Pleased to report we made the cover of the upcoming issue of Diabetologia for our most recent paper!! The effort was led by Ryan Hart (@ryanhart13.bsky.social). Description in the ALT text, full open acces link here: rdcu.be/fptyS
UC Davis Physiology
@ucd-physiology.bsky.social
Founded in 1966, the Department of Physiology and Membrane Biology is one of five basic science departments in the UC Davis School of Medicine. https://health.ucdavis.edu/physiology/
“JGP is also a journal I turn to for rigorous, impactful science, and it's wonderful when scientific excellence and a commitment to equity go hand in hand.”— Theanne Griffith (@doctheagrif.bsky.social). JGP, where scientists set the course 👉 hubs.la/Q04lcxPj0
📣 Call for Papers 📣 JGP welcomes papers on the topic of the @sgpweb.bsky.social 2026 meeting, “Membrane Excitability and Reproductive Biology,” to be published throughout the year and highlighted in a special issue! Learn more and submit here 👉 rupress.org/JGP/pages/ca...
So excited to serve as a Guest Editor w/ Professors Koichi Nakajo and Bikash Pattnaik for the upcoming special issue: @JPrecisionMed “Ion Channels in Precision Medicine: Mechanisms, Modeling and Therapeutic Innovation”
We are looking forward to your submissions! Reach out with a presubmission inquiry if you need more information!
📣Call for Papers: Ion Channels in Precision Medicine 🧑⚕️ Guest Editors: Koichi Nakajo, Bikash R. Pattnaik, and Colleen E. Clancy 📅 Deadline: 31 December 2026 👇️ More information: www.jprecisionmedicine.org/call-for-pap...
Our annual meeting is less than 2 months away! Join us at "Membrane Excitability and Reproductive Biology," with 9 sessions featuring 20 outstanding speakers. Several travel awards and speaking opportunities are available. Submit your abstract by 7 August to be eligible.
Join us for the next SGP EpIC Seminar on Tuesday, 7 July 2026, at 12:00 pm Eastern featuring a talk by Shanna Hamilton on “The cardiac ryanodine receptor: effects of calcium release beyond excitation-contraction coupling." As ever, registration is free and all are welcome: sgp-epic-seminars.com
🔥 NEW: Your blood vessels' calcium channels are secretly hitchhiking on microtubules 🚌 & in diabetes/hypertension, it goes haywire. 📜New paper from the team at @ucdavis.bsky.social, @ucdavispharm.bsky.social Check the thread for some cool movies 🎞️ physoc.onlinelibrary.wiley.com/doi/10.1113/...
physoc.onlinelibrary.wiley.com
“JUST-B was founded to create a more inclusive and equitable scientific community… JGP’s funding has been instrumental in allowing us to build and sustain the program.” Theanne Griffith (@doctheagrif.bsky.social) Share your work in a journal by and for scientists 👉 hubs.la/Q04lcxPj0
💊Check this out! Using human iPSC-derived sinoatrial node cells & 3D organoids, new study @CircAHA reveals how GLP1 directly accelerates the heart’s pacemaker. Collab with Lulu Ren (former @mcipucd.bsky.social) & Joe Wu's Lab @ucdavis.bsky.social www.ahajournals.org/doi/10.1161/...
Tirzepatide Regulates Pacemaker Function by Modulating cAMP and Calcium Dynamics in Human Sinoatrial Node Cells | Circulation
ahajournals.org
Full open access link here: rdcu.be/fptyS
Somatostatin receptors shape insulin and glucagon output within the pancreatic islet in mice through direct and paracrine effects
rdcu.be
New paper in @diabetologiajnl.bsky.social on paracrine control of insulin secretion, led by the talented newly minted Dr. Ryan Hart (@ryanhart13.bsky.social). 1/5 doi.org/10.1007/s001...
New paper in @diabetologiajnl.bsky.social on paracrine control of insulin secretion, led by the talented newly minted Dr. Ryan Hart (@ryanhart13.bsky.social). 1/5 doi.org/10.1007/s001...
Very proud to graduate the next group of supremely talented young Doctors from my UC Davis lab!! Dr. Mohammad Pourhosseinzadeh, Dr. Michelle Chan, and Dr. Ryan Hart. They each have published creative and impactful stories - much of it coming out soon. Stay tuned!! @ucdavis.bsky.social
🧪 I had a great chat with the two Bens @proteomicsnews.bsky.social and @benneely.com about all things muscle and tendon. Check out our and let me know if you have any questions.
For this week’s #THEProteomicsShow, me and Ben @proteomicsnews.bsky.social had the great pleasure of having Keith Baar @musclescience.bsky.social on to chat muscles and tendons. I know I keep saying it, but this was my fav. Find it wherever you find fine podcasts or here anchor.fm/theproteomic...
Another June, another crop of fantastic @ucdavis.bsky.social students who got leave their hand prints on the wall to celebrate their graduation from the Huising Lab. Congratulations to Hana, Nick, Ryan, Jacob, Frankie and visiting graduate student Jon!!
CPMDS Research Highlight 🔬 Computational models reveal how the autonomic nervous system regulates blood flow and blood pressure across molecular, cellular, and tissue scales, providing insights that could guide future precision cardiovascular therapies.
