Review by the Mühlemann Lab with first author Wojciech Teodorowicz "Molecular determinants and therapeutic targeting of stop codon readthrough in eukaryotic translation" @jmolbiol.bsky.social nccr-rna-and-disease.ch/news/article... @omuhlemann-lab.bsky.social @unibe.ch
OMühlemann lab
@omuhlemann-lab.bsky.social
Excited about posttranscriptional gene regulation, in particular translation-coupled mRNA decay, and RNA Biology in general.
muehlemann.dcbp.unibe.ch/teaching.html Some insights into our lab (for prospective students). Thanks to Anupam, Franzi, and Helena for participating, and thanks to the UniBE MedLib production team!
Teaching
muehlemann.dcbp.unibe.ch
The credit goes to Wojciech! I hope the community eill find this review useful.
Review by the Mühlemann Lab with first author Wojciech Teodorowicz "Molecular determinants and therapeutic targeting of stop codon readthrough in eukaryotic translation" @jmolbiol.bsky.social nccr-rna-and-disease.ch/news/article... @omuhlemann-lab.bsky.social @unibe.ch
Our Summary of the (in my view) most exciting new insight into the mechanism of NMD of the past decade is now out at the RNA Journal @rnajournal.bsky.social doi.org/10.1261/rna....
NMD takes two PIN domains to tango
A monthly journal publishing high-quality, peer-reviewed research on all topics related to RNA and its metabolism in all organisms
doi.org
Congratulations Sebastian!
We would like to congratulate Sebastian Leidel ( @mcm5s2u.bsky.social ) on receiving the 2026 RNA Society Mid-Career Award! nccr-rna-and-disease.ch/news/article... @rnasociety.bsky.social @unibe.ch @snsf.ch
A hint for Swiss politicians: if you want Swiss science to remain internationally competitive, cutting the SNSF budget is the opposite of what you actually should be doing.
Ironically, at the same time, Swiss politicians are warning about China taking over the global lead in scientific discoveries and development of innovative technology.
While the Swiss government wants to cut the budget of the Swiss National Science Foundation by 5%, China has just announced a 10% budget increase for science and technology.
Happy to see this work published! Thanks to everyone who contributed 🙏
Publication by the Mühlemann & Chakrabarti Labs w/ 1st author Sofia Nasif "UPF1 shuttles between nucleus and cytoplasm independently of its RNA binding and ATPase activities” @rnajournal.bsky.social nccr-rna-and-disease.ch/news/article... @omuhlemann-lab.bsky.social @unibe.ch
Preprint by the Mühlemann & Ruepp labs w/ 1st author Alexander Hofer "Analysing the effect of full-length & C-terminally truncated progranulin on proliferation, colony formation, & migration in HepG2 & U87 cells" @biorxivpreprint.bsky.social buff.ly/0BOLAJb @omuhlemann-lab.bsky.social @unibe.ch
Lyse your favorite cell line with the dual centrifugation method: Detergent-free, in your buffer of choice, highly reproducible, and scalable.
Paper by the @karousislab.bsky.social & @omuhlemann-lab.bsky.social with first author Jana Ziegelmüller "Efficient cell-free translation from diverse human cell types" in the Journal of Biological Chemistry buff.ly/TwKbgRp @unibe.ch
⏰ Deadline alert! You only have until 1 June to submit your abstract for #EMBLProtein ⏰ Don't miss your chance to present your research ➡️ https://s.embl.org/trc24-01-bl 🗺️ EMBL Heidelberg and virtual 📅 3 – 7 September 2025
Preprint by the Mühlemann Lab ( @omuhlemann-lab.bsky.social ) with first author Sofia Nasif "UPF1 shuttles between nucleus and cytoplasm independently of its RNA binding and ATPase activities" @biorxivpreprint.bsky.social buff.ly/7McFICn @unibe.ch
Dictators and autocrats hate science because facts debunk their lies. That's the motivation behind Trump's massive attacks on U.S. research. www.republik.ch/2025/03/06/w...
Wie Trump die Wissenschaft attackiert
Zum Beispiel der Biologe Matthew Herron: der perfide Kampf der Trump-Regierung.
republik.ch
"Failed controls" can lead to scientific breakthroughs: our colleague André Schneider @schneian.bsky.social describes a few examples that should encourage every student not to dismiss an unexpected result. www.embopress.org/doi/full/10....
The controls that got out of control: How failed control experiments paved the way to transformative discoveries: EMBO reports: Vol 26, No 3
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
embopress.org
Petition an SRF für einen starken Wissenschaftsjournalismus www.openpetition.eu/ch/petition/...
Fakten statt Falschinformationen: Für einen starken Wissenschaftsjournalismus! - Online-Petition
Offener Brief aus der Wissenschaft an SRF Sehr geehrte Direktion der SRG, sehr geehrte Geschäftsleitung von SRF, sehr geehrte Medien- und Wissenschaftspolitiker:innen Mit grosser Besorgnis haben wir z...
openpetition.eu
Not to be missed!
We are pleased to announce registration for RNA 2025 - the 30th Annual Meeting of the RNA Society - is now open! www2.rnasociety.org This year’s meeting will be held at the beautiful Town and Country Resort & Convention Center in sunny San Diego, California, USA from May 27th - June 1st, 2025.
Congratulations to David Tollervey! He received this year's RNA Society Lifetime Achievement in Science Award. @rnasociety.bsky.social
Don't miss this week's #RNA highlights in Bern: The Swiss RNA Therapeutics Summit rnatx.ch on Thursday and the Annual Swiss RNA Workshop www.swissrnaws.dcbp.unibe.ch on Friday
Swiss RNA Therapeutics Summit – Uniting Leaders and Talents in RNA Therapeutics
rnatx.ch
New pre-print 📢:Cell-free translation from diverse human cell types: Fast, reproducible and scalable t.co/IAld0ocjDf @nickkouvelas.bsky.social @unibern.bsky.social #biorxiv #mRNA #Ribosome
Dear all, it was overdue to leave ex-Twitter and move to Bluesky. Happy to see that many of our old friends are here, too. We are attempting to connect to scientists interested in RNA biology and beyond. #translation #RNA #NMD