Here’s to an excellent @keystonesymposia.bsky.social conference in Hannover, Germany! A lovely location and great to see many new and familiar faces. Thanks to all for the excellent talks and stimulating discussion. #KSViral26

You can hear all about this in a few weeks in Canada where @ehartenian.bsky.social will be presenting it @keystonesymposia.bsky.social on Innate Immunity

We’re happy to share our updated manuscript on Ninj1, incorporating measurements of membrane tension, cellular assays of ninj1 and ninj2 dimer stability and MD simulations of ninj1 oligmers opening and forming (see below!). @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...

👏 Félicitations aux lauréat·es du programme #Ambizione 2024 @snsf.ch 👉 Ella Hartenian, David Robertson et Sivaniya Subramaniapillai, qui lancent leurs propres groupes de #recherche au sein de la faculté. 🔗 www.unil.ch/news/fr/1764... @ehartenian.bsky.social @sivaniya.bsky.social @unil.bsky.social

Trois récipiendaires Ambizione rejoignent la FBM

Cette année, trois jeunes scientifiques viennent renforcer la Faculté de biologie et de médecine (FBM) de l’Unil. Lauréat·es des subsides Ambizione du Fonds national suisse, Ella Hartenian, David Robe...

unil.ch

Congratulations and welcome to Ella Hartenian @ehartenian.bsky.social, who will be launching her group in our Department of Immunobiology in 2026! www.unil.ch/news/fr/1764...

Trois récipiendaires Ambizione rejoignent la FBM

Cette année, trois jeunes scientifiques viennent renforcer la Faculté de biologie et de médecine (FBM) de l’Unil. Lauréat·es des subsides Ambizione du Fonds national suisse, Ella Hartenian, David Robe...

unil.ch

Annndddd it’s out! Here’s what came out of combining my virology background with the @brozlab.bsky.social’s cell death focus : a novel role for the cell death protein ninj1 during hsv1 infection. In brief, Ninj1 on mouse macrophages results in lower infection rates and higher cytokine secretion.

November is a big month for the lab with *two* new papers by @ehartenian.bsky.social and @alexandraboegli.bsky.social ++ co authors now online. www.embopress.org/doi/full/10....

NINJ1 blocks HSV-1 entry into macrophages to impact viral replication and immunity | EMBO reports

imageimageNINJ1 blocks HSV-1 entry into mouse macrophages independent of its role in cell death, resulting in greater secretion of pro inflammatory cytokines downstream of infection. Mouse macrophages lacking NINJ1 are more permissive to HSV-1 ...

embopress.org

It’s DIB day! The annual conference for our department @dib-unil.bsky.social. Lovely day (and view!) at the Lausanne Olympic museum exchanging with our colleagues. Plus a stellar presentation on NINJ1 by our own @elliottbernard.bsky.social 🔬!

Kicking off the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors organized by our department in Lausanne! @brozlab.bsky.social @martinon.bsky.social @rebsamenlab.bsky.social @fbm-unil.bsky.social

No better time to call or email your members of Congress. Next year’s NIH budget is being debated in the Senate. A new nonpartisan campaign is making it easy to defend science and protect America’s innovation. Just follow this link to contact your representatives: www.protectscienceandinnovation.org

Protect Science and Innovation

protectscienceandinnovation.org

Xin Jin@xinjin.bsky.social · last yr.

Science and innovation drive every breakthrough. On 7/21, a nation-wide campaign kicks off to honor Apollo 11’s legacy -- tell Congress NO to research‑funding cuts. Speak up here: ProtectScienceAndInnovation.org #ProtectScience #InnovationMakesAmericaGreat

📣Save the date! 📣 We will be hosting the 18th Mini Herpesvirus Workshop and the HHV-65 Symposium in Freiburg this year. We are very excited about all of the amazing speakers that we get to welcome. We can't wait to see you all there!

🚨 URGENT RESPONSE CALL 🚨 Trump’s Fool’s Gold Science EO is a dangerous sham. It gives his appointees the power to dismiss entire bodies of research and punish researchers who fail to fall in line with his agenda. We’ve launched an open letter. SIGN & SHARE NOW: actionnetwork.org/petitions/op...

Sign The Open Letter to Stand Up For Science Now!

Science is under siege. Trump’s latest Executive Order calls for politically appointed science commissars to evaluate research. Join us in adding your name to our open letter condemning Trump’s escala...

actionnetwork.org

A new combination of microscopy methods has revealed exquisite details of the virus assembly process used by herpes simplex virus during replication. buff.ly/aO8W9BJ

Our research shows that ~50% of mothers globally decline at least half of opportunities to participate in conferences after becoming parents (N=3995). We understand the barriers and are offering Travel Grants to help overcome these challenges. Apply now - deadline 31st March! shorturl.at/gnCU2

Let's not forget that apart from science advocacy the Rauch lab also does kick-ass science! Together with the @psmitchej.bsky.social and Tait Wojno labs, we show that #tuftcells can induce specific protective signaling after recognition of intracellular bacterial infection via the #inflammasome!

Journal of Experimental Medicine@jem.org · last yr.

