New paper in @natmetabolism.nature.com from @TVPLab @cam.ac.uk & @ebi.embl.org shows that #MASLD progresses as a continuum not in fixed stages, and describes a blood test pinpointing where a patient sits on that trajectory, pointing to earlier, more precise diagnosis. bit.ly/4wGlswE
Institute of Metabolic Science-Metabolic Research Laboratories
@ims-mrl.bsky.social
Research institute based at the University of Cambridge specialising in diabetes, obesity and related endocrine and metabolic disorders.
Hospitals face greater backlash when AI makes mistakes than doctors alone New paper in @nature.com's npj Digital Public Health, by Jungmin Choi from the @ims-mrl.bsky.social and @jbs.cam.ac.uk 👀https://www.mrl.ims.cam.ac.uk/news/hospitals-face-greater-backlash-when-ai-makes-mistakes-doctors-alone-0
Volunteers needed for two new exciting studies at @ims-mrl.bsky.social @cuh.nhs.uk @cam.ac.uk looking at the timing of eating habits and #metabolichealth, led by Dr Maria Chondonikola See more details below or contact: 📧 cuh.nutritionrs@nhs.net 📞 07523 268691
We are delighted to welcome Dr Claudia A Doege from @columbiauniversity.bsky.social Irving Medical Center who is visiting the @ims-mrl.bsky.social today to deliver our Tuesday seminar on 'Functional genomics of human obesity' and to meet with PIs, post-docs and students.
We are delighted to welcome Professor Ana Domingos from @ox.ac.uk who is visiting the @ims-mrl.bsky.social today to deliver our Tuesday seminar on 'Sympathetic circuits in obesity' and meeting with PIs, post-docs and students.
Want to know what health #research is happening in the East of England? Find out at the Patient & Public Involvement (PPI) showcase, 16 June at @cambridgebiocampus.bsky.social. With latest research talks, poster exhibition, networking & refreshments. Book your FREE ticket now bit.ly/NIHREoEPPI26...
Meet Abbexa at the Institute of Metabolic Science on 21 May 2026! Come and discover our latest reagents, speak directly with our scientists, and pick up free Abbexa goodies (including our popular grey felt bags). 📍IMS Tea Room, Level 4, @ims-mrl.bsky.social 📅21 May 2026, 9:30 am – 4:00 pm
We are delighted to welcome Dr Eleanor Raffan to the @ims-mrl.bsky.social today where she will be presenting our regular Tuesday seminar entitled 'Canine Clues to Human Obesity: Genetic and Physiological Insights' as well as meeting some of our PIs, postdocs and students.
Online Now: Physiological mechanisms mediating socio-environmental influences on pregnancy outcomes in Black people #trends #endocrinology #metabolism
Physiological mechanisms mediating socio-environmental influences on pregnancy outcomes in Black people
Black women and their infants experience higher mortality rates than their White counterparts. While systemic racism, socioeconomic disadvantage, and environmental stressors are recognized contributors, physiological pathways that mediate their effects on health disparities remain poorly understood. This review explores mechanisms through which stress-related epigenetic processes may contribute to more adverse pregnancy outcomes in Black women. Increased uteroplacental vascular resistance, oxidative stress, and inflammation are established mechanisms associated with leading causes of maternal and infant mortality, but there are differences in the expression of these mechanisms between Black and White women. We propose that these differences, which may reflect differences in social and environmental exposures, can help to explain the disparity in maternal and infant mortality rates between Black and White people.
dlvr.it
An important paper from Professor Dino Giussani's group (an affiliated PI with @ims-mrl.bsky.social)
Black women in the UK are almost three times more likely to die in, or just after, pregnancy than white women. These are not due to genetic differences. Societal stressors affect the body’s ability to function healthily during pregnancy. Read more: https://bit.ly/4ty0QWl
Somatic mutations in autoimmune lymphocytes may allow them to escape tolerance constraints through a polyclonal cascade of somatic evolution @nature.com @sangerinstitute.bsky.social @ims-mrl.bsky.social @cuh.nhs.uk @imartincorena.bsky.social www.nature.com/articles/s41...
🔦 New Paper Scientists in Cambridge undertook genetic analysis to reveal how somatic mutations contribute to autoimmune diseases in the thyroid gland. Published in Nature and led by Pantelis Nicola @sangerinstitute.bsky.social, Nadia Schoenmakers & John Tadross @ims-mrl.bsky.social @cuh.nhs.uk
👀 Interested in studying at the @ims-mrl.bsky.social for an MPhil in Obesity, Endocrinology and Metabolism?? 💊 🔬 🧫 🧪 🥼 The deadline for applications for our October 2026 intake is only 2 days away on 15 April. Don't delay 👉 More details on our website www.mrl.ims.cam.ac.uk/study-us/mphil
The IMS & Pint of Science UK present a conversation on nutrition & health with doctor/broadcaster Christoffer van Tulleken, doctor/food writer/Masterchef 2017 winner Saliha Mahmood-Ahmed and me! We are at The Junction in Cambridge on June 3. Tickets on sale NOW! www.junction.co.uk/events/a-con...
