A belated but very well deserved congratulations to postdoc @elliottbernard.bsky.social for his poster prize at the Gordon Cell Death conference! ++ a shoutout to Alexis for his poster and new work!
Department of Immunobiology at UNIL
@dib-unil.bsky.social
Official account of the department of immunobiology (DIB) at the university of Lausanne @UNIL. Formerly department of biochemistry.
Congratulations @miriamlisci.bsky.social for her @fbm-unil.bsky.social Young Researcher in Basic Science award!
Miriam Lisci@miriamlisci.bsky.social · 2mo agoIt was an honour to be selected for the Young Researcher in Basic Sciences Award by the Faculty of Biology and Medicine @unil.bsky.social! A sincere thank you to my department @dib-unil.bsky.social for the support, and especially to my wonderful colleagues at the @jourdainlab.bsky.social
Congratulations to @mmonguio.bsky.social a recipient of the 2026 ECCO grant to study SLC15A4/TASL signalling in Inflammatory Bowel Diseases (IBD) in the Rebsamen lab @rebsamenlab.bsky.social rebsamenlab.org/marta-mongui...
Congratulations to @jourdainlab.bsky.social on his recent tenure confirmation and well deserved promotion! 🥳 @unil.bsky.social @fbm-unil.bsky.social
A new study out by Nagham and colleagues from the Luther lab hot off the press! @dib-unil.bsky.social
@fbm-unil.bsky.social · 3mo ago👮🎼 A research group @dib-unil.bsky.social @fbm-unil.bsky.social @unil.bsky.social has discovered that a #fibroblast subtype is essential for coordinating certain #immune #cells within #lymph #nodes. Press release here 👉 www.unil.ch/news/en/1776...
We’re happy to share our updated manuscript on Ninj1, incorporating measurements of membrane tension, cellular assays of ninj1 and ninj2 dimer stability and MD simulations of ninj1 oligmers opening and forming (see below!). @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...
🦠🔬 L'équipe du Pr Petr Broz @brozlab.bsky.social @dib-unil.bsky.social @fbm-unil.bsky.social @unil.bsky.social a identifié un mécanisme jusqu'alors inconnu par lequel le système immunitaire détecte l'endotoxine, un composant clé des membranes bactériennes. ➡️ www.unil.ch/news/fr/1769...
Notre système immunitaire «presse» les bactéries pour mieux les repérer
L'équipe du Pr Petr Broz, au Département d'immunobiologie de l’Unil, a identifié un mécanisme jusqu'alors inconnu par lequel le système immunitaire détecte l'endotoxine, un composant clé des membranes...
unil.ch
🥜🦀 A research group @jourdainlab.bsky.social @dib-unil.bsky.social @fbm-unil.bsky.social @unil.bsky.social has identified a new mechanism that exposes the vulnerability of #tumor #cells when they are deprived of #vitamin B7, also known as #biotin. Press release here 👉 www.unil.ch/news/en/1770...
Vitamins: a tool to exploit against cancer
A research group at Unil has identified a new mechanism that exposes the vulnerability of tumor cells when they are deprived of vitamin B7.
unil.ch
New article in Molecular Cell by @miriamlisci.bsky.social and @jourdainlab.bsky.social!
Alexis A. Jourdain@jourdainlab.bsky.social · 5mo agoOur story on #FBXW7 and #biotin in #glutamine_addiction is now peer-reviewed and published in Molecular Cell! Heroic work led by the very first postdoc of the lab @miriamlisci.bsky.social. Have a look! www.cell.com/molecular-ce...
Groups of: Petr Broz@brozlab.bsky.social Peter Draber Julia Esser-von Bieren Ella Hartenian@ehartenian.bsky.social Alexis Jourdain@jourdainlab.bsky.social Sanjiv Luther Fabio Martinon@martinon.bsky.social Andreas Mayer Manuele Rebsamen@rebsamenlab.bsky.social Pascal Schneider Margot ThomeMiazza
We're thrilled to share the lab's latest publication demonstrating how caspase-4 and the non canonical inflammasome recognize cytosolic LPS by preferentially binding to the convex portions of membranes - both bacterial and micelles @cp-immunity.bsky.social www.sciencedirect.com/science/arti...
