Claudia Jakubzick (Dartmouth) gave a lecture on “Myeloid Cells in Immune Responses.” She described how macrophage gene expression & function vary by the tissue in which they reside, & how monocytes influence diverse immune processes such as inflammation and immunotherapy. 🔗 learning.aai.org
Research briefing for our new tumor-associated macrophage paper 👇 www.nature.com/articles/s41... rdcu.be/faeRM
Yin and yang of tumor-associated macrophages
Nature Immunology - Our work reveals functional heterogeneity among interstitial macrophages, showing that distinct chemokine programs determine immune cell positioning and interactions within lung...
rdcu.be
$2.45 billion NIH grant cuts and ~2300 terminated active research grants were DOGE'd in early 2025 Who were most affected? www.pnas.org/doi/full/10.... Early career and women researchers
Macrophage lineage and spatial compartmentalization govern tumor immunity @natimmunol.nature.com @claudjak.bsky.social @xinli0419.bsky.social www.nature.com/articles/s41...
Excited to share our work @springernature.com Building on our work defining TRMacs heterogeneity, we show that distinct chemokine+ IM subsets and recruited TAM niches shape pro- and anti-tumor immunity within to the TME, while Ag+ moDCs trafficking to LNs dampen DC-based neoAg vaccine rdcu.be/e9uZu
Chemokine-defined macrophage niches establish spatial organization of tumor immunity
Nature Immunology - Jakubzick and colleagues show that the tumor microenvironment is shaped by opposing programs in tissue-resident CD206hi and CD206lo interstitial macrophages and Ly6c2+Fn1+Vcan+...
rdcu.be
Tor D. Wager (@torwager.bsky.social) of Dartmouth College is the recipient of a 2026 Atkinson Prize in Psychological and Cognitive Sciences! He is being honored for pioneering research revealing how the brain shapes pain, emotion, and belief. Read more: www.nasonline.org/award/atkins... #NASaward
Claudia Jakubzick opened Day 2 of the AAI Advanced Course in Immunology with a lecture on “Myeloid Cells in Immune Responses.” Describing how macrophage gene expression and function vary by the tissue in which they reside, and how monocytes influence diverse immune processes.
Check out our new preprint www.researchsquare.com/article/rs-6...
The Dichotomy of Tumor Control by Recruited and Resident Tumor-Associated Macrophages
Tumor-associated macrophages (TAMs) play dual roles in cancer, either promoting or suppressing tumor progression, complicating therapeutic approaches. TAMs include recruited macrophages (recMacs), der...
researchsquare.com
check out our new preprint www.researchsquare.com/article/rs-6...
The Dichotomy of Tumor Control by Recruited and Resident Tumor-Associated Macrophages
Tumor-associated macrophages (TAMs) play dual roles in cancer, either promoting or suppressing tumor progression, complicating therapeutic approaches. TAMs include recruited macrophages (recMacs), der...
researchsquare.com
Special shout out to recent grad Dr. Xin Li (@xinli0419.bsky.social) from the Jakubzick (@claudjak.bsky.social) Lab who was awarded the 2025 John W. Strohbehn Medal for Excellence in Biomedical Research!! 🤩 guarinigrad.dartmouth.edu/blog/2025/06...
Great piece on @stanford-chemh.bsky.social Institute Scholar @stanleyqilab.bsky.social’s work toward curing diseases with genome editing innovations #ResearchMatters
Stanford University@stanford.edu · last yr.“Research is like a chemical reaction – it takes time to reach completion. If we ever slow down in training the next generation of scientists, we risk falling behind other competitors in the world – even if we have the better solution.” #ResearchMatters
Switzerland🇨🇭 is an associated country and provides an excellent environment for research! This is a great opportunity if you’re ready for a move
European Research Council (ERC)@erc.europa.eu · last yr.Today, the ERC formally adopted a decision to increase its support for researchers moving to Europe. On top of its normal grants, the ERC offers 'start-up' funding to help PIs establish laboratories / research teams in Europe. This extra funding is now x2 (up to €2 million!) europa.eu/!6Vdgmp
Heterogeneous human AM subsets have counterparts in mice! Nice work from @claudjak.bsky.social lab
ATS Red Journal@ajrcmb.bsky.social · 2y agoThe Heterogeneity, Parallels, and Divergence of Alveolar Macrophages in Humans and Mice This study reveals complex heterogeneity in mouse AMs, highlighting conserved and unique subsets across humans and mouse @xinli0419.bsky.social @claudjak.bsky.social #macrophages 🔗 tinyurl.com/yb66ch6e
