Christin Herrmann

@christinviral.bsky.social

Scientist with Victor Torres in the Department of Host Microbe Interactions at St. Jude. Postdoc in the Cadwell Lab (NYU and UPenn) and grad school in the Weitzman Lab (UPenn).

Excited to share this collaborative study with @ritatamayo.bsky.social showing that E. faecalis influences C. diff morphology through the phase variable CmrRST system! This work was co-led by the amazing team of @ashleyweiss.bsky.social and Jilarie Santos-Santiago!

bioRxiv Microbiology@biorxiv-microbiol.bsky.social · last yr.

Enterococcus faecalis modulates phase variation in Clostridioides difficile https://www.biorxiv.org/content/10.1101/2025.07.24.666506v1

Incredibly honored to be selected as a @bwfund.bsky.social Investigator in the Pathogenesis of Infectious Disease. Thank you to @bwfund.bsky.social for supporting our work - I am thrilled to join this amazing community! And special thank you to my AMAZING team (past & present) for getting us here!

Burroughs Wellcome Fund@bwfund.bsky.social · last yr.

Announcing the 2025 Investigators in the Pathogenesis of Infectious Disease www.bwfund.org/news/announc... #bwfpath

1/3 It’s official 🙌🏽 The Reyes Ruiz Lab is opening in 2026 at the University of Wisconsin, Madison in the Department of Pathobiological Sciences. My lab will focus on host antibacterial effectors and adaptation of bacteria to host-imposed stress during S. aureus infections.

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Proud of this work, led by the amazing Jeannette Tenthorey (now Assistant Professor at UCSF), demonstrating the adaptive power of single indel mutations in host-virus arms races, but a little sad that this is the coda to her amazing postdoc in the Malik & Emerman labs. www.cell.com/cell-genomic...

Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations

Tenthorey et al. compare the effects of missense and indel mutations on the acquisition of functional novelty by the rapidly evolving antiviral protein TRIM5α. They find that single indel mutations al...

cell.com

Congratulations Ying-Han Chen and Kim Zaldana for showing how B cells are altered when lab mice 🐭 are released outdoors! www.science.org/doi/10.1126/... Here’s some context for the paper followed by how gov’t 💰 + other sources combine to make these types of studies possible 1/n

Rewilding catalyzes maturation of the humoral immune system

Releasing laboratory mice into the natural environment enhanced maturation and activation of the humoral immune system.

science.org

In the US alone, each year, norovirus causes ~20 million acute gastroenteritis cases, 70,000 hospitalizations, up to 800 deaths, at a cost of ~$10.6 billion annually. An pill vaccine shows considerable promise in a clinical trial, establishing mucosal immunity www.science.org/doi/10.1126/...

An oral norovirus vaccine tablet was safe and elicited mucosal immunity in older adults in a phase 1b clinical trial

An oral norovirus vaccine tablet is safe and induces strong mucosal and systemic immune responses in adults aged 55 to 80 years.

science.org

Once upon a time, some villagers came across a large, ornate wooden box in the local woods. On the side of the box was a message: “Whatever money you put in this box will, in future, grow to become 2.5 times larger.” 1/

Excited to share our latest preprint! We find that DCs undergo heterogeneous cell death- either pyroptosis or apoptosis upon bacterial blockade of host translation- to restrict Legionella infection. Congrats to my PhD student @vvazquez.bsky.social & co-authors! Check out his bluetorial 🧵 below! 👇

Víctor R. Vázquez Marrero, PhD@vvazquez.bsky.social · 2y ago

Bluesky post I’m very excited to share a preprint of the bulk of my thesis work in @sunnyshinlab.bsky.social where we investigate how dendritic cells respond to Legionella pneumophila www.biorxiv.org/content/10.1...