Rebsamen Lab @UNIL
@rebsamenlab.bsky.social
Research lab, Dpt. of Immunobiology, University of Lausanne, Switzerland. #InnateImmunity, #autoimmunity, #solutecarriers. Views are my own. More info: www.rebsamenlab.org
📣 Job announcement: we have an open Postdoctoral position in the field of neural stem cell metabolism! Motivated candidates should apply through the official platform under this link, where you can also find more informations: career5.successfactors.eu/career?compa... Please help spread the word!
We're thrilled to share the lab's latest publication demonstrating how caspase-4 and the non canonical inflammasome recognize cytosolic LPS by preferentially binding to the convex portions of membranes - both bacterial and micelles @cp-immunity.bsky.social www.sciencedirect.com/science/arti...
Caspase-4 binds to LPS membranes with positive curvature for non-canonical inflammasome activation
The non-canonical inflammasome, comprising caspase-4 in humans, initiates pyroptosis upon sensing cytosolic lipopolysaccharide (LPS) from Gram-negativ…
sciencedirect.com
Join us! Still few days to apply to the open PhD position in our lab @dib-unil.bsky.social Lausanne🇨🇭! Deadline: 20.12.2025 More info👇 and www.rebsamenlab.org
Rebsamen Lab @UNIL@rebsamenlab.bsky.social · 9mo ago🚨 Join our lab - we are recruiting a PhD student! Application deadline: 20.12.2025 Starting date: from 1.04.2026 More info and application👇 Please share @dib-unil.bsky.social @fbm-unil.bsky.social #immunosky
🚨 Join our lab - we are recruiting a PhD student! Application deadline: 20.12.2025 Starting date: from 1.04.2026 More info and application👇 Please share @dib-unil.bsky.social @fbm-unil.bsky.social #immunosky
Career Opportunities: Graduate assistant (PhD student) position Rebsamen Lab: Innate immunity and autoimmunity (22580)
career5.successfactors.eu
Very happy to share that our research proposal has been funded by @snsf.ch ! 🎉 Grateful for the confidence in our work and excited for what this support will make possible. Big thanks to our amazing team and everyone who helped make it happen.
Swiss National Science Foundation (SNSF)@snsf.ch · 9mo ago💩🕵️ 💻 ⚖️ From improved wastewater treatment to new rules for digital evidence: With its largest funding scheme, the #SNSF is supporting 346 projects spanning the full spectrum of the Swiss research landscape with a total of 326 million francs. 💸💡 👉https://buff.ly/Iq17IFW
Happy to see our paper on the regulation of TLR biogenesis by CCDC134 featured in the JEM collection “Pattern Recognition Receptors and Beyond.” Check it out along with the other selected articles!
Journal of Experimental Medicine@jem.org · 10mo ago@lbernaleau.bsky.social et al @rebsamenlab.bsky.social identify ER-resident CCDC134 as an essential regulator of TLR responses that binds & stabilizes the TLR chaperone Gp96 rupress.org/jem/article/... From our #InnateImmunity collection: rupress.org/jem/collecti...
Full room at the start of the 2nd Immunobiology symposium on pattern recognition receptors! Looking forward to the great programme that we lined up for you together with @brozlab.bsky.social @martinon.bsky.social #ImmunoSky
📣 Reminder 📣 There is still time to apply for this #job #opportunity in the field of #metabolic #diseases at the Department of Biomedical Sciences @fbm-unil.bsky.social @unil.bsky.social 👇👇👇
@fbm-unil.bsky.social · last yr.📢 Applications open for a Tenure-track Assistant Professor towards Associate Professor in the field of #metabolic #diseases 📍 within the Department of Biomedical Sciences ❗ Apply before August 10th, 2025 More info 👉 wwwfbm.unil.ch/releve/appli... #joboffer @unil.bsky.social
Paper(s) alert from our RESOLUTE project – In a compilation of four papers in @molsystbiol.org we show how we were deciphering cellular logistics and present a comprehensive systematic blueprint of chemical transport pathways with #SoluteCarrier transporters
🚨 Abstract submission deadline: July 15th 2025🚨 Do not miss the opportunity to present your research: 10 selected short talks and an exciting poster session! Register and submit your abstract here: wp.unil.ch/immunobiolog...
