We are so happy to see Vasanthi Jayaraman named chair of Biochemistry at UTHouston Vasanthi is not only a leader in biophysics and Editor-in-Chief of the Biophysical Journal, but also a wonderful colleague and mentor Congratulations @frettinglab.bsky.social med.uth.edu/blog/2026/04...

Excited to share our new paper in Science Advances @science.org In this work, we uncover how a disease-linked TRPC3 mutation, together with a cerebellum-specific splice isoform, stabilizes the channel in an open state, drives Calcium overload, and promotes neurodegeneration. (1/4)

Functional and structural basis of a hypermorphic TRPC3 variant

Structural snapshots capture an ataxia-linked overactive ion channel in its open state and reveal a druggable site for inhibition.

science.org

Sudha (@chakrapanilab.bsky.social) and Julio (@cvlab.bsky.social) are organizing the 2026 Ion Channel Gordon Research Conference: Ion Channels Across Scales — Bridging Molecular Events to Physiological Outcomes, to be held at Mount Holyoke College, July 12–17, 2026. 1/3

The Cordero Vásquez Lab is starting the year on a high wheel (see below) with our latest work on the C. elegans PIEZO channel: “Structures of invertebrate PEZO-1 isoforms with a compact architecture and a dispensable pore-distal N-terminal blade”: www.sciencedirect.com/science/arti... 1/5

Structures of invertebrate PEZO-1 isoforms with a compact architecture and a dispensable pore-distal N-terminal blade

PIEZO channels are mechanosensitive ion channels conserved from plants to humans, yet structures exist for only a few mammalian orthologs. We define t…

sciencedirect.com

Our new Journal of Neuroscience paper "Cofilin Inhibition Ameliorates PIEZO2 and AMPA Dysfunction in a Mouse Model of Angelman Syndrome (AS)” is out: www.jneurosci.org/content/45/4... 1/6

Cofilin Inhibition Ameliorates PIEZO2 and AMPA Dysfunction in a Mouse Model of Angelman Syndrome

Angelman syndrome (AS) is a neurogenetic disorder characterized by motor coordination and cognitive deficits. In AS, hippocampal neurons show reduced filamentous (F-)actin, a decrease we also reported...

jneurosci.org

Great series and this game7 was one of the greatest games Ive ever seen! Congrats Dodgers! Yamamoto has to be MVP of this series.

The Department of Biochemistry and Molecular Biology at UTHealth Houston has an open search for a tenure-track faculty position. If you are ready (or know someone that is) to start looking for positions, this will be a great opportunity to join the Texas Medical Center. See flyer below. 1/2

The Nobel Peace Committee sent a clear message to someone else in awarding the Prize to Ms. Machado: ”But democracy is also in retreat internationally. Democracy – understood as the right to freely express one’s opinion, …is the foundation of peace both within countries and between countries.” 👏

“The Nobel Peace Prize for 2025 goes to a brave and committed champion of peace – to a woman who keeps the flame of democracy burning amid a growing darkness.” www.nobelprize.org/prizes/peace...

Nobel Peace Prize 2025

The Nobel Peace Prize 2025 was awarded to Maria Corina Machado "for her tireless work promoting democratic rights for the people of Venezuela and for her struggle to achieve a just and peaceful transi...

nobelprize.org

Our new PNAS paper "Enhanced PIEZO1 function contributes to the pathogenesis of sickle cell disease" is out: www.pnas.org/doi/10.1073/... 1/3

Enhanced PIEZO1 function contributes to the pathogenesis of sickle cell disease | PNAS

Sickle cell disease (SCD), an inherited blood disorder caused by a mutation in the β-globin gene, is characterized by sickle erythrocytes that are ...

pnas.org

I’m so honored to be selected as both a 2025 McKnight Scholar and 2025 HHMI Freeman Hrabowski Scholar. And I couldn’t be prouder to share these honors with awesome @ucdavis.bsky.social colleagues 💙💛💙💛 health.ucdavis.edu/news/headlin...

UC Davis researchers honored by McKnight and Howard Hughes Medical Institute

UC Davis faculty Sergey Stavisky, Theanne Griffith and Elisa Zhang receive prestigious early-career recognition from McKnight Endowment Fund and the Howard Hughes Medical Institute.

health.ucdavis.edu

Such fantastic news! Congratulations!

Theanne Griffith, PhD 🇧🇧👩🏽‍🔬🇭🇷@doctheagrif.bsky.social · last yr.

I’m so honored to be selected as both a 2025 McKnight Scholar and 2025 HHMI Freeman Hrabowski Scholar. And I couldn’t be prouder to share these honors with awesome @ucdavis.bsky.social colleagues 💙💛💙💛 health.ucdavis.edu/news/headlin...

I spoke with Jade Hindmon, host of @kpbssandiego.bsky.social Midday Edition, about the consequences of the current administration’s cuts to science funding. Please share to help spread the word and raise awareness. www.kpbs.org/podcasts/kpb...