Caspase-4 binds to LPS membranes with positive curvature for non-canonical inflammasome activation
The non-canonical inflammasome, comprising caspase-4 in humans, initiates pyroptosis upon sensing cytosolic lipopolysaccharide (LPS) from Gram-negativ…
sciencedirect.com
Join us for the upcoming innate immunity keystone. There’s a great lineup of speakers. @keystoneSymposia.bsky.social #InnateImmunity : Diversity in #HostDefense & Disease, this March! keysym.us/KSInnateImmune26 #KSInnateImmune26
Congratulations to Sina Bohnacker for her new grant. Exciting science ahead! www.unil.ch/news/en/1767...
Attribution des Transition Grants 2025: lauréates FBM
Le Décanat de la Faculté de biologie et de médecine (FBM) de l'Unil adresse toutes ses félicitations aux cinq lauréates des Transition Grants.
unil.ch
10 days left to apply! 👇
Alexis A. Jourdain@jourdainlab.bsky.social · 9mo agoWe are hiring a postdoc! 🧪 ▶️ Project: nucleotide metabolism (genomics & biochemistry) ▶️ Start date: spring 2026 (flexible) ▶️ More info and application: tinyurl.com/3kjrbb2x Please share 🌏 @fbm-unil.bsky.social @dib-unil.bsky.social @unil.bsky.social @snsf.ch
One month left to apply to the open postdoc position in our lab! 👇
Alexis A. Jourdain@jourdainlab.bsky.social · 9mo agoWe are hiring a postdoc! 🧪 ▶️ Project: nucleotide metabolism (genomics & biochemistry) ▶️ Start date: spring 2026 (flexible) ▶️ More info and application: tinyurl.com/3kjrbb2x Please share 🌏 @fbm-unil.bsky.social @dib-unil.bsky.social @unil.bsky.social @snsf.ch
Annndddd it’s out! Here’s what came out of combining my virology background with the @brozlab.bsky.social’s cell death focus : a novel role for the cell death protein ninj1 during hsv1 infection. In brief, Ninj1 on mouse macrophages results in lower infection rates and higher cytokine secretion.
🚨 Join our lab - we are recruiting a PhD student! Application deadline: 20.12.2025 Starting date: from 1.04.2026 More info and application👇 Please share @dib-unil.bsky.social @fbm-unil.bsky.social #immunosky
Career Opportunities: Graduate assistant (PhD student) position Rebsamen Lab: Innate immunity and autoimmunity (22580)
career5.successfactors.eu
🎬 When #biology met #medicine... First episod 👉 Avec l'immunobiologiste Julia Esser-von Bieren et le médecin Antoine Reinhard Lire l'interview croisée www.unil.ch/news/fr/1764... @dib-unil.bsky.social @unil.bsky.social #chuv #fbm
Mémoire innée et inflammation chronique, une pelote de questions
Les agents de l’immunité innée, soldats de première ligne du système immunitaire, « apprennent » aussi : des scientifiques de l’Unil et du CHUV étudient les impacts de cette « mémoire innée » sur cert...
unil.ch
Join us! Still few days to apply to the open PhD position in our lab @dib-unil.bsky.social Lausanne🇨🇭! Deadline: 20.12.2025 More info👇 and www.rebsamenlab.org
Rebsamen Lab @UNIL@rebsamenlab.bsky.social · 9mo ago🚨 Join our lab - we are recruiting a PhD student! Application deadline: 20.12.2025 Starting date: from 1.04.2026 More info and application👇 Please share @dib-unil.bsky.social @fbm-unil.bsky.social #immunosky
Congratulations and welcome to Ella Hartenian @ehartenian.bsky.social, who will be launching her group in our Department of Immunobiology in 2026! www.unil.ch/news/fr/1764...
