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Daniel Fazakerley

@dfazakerley.bsky.social

Associate Professor at the University of Cambridge, Metabolic Cell Biology

3 Posts316 Follower219 Folgt
Atul Deshmukh@adeshmukh.bsky.social · 2mo ago

Publication Alert - Our latest study identifies sex- and fibre type-specific responses to resistance training and implicates CSRP3 in muscle hypertrophy. doi.org/10.1038/s414...

Sex- and fiber type-specific remodeling of the muscle proteome implicates CSRP3 in resistance training-induced hypertrophy - Nature Communications

Here, the authors show that changes in the muscle fiber proteome following 8 weeks of resistance training are both sex- and fiber type-specific. This includes greater upregulation of CSRP3 in type II ...

doi.org

Jason Cantor@jasonrcantor.bsky.social · 2y ago

🚨 pleased to share a new preprint made possible through a fantastic collaboration with the Skala & Palecek labs! can medium composition impact the behavior of hPSC-derived cardiomyocytes? Andy & Aaron co-led efforts to tackle this question w/HPLM! tinyurl.com/ux2arjw8

Human Plasma-Like Medium Promotes Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes

Maturing human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) in vitro is critical for advancing drug discovery and cardiotoxicity screening applications of these cells. However, the metaboli...

tinyurl.com

Adam Wołowczyk@awolowczyk.bsky.social · 2y ago

I'm delighted to be hosting the Cambridge University Endocrinology Society's annual conference this Friday, entitled: 'From Bench to Bedside (and back again)'. We're really fortunate to have such an exciting line up of speakers, integrating across a wide range of career stages and fields.

A set of four hand-drawn anatomical illustrations, each framed in a square with different background colors. The top left shows the pancreas with surrounding blood vessels and the gallbladder. The top right features the thyroid gland and larynx. The bottom left illustrates the kidneys, adrenal glands, and major blood vessels. The bottom right displays a cross-section of the human brain with detailed internal structures.A conference programme listing sessions, speakers, and topics related to endocrinology, metabolism, and medical innovation. The schedule includes a keynote on incretins, sessions on clinical translation, fundamental science, and innovation, with discussions on genes, metabolic monitoring, parental plasticity, diabetes management, and obesity drug development. The day concludes with prizes and closing remarks.
Daniel Fazakerley@dfazakerley.bsky.social · 2y ago

We have a postdoc position available in our team to undertake a UKRI-funded project to develop a new cultured skeletal muscle model for studying glc metabolism and insulin action. www.jobs.cam.ac.uk/job/50597/ @ims-mrl.bsky.social Please RT. Please email if interested.

Post-doctoral Research Associate (Fixed Term) - Job Opportunities - University of Cambridge

Post-doctoral Research Associate (Fixed Term) in the Department of Clinical Biochemistry at the University of Cambridge.

jobs.cam.ac.uk

Daniel Fazakerley@dfazakerley.bsky.social · 2y ago

Pleased to share our @cp-cellmetabolism.bsky.social forum on why we think standard cell culture practices deserve more consideration. How we culture cells has implications for cell metabolism & beyond! With @jasonrcantor.bsky.social @joycelyntan.bsky.social authors.elsevier.com/a/1klN65WXUl...

authors.elsevier.com

Jason Cantor@jasonrcantor.bsky.social · 2y ago

happy to share our forum now online @Cell_Metabolism! fun for us (Guy & myself) to collaborate with @dfazakerley.bsky.social, Joycelyn, & Sam in putting together what we hope will be a useful piece for the broad metabolism community re: in vitro modeling! www.cell.com/cell-metabol...

Giles Yeo@gilesyeo.bsky.social · 2y ago

Anyone interested in working with me at Institute of Metabolic Science - Metabolic Research Laboratories, University of Cambridge, on how AMGEN's new obesity drug MariTide works? I have a 3 year postdoc position available! Deadline March 31st! please share www.jobs.cam.ac.uk/job/50529/

Research Associate (Fixed Term) - Job Opportunities - University of Cambridge

Research Associate (Fixed Term) in the Department of Clinical Biochemistry at the University of Cambridge.

jobs.cam.ac.uk

Jason Cantor@jasonrcantor.bsky.social · 2y ago

excited to share a new preprint from our lab! led by the outstanding (& newly minted PhD) @thebiokimist.bsky.social we first uncover a basis for conditional HK2 essentiality in HPLM - leveraging this dependence then leads us to distinct rationale underlying why the Warburg Effect is beneficial!

bioRxiv Cancer Bio@biorxiv-cancer.bsky.social · 2y ago

Hexokinase detachment from mitochondria drives the Warburg effect to support compartmentalized ATP production https://www.biorxiv.org/content/10.1101/2025.02.07.637120v1