First authors Madeline Churchill and Ankit Pandeya @nkeet50.bsky.social from @rauchlab.bsky.social show that tuft cells, known for their role in anti-parasite defenses, can also contribute to anti-bacterial responses in the small intestine. rupress.org/jem/article/... #InfectiousDisease

I’m very excited to share our first preprint “Structural Basis for OAS2 Regulation and its Antiviral Function” from my postdoc together with Veronika Merold (Vroni) from NTase lab with @oliveiramann.bsky.social www.biorxiv.org/content/10.1...

SO MANY STAND UP FOR SCIENCE EVENTS TO CHOOSE FROM—153 and COUNTING! To get more information on our local events and to register your own, head to www.standupforscience2025.org/local-event-information/ ☀️⬇️🌎

Get in Dorks, we are going protesting. STAND UP FOR SCIENCE. MARCH 7th 12-4pm. DC AND YOUR STATE CAPITALS. More information to come.

Alt National Park Service@altnps.bsky.social · last yr.

NYGC is organizing a number of efforts to address the changes to NIH IDCs and other changes to federal policy. If you are a US citizen, or in the US working in science, please consider signing this petition. The more signatures the stronger our hand in interacting with law makers. chng.it/kK2HMP5pGk

Sign the Petition

Petition to Reverse the NIH Indirect Cost Cap (NOT-OD-25-068)

chng.it

Each week, we are collecting, reading, vetting & tagging all the links, news & rumors you’re seeing whiz past you online. We are also talking to dozens of researchers & PIs about their firsthand experiences. Every Friday, I debrief you over a drink at buttondown.com/liminalcreat...

Making Sense of It All

Hi! I’m Liz Neeley and I’m glad you’re here. Making Sense of It All is an outlet for my work at Liminal, which focuses on sensemaking in a noisy and complicated world. I built Liminal as an antidote t...

buttondown.com

The excellent Swiss Virology Meeting just ended. Thanks to the organizers and participants for making it such a warm and collegial environment. Here Magalie and I are with the project that began as her masters project. 🦠🚀

Happy to share the first preprint from my lab by @indrabekere.bsky.social and Veronika Merold! We solved the cryo-EM structure of the RNA immune sensor OAS2 and revealed how dimerization and subcellular localization regulate its activity! Check out Indra’s thread for a summary:

Indra_Beķere@indrabekere.bsky.social · 2y ago

I’m very excited to share our first preprint “Structural Basis for OAS2 Regulation and its Antiviral Function” from my postdoc together with Veronika Merold (Vroni) from NTase lab with @oliveiramann.bsky.social www.biorxiv.org/content/10.1...

We are excited to announce the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors, Oct 1-2 2025, Lausanne, Switzerland. Registrations open March 1 - Attendance limited to 150 participants. More info: wp.unil.ch/immunobiolog... #ImmunoSky

Check out our latest pre print! Alexandra and colleagues show that the enigmatic inflammasome receptor, NLRP6 is activated by sterile and pathogen induced endolysosomal damage. Hot off the press! www.biorxiv.org/content/10.1...

Sterile- or pathogen-induced endolysosomal damage activate the NLRP6 inflammasome in human intestinal epithelial cells

NLRP6 controls host defense against bacteria and viruses in the gastrointestinal tract by a poorly understood mechanism. Here, we report that NLRP6 forms an inflammasome upon endolysosomal damage caus...

biorxiv.org

For those who haven't been following the cozying up to RFK Jr. by some liberals (call them what you want, they are not Republicans) and why it's dangerous. Three pieces to lay out the case. 1/

The class gap in career progression: US academia First-generation college graduates are 13% less likely to end up tenured at an R1, and are on average tenured at institutions ranked 9% lower, than their PhD classmates with a parent with a (non-PhD) graduate degree. mitsloan.mit.edu/shared/ods/d...

MIT researchers introduce Boltz-1, a fully open-source model for predicting biomolecular structures With models like AlphaFold3 limited to academic research, the team built an equivalent alternative, to encourage innovation more broadly www.eurekalert.org/news-release...

MIT researchers introduce Boltz-1, a fully open-source model for predicting biomolecular structures

Researchers in the MIT Jameel Clinic for Machine Learning in Health developed a fully open-source biomolecular structure prediction model that achieves state-of-the-art performance, at the level of Al...

eurekalert.org

A new genomic study in Science encompassing more than 300 genomes spanning the last 50,000 years has revealed how a single wave of Neanderthal gene flow into early modern humans left an indelible mark on human evolution. scim.ag/4gkMvpz

Neanderthal ancestry through time: Insights from genomes of ancient and present-day humans

Gene flow from Neanderthals has shaped genetic and phenotypic variation in modern humans. We generated a catalog of Neanderthal ancestry segments in more than 300 genomes spanning the past 50,000 year...

scim.ag

It's that time of year. Confocal + Christmas = Xmas Tree, Ymas Tree, and our favorite Zmas tree. #microscopy #confocal #imaging

Interested in learning more about NINJ1? My colleagues in the @brozlab.bsky.social, including @ehartenian.bsky.social, wrote a nice review of our current knowledge. www.cell.com/trends/bioch...