 2mo agoFascists are not welcome at this party. Get lost
Charis Ramsing
@charisramsing.bsky.social
PhD Candidate at UC Davis. Big fan of plant-microbe interactions, nature, and a littttleee too into women’s soccer. (she/her/hers)
Will Bunch@willbunch.bsky.social · 2mo ago
When people think the USMNT might be as good as the ladies after one exciting half of footy:
The U.S. government requires visa applicants to make all of their social media accounts fully public or risk being denied entry. This is straight out of 1984. Your right to privacy doesn’t just disappear at the border for millions of people, it disappears before they ever set foot here.
Excited to share our new preprint! We explore how experimental context influences immune responses triggered by elf18 and flg22 in Arabidopsis. Huge thanks to @gittacoaker.bsky.social for her guidance and support, and to Hanxu Sha for her help on this project. www.biorxiv.org/content/10.6...
Experimental Context Shapes PRR-Mediated Immune Output Sensitivity in Arabidopsis
Pattern recognition receptors (PRRs) mediate plant immune responses by detecting extracellular immunogenic patterns, including microbe-associated molecular patterns (MAMPs). PRR signaling is commonly assessed using assays such as reactive oxygen species (ROS) bursts, cytosolic calcium influx, mitogen-activated protein kinase (MAPK) activation, and seedling growth inhibition (SGI), which are performed in distinct experimental systems, including seedlings grown on artificial media and soil-grown rosettes. Here, we systematically compare receptor kinase immune outputs triggered by the bacterial MAMPs elf18 and flg22 in Arabidopsis thaliana seedlings and rosettes across a range of concentrations. Rosettes exhibited greater sensitivity than seedlings in ROS assays, whereas cytosolic calcium responses measured using the Aeqcyt/pMAQ2 reporter were stronger in seedlings, correlating with reduced reporter transcript accumulation in rosette tissue. MAPK activation was consistently stronger in rosettes, whereas SGI assays revealed higher sensitivity to elf18 than flg22 in seedlings despite flg22 inducing stronger early signaling outputs. Together, these results demonstrate that canonical PRR-mediated immune outputs are differentially sensitive to experimental context and should not be interpreted as interchangeable measures of immune activation. These findings highlight the importance of considering experimental conditions when comparing immune responses across assays and developmental stages. ### Competing Interest Statement The authors have declared no competing interest. National Institutes of Health, https://ror.org/01cwqze88, R35GM136402 Fundación Alfonso Martín Escudero, https://ror.org/02897ye82
biorxiv.org
About last night’s scrambling from gun fire at White House reporters dinner .. Rep Jamie Raskin (D-MD) makes a critical point on CNN: “This is happening in schools across the country.. the kids have no resources to process their trauma”
I really do not know how to put into words how absolutely idiotic and terrible this would be.
Sam Bagenstos@sbagen.bsky.social · 4mo agoThis administration is just hell-bent against generating knowledge about the world. www.notus.org/health-scien...
Joining the Coaker lab is one of the best decisions I’ve ever made. Come join us (but only if you like fun and love a good lab environment) !!
Gitta Coaker@gittacoaker.bsky.social · 4mo agoWe are hiring! We’re excited to recruit a postdoc to our lab at UC Davis to work on plant immune engineering and single-cell analyses of plant pathogen interactions. Apply by June 1. Please repost. www.coakerlab.org/postdoctoral...
I'm one of those trans women. I worked ground ops for Artemis I. I am torn between celebrating the success of my friends and peers and grieving how my dream of working for NASA was shattered by hateful assholes in Tallahassee
Takaichi’s Castle@discographette.online · 4mo agocongratulations to the astronauts who get credit for a moon mission using rocket development work by trans women who had to quit their job and flee the state of florida and can’t celebrate this win with their coworkers
What I think many Americans don't quite grasp is how quickly the Iran conflict could spiral into a humanitarian crisis for many parts of the world. @newhumanitarian.bsky.social www.thenewhumanitarian.org/photo-featur...
Iran war pushes Philippines fishing communities to the brink
Fuel prices have risen by almost 100%, forcing many families who can no longer turn a profit to borrow food or skip meals altogether.
thenewhumanitarian.org
yeah im bummed about sora. bummed i sora bunch of stupid fake videos
inaugural game red for Boston feels about right
Getting shown up in the arena of elite impunity by *the British monarchy* is an incredible “America at 250!” achievement
I am. But there are three things at play here regarding ICE collecting private data. Quick rundown on the issue, why you should be paying attention, and what I'm doing about it:
Tressie McMillan Cottom@tressiemcphd.bsky.social · 7mo agoSo which politician is calling for the dismantling of the probably illegal database that ice & this government is collecting biometric data of protesters?
ICE in Minnesota: They tear gas protestors detained on the ground. They murdered Renee Good They kidnapped a 5 year old and used him as bait; kidnapped 2 year old They beat and murdered a VA nurse Then ICE leaders went on TV and lied about it Ultimate gaslighting
Former Special Counsel Jack Smith: "I stand by my decisions as special counsel, including the decision to bring charges against President Trump. Our investigation developed proof beyond reasonable doubt that President Trump engaged in criminal activity... No one should be above the law".
Party upset with Real ID Act over privacy concerns and because it would lead to a national ID card warns citizenry to be prepared to identify themselves via national ID card.
the only thing that could make me feel better right now is finding out Aaron Rodgers’ wifi is an AI bot 🤞
And we're bombing innocent people (again).
@charisramsing.bsky.social gave a great seminar on Clavibacter for UC Davis’ Plant Pathology Department today. New insights into tomato colonization and effector recognition. #MPMI
The NWSL has 99 problems, but a trans player ain’t one. www.theguardian.com/football/202...
Women’s soccer faces plenty of serious threats. So why the panic about trans players? | Lesley Ryder
Angel City’s Elizabeth Eddy was rebuked by her own teammates for an op-ed on trans players. It’s easy to understand their objections
theguardian.com
We firmly believe firing comedians is not a sign of a healthy democracy. In some countries, they even elect them to defend against ambitious fascists. — PM Tuxley II
I’m honored to share the illustration accompanying our receptor engineering paper in Nature Plants. Created by the talented Phoebe Sinner from the Coaker lab, this artwork elegantly highlights how natural diversity contributes to differences in receptor specificity. www.nature.com/articles/s41...
Washington DC has 702,000 people, is 45% Black and has 0 senators Wyoming has 590,000 people, is 86% white and has 2 senators DC needs a state with proper representation, not a military takeover
Missing my fellow Coakerites today! I tried to recreate my favorite MPMI 2023 photo but this time it’s just me 😢. Another reminder of the impact politics has on science and that many incredible academics working in the US aren’t here this year. #2025ISMPMI