Trois récipiendaires Ambizione rejoignent la FBM
Cette année, trois jeunes scientifiques viennent renforcer la Faculté de biologie et de médecine (FBM) de l’Unil. Lauréat·es des subsides Ambizione du Fonds national suisse, Ella Hartenian, David Robe...
unil.ch
Thrilled and incredibly honored to be selected as an @embo.org Young Investigator! Still can’t quite believe it 🎉 Huge thanks to EMBO and to all the amazing mentors, colleagues, and collaborators who made this possible! @fbm-unil.bsky.social @unil.bsky.social @snsf.ch
EMBO@embo.org · 8mo agoCongratulations to the new cohort of 28 EMBO Young Investigators! They are joining an international network of more than 800 life scientists – Welcome! Read the press release here: https://www.embo.org/press-releases/twenty-eight-group-leaders-become-embo-young-investigators/
👏 Bravo à Alexis Jourdain qui rejoindra l’EMBO Young Investigator Programme @embo.org au 1er janvier 2026. L’initiative européenne soutient des scientifiques en début de carrière dirigeant leur propre équipe de recherche. 🔗 www.unil.ch/news/fr/1764... @jourdainlab.bsky.social @dib-unil.bsky.social
Alexis Jourdain nommé EMBO Young Investigator
Professeur assistant à la FBM, Alexis Jourdain a été sélectionné pour l’EMBO Young Investigator Programme. Cette distinction offre au spécialiste du métabolisme un soutien important pour consolider le...
unil.ch
Congratulations @jourdainlab.bsky.social 👏 @dib-unil.bsky.social @unil.bsky.social @embo.org
EMBO@embo.org · 8mo agoCongratulations to the new cohort of 28 EMBO Young Investigators! They are joining an international network of more than 800 life scientists – Welcome! Read the press release here: https://www.embo.org/press-releases/twenty-eight-group-leaders-become-embo-young-investigators/
Postdoc opportunity in @jourdainlab.bsky.social lab !
Alexis A. Jourdain@jourdainlab.bsky.social · 9mo agoWe are hiring a postdoc! 🧪 ▶️ Project: nucleotide metabolism (genomics & biochemistry) ▶️ Start date: spring 2026 (flexible) ▶️ More info and application: tinyurl.com/3kjrbb2x Please share 🌏 @fbm-unil.bsky.social @dib-unil.bsky.social @unil.bsky.social @snsf.ch
🔦 Flash #Recherche 🧬🦀 Des scientifiques @dib-unil.bsky.social @unil.bsky.social identifient un nouveau #mécanisme susceptible de faire dérailler certains #traitements du #cancer. En jeu ? La perte du gène 𝘕𝘜𝘋𝘛5. 🔗 www.unil.ch/news/fr/1762... @jourdainlab.bsky.social
Ce gène qui sauve les chimiothérapies
Des scientifiques du Département d’immunobiologie de l’Unil mettent en évidence un nouveau mécanisme susceptible de faire dérailler certains traitements du cancer.
unil.ch
New publication from Abigail Strefeler-Alexandre and @jourdainlab.bsky.social in Nature Metabolism!
Alexis A. Jourdain@jourdainlab.bsky.social · 9mo agoVery excited to share the published version of our #uridine #CRISPR screen in naturemetabolism.bsky.social! 🎉 Led by Abigail Strefeler with @pagliarini-lab.bsky.social @zakbaker.bsky.social and team! #NUDT5 #DMQ @dib-unil.bsky.social @fbm-unil.bsky.social 🔗 www.nature.com/articles/s42... 🧵1/17
The second day of the @dib-unil.bsky.social #PRR symposium kicks off with more excellent talks including our own Jakub Began.
Kicking off the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors organized by our department in Lausanne! @brozlab.bsky.social @martinon.bsky.social @rebsamenlab.bsky.social @fbm-unil.bsky.social
New manuscript by Marcell Harhai and the Jourdain lab! @marcellharhai.bsky.social @jourdainlab.bsky.social @fbm-unil.bsky.social @unil.bsky.social
Alexis A. Jourdain@jourdainlab.bsky.social · last yr.Our updated inventory of genes required for #OXPHOS & findings on #mito defects in #Menieres is now out at Cell Reports! 🎉 🧫 New galactose #CRISPR screen 🎯 481 genes required for #OXPHOS ⚙️ #FAM136A in IMS proteostasis 👂 Mito defects in #Menieres www.cell.com/cell-reports...