Rebsamen Lab @UNIL@rebsamenlab.bsky.social · last yr.🚨Registrations are open🚨 Join us in Lausanne Switzerland October 1-2 for an exciting symposium on innate immunity with oustanding invited speakers, short talks selected from submitted abstracts and poster sessions. Attendance is limited to 150 participants!
Big congratulations to Cyrielle Hou (@dib-unil.bsky.social @fbm-unil.bsky.social) for receiving the Young Investigator Award at the 13th Meeting of the International Society of Systemic Autoinflammatory Diseases (ISSAID) in Paris! 🏆👏 And kudos to the organizers for a fantastic conference!
The whole DIB would like to congratulate Pascal Schneider for his Lifetime Achievement Award! More info: www.unil.ch/news/1749042...
We're looking forward to taking part in this meeting this October! JEM's Deputy Editor Gaia Trincucci (@gaiajexpmed.bsky.social) will be there – be sure to connect with Gaia to discuss your research and learn about publication 🔬💻✍️📄 #InnateImmunity #Immunobiology
Rebsamen Lab @UNIL@rebsamenlab.bsky.social · last yr.Interested in #InnateImmunity ? Register now to secure your spot — abstracts can be submitted later! More info: wp.unil.ch/immunobiolog... #ImmunoSky
🌿 Bravo aux 12 laboratoires certifiés LEAF @fbm-unil.bsky.social 👏 Arber Lab, Bagni Lab, Chatton Lab, Du Pasquier Lab, Jourdain Lab, LPA, M-Lab, Martinon Lab, Rebsamen Lab, Suter Lab, Thome Lab, Widmann Lab. ➡️ www.unil.ch/news/1747834... #LEAF #recherche #durable
Le programme LEAF reconduit pour une nouvelle année
12 Laboratoires ont reçu une certification LEAF (Laboratory Efficiency Assessment Framework) pour leur participation au programme de mai 2024 à mai 2025.
unil.ch
Interested in #InnateImmunity ? Register now to secure your spot — abstracts can be submitted later! More info: wp.unil.ch/immunobiolog... #ImmunoSky
Symposium immunobiology
wp.unil.ch
Rebsamen Lab @UNIL@rebsamenlab.bsky.social · last yr.🚨Registrations are open🚨 Join us in Lausanne Switzerland October 1-2 for an exciting symposium on innate immunity with oustanding invited speakers, short talks selected from submitted abstracts and poster sessions. Attendance is limited to 150 participants!
Research Highlight ✨|TASL has a key role in SLE Read the original articles: bit.ly/3XLPzUm and bit.ly/41FilqV 📖 @rebsamenlab.bsky.social @dib-unil.bsky.social
Nature Reviews Rheumatology@natrevrheum.nature.com · last yr.🚨Registrations are open🚨 Join us in Lausanne Switzerland October 1-2 for an exciting symposium on innate immunity with oustanding invited speakers, short talks selected from submitted abstracts and poster sessions. Attendance is limited to 150 participants!
Rebsamen Lab @UNIL@rebsamenlab.bsky.social · 2y agoWe are excited to announce the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors, Oct 1-2 2025, Lausanne, Switzerland. Registrations open March 1 - Attendance limited to 150 participants. More info: wp.unil.ch/immunobiolog... #ImmunoSky
What do Pablo Picasso and Charles Janeway have in common? Both were interested in patterns of life. Janeway was focused on pathogen associated molecular patterns (PAMPs) that are detected by our immune system. But what are these patterns he refers to?
Delighted to see our latest paper selected as “Research Highlight” by @natrevrheumatol.bsky.social ! Original study @naturecomms.bsky.social : rdcu.be/d7lK5 #lupus #innateimmunity #autoimmunity #ImmunoSky
Nature Reviews Rheumatology@natrevrheum.nature.com · last yr.🚨Registrations are open🚨 Join us in Lausanne Switzerland October 1-2 for an exciting symposium on innate immunity with oustanding invited speakers, short talks selected from submitted abstracts and poster sessions. Attendance is limited to 150 participants!