Smooth signals: computational insights into autonomic vascular control | American Journal of Physiology-Cell Physiology | American Physiological Society
The regulation of vascular tone underlies normal cardiovascular homeostasis, ensuring appropriate distribution of blood flow to tissues and maintenance of blood pressure. Computational modeling and si...
journals.physiology.org
Today! Kafui Dzirasa, MD, PhD from Duke University Medical Center will speak on 'Discovering and regulating brain dynamics relevant for emotions' at the 2026 Carlson Lecture.🎙️🧠 12pm in the Genome Auditorium, room 1005. Description: Portrait photo of the lecture speaker
Tomorrow! June 4—Kafui Dzirasa, MD, PhD from Duke University Medical Center will be our distinguished speaker at the 2026 Carlson Lecture.🎙️🧠 Join us at 12pm in the Genome Auditorium, room 1005. Description: Portrait photo of the lecture speaker
Join us for the 2026 Carlson Lecture, with speaker Kafui Dzirasa, MD, PhD from Duke U. Medical Center. Learn how engineered neural circuits may restore healthy brain function and help prevent psychiatric disorders. Thursday, June 4th, 12pm, Genome Auditorium Description: Photo, scientist smiling
New publication in Nucleic Acids Research describing CATVariant, an open-access web server for integrated protein variant interpretation. 🔗 Read the paper: doi.org/10.1093/nar/... 🌐 Try CATVariant: catvariant.com #Bioinformatics #PrecisionMedicine #Genomics #ProteinVariants #NAR #OpenScience
CATVariant: a web server for integrated protein variant interpretation across sequence, structure, population, and clinical evidence
Abstract. Efficient interpretation of the structural, functional, and clinical impact of protein variants remains a longstanding challenge. This difficulty
doi.org
CPMDS Research Highlight 🔬 CATVariant is a new open-access webserver for studying genetic variants, integrating population, clinical, structural, and literature data with computational predictors to help interpret variant effects. Read more: doi.org/10.1093/nar/... | Explore: catvariant.com
Yesterday's Basic Sciences Departmental Research Forum brought together faculty from BMM, CBHA, Pharmacology, and PMB. It was wonderful to share discoveries, spark new conversations, and strengthen cross-departmental collaboration. Description: Four photos of faculty at podium.
Read more: pubmed.ncbi.nlm.nih.gov/41083200/
Ligand Dissociation Pathways from Membrane Receptors Revealed by Weighted Ensemble Simulations - PubMed
G-protein-coupled receptors (GPCRs) are pivotal in cellular signal transduction and serve as key drug targets. Among them, the β-adrenergic receptors (β<sub>1</sub>AR and β<sub>2</sub>AR) regulate car...
pubmed.ncbi.nlm.nih.gov
👋The fourth episode of our podcast series just dropped. navedolab.faculty.ucdavis.edu/podcasts/ This one identifies a tissue-specific signaling mechanism that distinguishes how heart and vascular muscles control calcium intake. Check out the paper here: ahajournals.org/doi/10.1161/...
Podcasts – Welcome to the M&M Lab
navedolab.faculty.ucdavis.edu
Join us for Alexander Kehl's exit seminar!! 🎉 🔬 "Exploration of Rubisco Oligomeric State and Sequence Space" Join us to support Alex and hear about his fantastic research with the labs of Dr. Justin Siegel & Dr. Patrick Shih! 📅 Monday, June 1st at 11:00 AM 📍 Genome Center Auditorium
Join us for the next SGP EpIC Seminar on Tuesday, 2 June 2026, at 12:00 pm Eastern featuring a talk by Wojciech Kopec on “Computational electrophysiology of potassium channels.” As ever, registration is free and all are welcome: sgp-epic-seminars.com
CPMDS Research Highlight 🔬 (Drs. Igor Vorobyov, Vladimir Yarov Yarovoy, Colleen E. Clancy) Researchers used advanced simulations to reveal how ligands dissociate from membrane receptors, uncovering hidden molecular pathways that could improve drug discovery and precision therapeutics. 💻
Congratulations! #PMB health.ucdavis.edu/insideout/ne...
School of Medicine announces 2026 Cultivating Team Science Awards
The School of Medicine recently announced Laura Borodinsky, professor in the Department of Physiology & Membrane Biology and Clifford Pereira, professor in the Department of Surgery, as the 2026 recip...
health.ucdavis.edu
🔬 CPMDS Research Highlight (Dr. Pei-Chi Yang) New eLife research introduces AI-powered “digital twins” of heart cells, using synthetic data and electrophysiology to predict cell-specific behavior. This work could advance precision medicine, drug safety testing, and arrhythmia research.
Large-scale synthetic data enable digital twins of human excitable cells
elifesciences.org
Excited to share our new paper! This work explores how Sonic hedgehog signaling helps coordinate retinal patterning and neurogenesis, including regulation of both cell cycle exit and progenitor competence during mammalian eye development journals.biologists.com/dev/article/...
Roles of sonic hedgehog signaling in retinal patterning and neurogenesis during mammalian eye development
Summary: Temporal disruption of sonic hedgehog signaling reveals stage-specific roles in eye cup patterning and in regulating proliferation, progenitor competence and fate specification during retinal...
journals.biologists.com