New preprint from @anadopico.bsky.social (who I have had the great pleasure of supervising with Tom Milne) and our fantastic collaborators in the @davieslab.bsky.social www.biorxiv.org/content/10.6... #genomics #GeneRegulation #chromatin

Excited to share that a part of my PhD work is online now on BioRxiv! www.biorxiv.org/content/10.6... We developed a genome editing approach to target the JAK2 V617F mutation and demonstrate its potential to alleviate MPN hallmarks in primary patient cells. Thread 👇

Thanks so much for highlighting our images created with @rcollepardo.bsky.social

Biomedical Picture of the Day BPoD@bpodaily.bsky.social · 8mo ago

Mapping chromatin's structure at base-pair resolution reveals how it mediates cis-regulatory element interactions 📹 Hangpeng Li et al @jojdavies.bsky.social, MRC Molecular Haematology Unit, @imm.ox.ac.uk @ox.ac.uk in @cellpress.bsky.social ➡️ bpod.org.uk/archive/2025...

#WIMMReads: Oxford scientists, led by James Davies at the MRC WIMM, have captured the genome’s structure in unprecedented detail. 🧪 Read the full story below 👇 @ox.ac.uk @davieslab.bsky.social @jojdavies.bsky.social @medsci.ox.ac.uk

Radcliffe Department of Medicine@rdm.ox.ac.uk · 9mo ago

Scientists have the most detailed view yet of how DNA folds and functions inside living cells! The breakthrough helps us understand how genetic differences lead to disease and opens up fresh routes for drug discovery 👇 shorturl.at/nQjsx @jojdavies.bsky.social @imm.ox.ac.uk @medsci.ox.ac.uk

Our new preprint 🧬🔗 www.biorxiv.org/content/10.1... BRD4-NUT forms liquid-like condensates that locally constrain nucleosomes via BRD4-mediated crosslinking— physical control of #chromatin by #LLPS transcription condensates. @semeigazin.bsky.social @katsuminami.bsky.social @masaashimazoe.bsky.social

We’re really excited to see Hangpeng Li present our latest work at the CSH Mechanisms of Eukaryotic Transcription meeting.

In Brief: A new center in San Francisco will offer tailor-made CRISPR therapies to cure children with rare diseases www.nature.com/articles/s41...

Thrilled that our paper is in print @science.org!! *Platelets sequester cell free DNA, including free fetal and tumour-derived DNA* Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight

By sucking up DNA, clot-producing platelets could help diagnose cancer

The cells could be a new source of tumor DNA for liquid biopsies

science.org

Lauren Murphy@l-cmurphy.bsky.social · 12mo ago

🚨 New paper alert! 🚨 I’m thrilled and proud to share that our latest work has just been published in @science.org! 🎉 🧽 📖 Read our paper here: doi.org/10.1126/sci... 🎬 Watch a summary: youtu.be/MttCA3GGWEM 🧵 Or keep reading for the key points! 🔑 1/19

⚡️Thrilled that #VirtualLab is published in @nature.com! www.nature.com/articles/s41... We created a team of AI agents to mirror my Stanford lab 🤖. Led by a PI agent, the AI scientists ran their own group meetings and discovered effective binders to new CoVID variants that we validated.

Great news for the Advanced Proteomics Facility based here in Biochemistry @ox.ac.uk ! The Wolfson Foundation is supporting the acquisition of a state-of-the-art mass spectrometer – the first of its kind in the UK – opening up possibilities for breakthroughs in human health ⬇️ bit.ly/202507-apf

£840,000 award from the Wolfson Foundation to enhance Oxford’s proteomics research

State-of-the-art mass spectrometer to be installed at the University’s Advanced Proteomics Facility (APF)

bit.ly