Nobel laureate on how Trump's cuts are hurting science

Neuroscientist, biologist and 2021 Nobel Prize winner Ardem Patapoutian joined Midday Edition to talk about how the Trump administration's effort to cut back on science spending is impacting researche...

kpbs.org

Colorado's Rep Brittany Pettersen (D) flew cross-country with her one-month-old to vote against the GOP budget tonight. Dems ended up one vote short. Pettersen was part of an unsuccessful bipartisan push to allow new mothers to vote remotely. #copolitics

My colleague Dan beat me to the punch but I am so thankful that my hometown paper (and others) was willing to share this with the community.

Daniel Gorelick@danielgorelick.bsky.social · last yr.

My colleague @rnareylab.bsky.social wrote this editorial for her hometown area newspaper. Well done & more please! www.heraldbanner.com/opinion/colu...

🚨🚨First paper of the year! I'm excited to share that our lab and collaborators have discovered that TRPV4/Cx43 hemichannels play a crucial role in endothelial hyperpolarization. Huge thanks to @piaburboa.bsky.social for continuing this fascinating work. physoc.onlinelibrary.wiley.com/doi/10.1113/...

The latest from @science.org on the situation at NIH. @meredithwadman.bsky.social and Jocelyn Kaiser getting all the info they can. www.science.org/content/arti...

NIH is purging Trump-targeted programs—but is sparing existing grants, so far

Chaos extends to CDC, which is shuttering websites in “data apocalypse”

science.org

If you have been affected by the fires in LA, or are concerned about your ability to keep precious Drosophila strains going during the latest funding crisis, we will host your strains as a backup. Please email me. Please amplify. If you are also able to host fly strains, add your name as well.

NSF has created an Executive Order Implementation webpage to ensure the widest dissemination of information and updates. We will continue to communicate with you as we receive additional guidance. new.nsf.gov/executive-or...

NSF Implementation of Recent Executive Orders

Information for the NSF community regarding executive orders.

new.nsf.gov

Please help us advertise this new opening 🧠 in our research group. I am happy to answer any queries about it.

Instituto de Neurociencias CSIC-UMH@neuroalc.bsky.social · 2y ago

The Sensory Transduction and Nociception Group @painchannels.bsky.social at @neuroalc.bsky.social offers a 1-year (extendable to 3) postdoctoral position. The call is open until the position is filled. More info 👇 in.umh-csic.es/en/ofertas/1...

While I realize this is not relevant to many of the present day discussions, the remarkable similarity of organisms at the biochemical, genetic, cellular, and physiological levels is not understood by many people. 1/n

The Channels, Receptors & Transporters Subgroup of the @biophysicalsoc.bsky.social is excited to announce the final program for our 2025 Symposium. Please join us on Feb 15 to hear from @willowcoyote.bsky.social @drcontrexin.bsky.social @corrylab.bsky.social and others 👇Thanks to our sponsors!

Just one month to go until the 2025 GRS/GRC in Molecular Pharmacology! Get ready for an extraordinary program packed with cutting-edge science and inspiring discussions. Full details here: www.grc.org/molecular-ph...

New paper‼️— from #PMB Griffith Lab! They show that sodium channels play unique roles in proprioceptive encoding. They also studied effects on skeletal muscle, and a dev dependent role for Nav1.6 in proprioceptive spinal circuits. www.science.org/doi/10.1126/...

Differential encoding of mammalian proprioception by voltage-gated sodium channels

Voltage-gated sodium channels differentially encode mammalian proprioception via distinct cellular localization patterns.

science.org

Thrilled to share the most recent pub from the Griffith Lab! We show that sodium channels play unique roles in proprioceptive encoding. We also found some really cool effects on skeletal muscle, and a dev dependent role for Nav1.6 in proprioceptive spinal circuits www.science.org/doi/10.1126/...

Differential encoding of mammalian proprioception by voltage-gated sodium channels

Voltage-gated sodium channels differentially encode mammalian proprioception via distinct cellular localization patterns.

science.org

Congratulations to #BlackInBiophysics Founder @stevenssostre.bsky.social and #BIBPS Board Member @jjalston.bsky.social on this extraordinary accomplishment!!! 🥳🥳🥳 We are PROUD of you and wish you the best in your careers! 👏🏾👏🏾👏🏾 @biophysicalsoc.bsky.social

HHMI@hhmi-science.bsky.social · 2y ago

Today we're thrilled to announce our 2024 #HannaGrayFellows! Please join us in welcoming and celebrating these outstanding early career scientists!

Está invitado para CIENCIA EN ESPAÑOL I am hosting an event where University of Arizona scientists will speak about their science in Spanish. It is meant to be a community event with a Zoom option, so share with family too! events.trellis.arizona.edu/en/f44lNu67/... #CIENCIAENESPAÑOL

How hard do bacteria-eating nematodes bite in order to break the bacterial cell wall? Check out our new paper, led by Jason Casar & collab with Jen Dionne, using pressure sensing beads that change color upon compression (bluetorial coming soon) rdcu.be/d5n7v

Upconverting microgauges reveal intraluminal force dynamics in vivo

Nature - Nanoparticle-based ‘microgauges’ are developed for in vivo force sensing and deployed in C. elegans to investigate how mechanical force correlates with electrical signalling in...

rdcu.be