Many congratulations Sadaf from your colleagues at @ims-mrl.bsky.social, @cam.ac.uk, @cuh.nhs.uk, @cambridgebrc.bsky.social. Very well deserved More details 👇 www.mrl.ims.cam.ac.uk/news/obesity...
Obesity Prize for Excellence awarded to Professor Sadaf Farooqi for distinguished and innovative work in obesity and Its complications | Institute of Metabolic Science
We are delighted to announce that Professor Sadaf Farooqi is the 2026 recipient of the European Association for the Study of Obesity (EASO) - Novo Nordisk Foundation (NNF) Obesity Prize for Excellence...
mrl.ims.cam.ac.uk
European Association for the Study of Obesity (EASO) and Novo Nordisk Foundation congratulate the Obesity Prize for Excellence Award Winner - Professor Sadaf Farooqi from the United Kingdom Read about her award and research here: easo.org/obesity-priz...
Prof Giles Yeo @ims-mrl.bsky.social and Prof Nita Forouhi at @imsepidemiology.bsky.social return to join Professor Brian Cox for a deeper dive into the science of nutrition on the BBC @crick.ac.uk Question of Science podcast. Listen at buff.ly/VIcWOY2
This #WorldObesityDay members of the @ims-mrl.bsky.social made the #OforObesity at key Cambridge landmarks! Obesity is a complex medical condition, and our researchers study the biological, genetic, and environmental factors that contribute to obesity. #8BillionReasons #ActOnObesity
Today we celebrate the International Day of Women and Girls in Science #WomenInScience #IDWGIS #IMS_MRL #WomenInSTEM #CambridgeScience
Starting on 9 Feb - BBC Radio 4's The Hunger Game is a 5 part series presented by Prof @gilesyeo.bsky.social from the @ims-mrl.bsky.social, exploring the GLP-1 weight loss drug revolution - their development, the latest research and the marketing strategy behind them. www.bbc.co.uk/programmes/m...
BBC Radio 4 - The Hunger Game
A series exploring the weight loss drug revolution. Presented by Professor Giles Yeo.
bbc.co.uk
Editor's Choice Paper by @jmschoonejans.bsky.social @ozannelab.bsky.social 'Balancing maternal benefits and cardiovascular risks of metformin during pregnancy' now includes a video short by Josca www.youtube.com/watch?v=H2aB... Read paper - onlinelibrary.wiley.com/doi/full/10....
Exploring the cardiovascular outcome in the offspring of metformin-treated obese mice
YouTube video by The Physiological Society
youtube.com
Congratulations to Professor Roman Hovorka from the @ims-mrl.bsky.social on being awarded the 2025 Manpei Suzuki International Prize for Diabetes Research in recognition of his pioneering research in closed-loop insulin delivery systems in type 1 diabetes. manpeisuzukiprize.org/winners/2025...
Congratulations to Dr Charlotte Boughton from the @ims-mrl.bsky.social on being selected to deliver the RD Lawrence Lecture at the @diabetesuk.bsky.social Professionals conference in 2027!
Constanza Alcaino et al. from @ims-mrl.bsky.social present this #SymposiumReview discussing #incretin hormones and #obesity 💉 🔎 🔗 Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Congrats Ellie
Congratulations to PhD student Ellie Fox who has been awarded the EMBO Journal Poster Prize, at the UK Membrane Trafficking Meeting 2025. Ellie's PhD is a collaborative project with @dgershlick.bsky.social lab, Daniel Fazakerley @ims-mrl.bsky.social & Morag Rose Hunter @astra-zeneca.bsky.social
Don't forget to catch our behind-the-scenes look at life in the lab at the @ims-mrl.bsky.social, meet researchers and hear about cutting-edge science. 👀 Check out Instagram -https://instagram.com/ims_mrl/ TikTok - tiktok.com/@imsmrl YouTube-https://youtube.com/shorts/9uhrvUp
Interesting article by the BBC about obesity featuring Prof Sadaf@farooqi-lab.bsky.social who suggests "the amount of weight people gain is significantly influenced by their genes and those genes are relevant for everybody" www.bbc.co.uk/news/article...
Why some people really struggle to lose weight more than others
Thousands of genes that have an influence on weight, say experts - which means weight loss isn't a level playing field
bbc.co.uk
Want a behind-the-scenes look at life in the lab at the @ims-mrl.bsky.social, meet researchers and hear about cutting-edge science? 👀 Check out 👉 Instagram - instagram.com/ims_mrl/ or 👉 TikTok - tiktok.com/@imsmrl Here's a taste ⬇️⬇️⬇️ youtube.com/shorts/9uhrv...
Interested in studying for a PhD or MPhil at the @ims-mrl.bsky.social - don't leave it too late, the deadline if you want University funding is 2nd December Have a look now at what we can offer 👇👇👇 PhD - mrl.ims.cam.ac.uk/study-us/phd MPhil - mrl.ims.cam.ac.uk/study-us/tau...
In our final @ims-mrl.bsky.social external seminar for this term, Professor Ivan de Araujo from the @mpicybernetics.bsky.social in Germany is talking to us about the 'Gut-Brain Mechanisms of Hunger'