Rebsamen Lab @UNIL@rebsamenlab.bsky.social · 2y agoWe are excited to announce the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors, Oct 1-2 2025, Lausanne, Switzerland. Registrations open March 1 - Attendance limited to 150 participants. More info: wp.unil.ch/immunobiolog... #ImmunoSky
I'm really excited to join the University of Geneva as associate professor. I look forward to expanding our research program in systems immunology within the Department of Pathology and Immunology and contributing to advance the Faculty's data science capabilities! JOB OPPORTUNITY👇
#Macrophages literally eat and live of dead #bacteria, while live bacteria stimulate inflammation. 🦠 viability is sensed by an mTORC1 metabolic switch. Superb tour-de-force study @nature.com by the Garaude lab in Bordeaux, with help from @sanderlab.bsky.social www.nature.com/articles/s41...
Macrophages recycle phagocytosed bacteria to fuel immunometabolic responses - Nature
Phagocytosed bacteria can serve as an alternative nutrient source for macrophages, influencing their metabolic and immune responses through the recycling of microbial components, with the process regu...
nature.com
Chaque franc investi par @etatdevaud.bsky.social dans @unil.bsky.social en génère 4,7 dans le canton www.vd.ch/actualites/c...
Chaque franc investi par l’État de Vaud dans l’Université de Lausanne en génère 4,7 dans le canton | État de Vaud
L’activité de l’Université de Lausanne et sa présence dans le canton génèrent près de 9200 emplois et des retombées économiques de 1,73 milliard de francs. Une étude réalisée par…
vd.ch
No added sugar: CCDC134 stabilizes ER chaperone Gp96 for TLR biogenesis. Leslie Domínguez Cadena and Antje Blumenthal discuss new study from @lbernaleau.bsky.social et al. @@rebsamenlab.bsky.social (https://buff.ly/3ZrE70d) in Insights: https://buff.ly/4gwjt5N
💡 At a joint press conference, the #SNSF and its ERI partners called on the Federal Council to abandon the planned cuts to #education, #research and #innovation in the "relief package 27", as they would have far-reaching consequences for the #economy and society. ➡️ https://buff.ly/3CTR2AM
Check out the Insights piece from A Blumenthal & L Dominguez Cadena on our discovery of CCDC134’s role in Gp96 stability and TLR biogenesis. Many thanks to the authors for discussing our work broadly, integrating recent studies by Rohatgi and Locher/Kaelin labs, and highlighting key open questions.
No added sugar: CCDC134 stabilizes ER chaperone Gp96 for TLR biogenesis | Journal of Experimental Medicine | Rockefeller University Press
Bernaleau et al. show that CCDC134 located in the ER is required for TLR biogenesis by controlling the N-glycosylation, folding, and stabilization of the E
rupress.org
Journal of Experimental Medicine@jem.org · 2y agoInsights from Cadena & Blumenthal: Bernaleau et al. @rebsamenlab.bsky.social (https://buff.ly/3ZrE70d) show that CCDC134 located in the ER is required for TLR biogenesis by controlling the N-glycosylation, folding, and stabilization of the ER chaperone Gp96. https://buff.ly/4gwjt5N
This report investigates the effect of 21 variants in the hSLC39A8 gene experimentally on protein expression, localization, and uptake of metal ions, and computationally on dimerization stability RESOLUTE and REsolution the @supertifurgalab.bsky.social at CeMM https://buff.ly/4aHOzG3
Thrilled to see our recent paper on CCDC134 highlighted in @jem.org ! Grateful for the opportunity to contribute to this field and engage in meaningful discussions!
Journal of Experimental Medicine@jem.org · 2y agoInsights from Cadena & Blumenthal: Bernaleau et al. @rebsamenlab.bsky.social (https://buff.ly/3ZrE70d) show that CCDC134 located in the ER is required for TLR biogenesis by controlling the N-glycosylation, folding, and stabilization of the ER chaperone Gp96. https://buff.ly/4gwjt5N
