Please join us on October 15th at 11:45 for exciting talks from Prof. Dr. Christoph Schneider, who will talk about new tools to dissect the lung myeloid cell niche, and Dr. James King, who will present how airway inflammation triggers transition of lung eosinophils. See our flyer for details.
James King
@kingji.bsky.social
Post doc in the Arnold Lab, UZH. Former PhD of the Hepworth Lab, UoM. Fascinated in all things immunology.
Two post-doc positions available in our lab! It is a supportive environment and on which boosts careers! Historically, of our ~30 post-docs 27% have gone on to tenure-track positions, 27% did another post-doc, and 42% have gone on to positions in biotech or pharma.
HUGE news in Manchester. Excited to welcome @slg1717.bsky.social and her lab to the institute!
📣 We are delighted to announce world-leading immunologist Prof Sarah Gaffen as the incoming Director of the Lydia Becker Institute. Prof Gaffen succeeds founding Director @tracyh9494.bsky.social on Jan 1, 2027, as Tracy steps down after 8 years to focus on mentoring talent. 👉 tinyurl.com/3n4x5ave
🚨 We are hiring!! 🚨 2 postdoctoral research associate roles available in our lab - adverts now open, closing date 18/09/26. Details below - please spread the word far and wide!
Postdoctoral Research Associate in Immunology:Oxford Road
jobs.manchester.ac.uk
Delighted to share that I have been awarded a @cancerresearchinst.bsky.social (CRI) Irvington postdoctoral fellowship! This fellowship will fund the next 3 years of my research examining how aberrant glycosylation contributes to immune evasion in cancer 🥼🧫🦠
We’re excited to announce our next Swiss Myeloid League seminar taking place on July 14th at 16:30! Join us at UZH Irchel (Y15-G19) or online for talks by Prof. Dr. Isabelle Arnold and Dr. Laura Fisch (see flyer for details). The talks are followed by an apero. We hope to see many of you there!
✨Exited to share our brand new publication led by Kristina which provides a practical framework for eosinophil-focused single-cell RNA-sequencing analysis.✨ Check it out 👇 academic.oup.com/jleukbio/art...
Guidelines for single-cell RNA sequencing analysis of eosinophils
This study provides a practical framework for eosinophil-focused single-cell RNA-sequencing analysis that improves eosinophil recovery, annotation, and bio
academic.oup.com
Cytokine networks driving eosinophil functional heterogeneity www.mucosalimmunology.org/article/S193...
In-depth new review about eosinophil development and functions by the Arnold lab at UZH!
Do you wonder what eosinophils do outside of conventional type-2 immunity? Read our latest review that covers core cytokine networks that drive heterogeneous eosinophil function doi.org/10.1016/j.mu... www.sciencedirect.com/science/arti...
Excited to share this new review from James and Isabelle on cytokine-driven regulation of eosinophil development and functions. Check it out 👇
Do you wonder what eosinophils do outside of conventional type-2 immunity? Read our latest review that covers core cytokine networks that drive heterogeneous eosinophil function doi.org/10.1016/j.mu... www.sciencedirect.com/science/arti...
Do you wonder what eosinophils do outside of conventional type-2 immunity? Read our latest review that covers core cytokine networks that drive heterogeneous eosinophil function doi.org/10.1016/j.mu... www.sciencedirect.com/science/arti...
Cytokine networks driving eosinophil functional heterogeneity
Eosinophils have traditionally been viewed as terminally differentiated type 2 effector cells involved in anti-helminth immunity and allergic inflamma…
sciencedirect.com
@kimljacobson.bsky.social discusses Tachó-Piñot, Bashour, Filipska, et al’s new study (doi.org/10.1084/jem....) showing that mutated IgD+ B cell subsets populate epithelial areas of nasopharyngeal mucosa, ready to tackle a multitude of antigenic targets. rupress.org/jem/article/...
New study: @rosertp.bsky.social, Bashour, Filipska, et al (@victorgreiff.bsky.social & Cerutti labs, Uni Oslo & @researchmar.bsky.social) show IgD responses involve a heterogenous pop. of IgD class-switched memory #Bcells from epithelial areas of aerodigestive mucosa. rupress.org/jem/article-...
Thrilled to see our IgD work come out in @jem.org! We uncover how nasopharyngeal tonsils generate IgD responses via mutated IgD class-switched B cells, primed to recognise diverse environmental antigens — shedding light on mucosal immunity & tolerance. 👉 Have a look: doi.org/10.1084/jem....
IgD from atypical-like memory B cells and plasma cells targets commensal and environmental antigens
IgD responses involve a heterogeneous population of IgD class-switched memory B cells that inhabit epithelial areas of the aerodigestive mucosa and differe
rupress.org
Please share! Ever wondered how to establish and maintain wildlings – and why they matter? Our new paper “Game of microbes: a wildling ’s guide” is now out in Trends in Microbiology dlvr.it/TRl1Zs - Thread below with key previous work @cp-trendsmicrobiol.bsky.social @cellpress.bsky.social @FAU.de
Game of microbes: a wildling’s guide
Laboratory mice housed under specific pathogen-free conditions are the standard model in biomedical research. However, frequent germ-free rederivation and barrier housing restrict microbial exposure a...
dlvr.it
Please share! We hire PIs working in microbiome, metabolism, cancer, allergies, autoimmunity, neurological and infectious diseases. We offer SPF-, gnotobiotic- and wildling-models + generous lab space + top notch equip., e.g. SONY ID7000, 10X Xenium, MACSima. Contact: stephan.rosshart@uk-erlangen.de
Following up on the findings from our first article (wellcomeopenresearch.org/articles/10-...), here is the preprint of our study on neuroimmune alterations in school-aged children with perinatal HIV exposure #publicationalert #preprintalert #HIV #paediatrics
wellcomeopenresearch.org
Persistent neuroimmune alterations in children who are HIV-exposed but uninfected at age 6-7 years: Associations with language development in a South African birth cohort https://www.biorxiv.org/content/10.64898/2026.03.03.709328v1
New paper out from the lab, led by Maddy Hurry. We investigate how stroke leads to peripheral complications in the gut through dysregulation of IgA mediated host-commensal crosstalk. @lydiabeckeriii.bsky.social @diiirm.bsky.social www.sciencedirect.com/science/arti...
Cerebral ischaemic stroke results in altered mucosal antibody responses and host-commensal microbiota interactions
Stroke is a devastating neurological event with a high risk of mortality that results in long-term sequalae that extend beyond the central nervous sys…
sciencedirect.com
We had such a great time in #Montpellier at the #IES2025. Big congratulations to our awards receivers: Glenn for the best oral abstract talk and travel grant, @danielcrepaz.bsky.social for best abstract slam and @kingji.bsky.social for travel grant! #eosinophils
Really thrilled to have been awarded an @acmedsci.bsky.social Springboard Award! This new PI thing is definitely starting to feel real now! The #Springboard25 will help me to kickstart some cool work on innate-like T cells in skin and lungs at the @lydiabeckeriii.bsky.social! Exciting times ahead!