Thrilled to share that postdoc @megtriesscience.bsky.social was awarded a @cancerresearchinst.bsky.social Irvington Postdoctoral Fellowship! Her funded work is defining a role for glycans in colorectal cancer initiation. Learn more: www.cancerresearch.org/cri-funded-s... Congratulations, Megan! 🍾

Megan Priestley, PhD - Cancer Research Institute

Colorectal cancer is the second deadliest cancer worldwide, and rates are rising alarmingly among younger adults. Although immunotherapy has transformed treatment for some cancers, more than 90% of co...

cancerresearch.org

Delighted to share that I have been awarded a @cancerresearchinst.bsky.social (CRI) Irvington postdoctoral fellowship! This fellowship will fund the next 3 years of my research examining how aberrant glycosylation contributes to immune evasion in cancer 🥼🧫🦠

Five questions with Jessica Stark @jcstark.bsky.social go.nature.com/42sA99y

Five questions with Jessica Stark - Nature Biotechnology

A builder and problem solver at heart, she is developing technologies to understand and engineer the roles of cell-surface sugars, called glycans, in the immune system.

go.nature.com

One month left to submit abstracts! Deadline is 22nd March - don’t miss out 🤝

Megan Priestley@megtriesscience.bsky.social · 9mo ago

Happy new year Proteoglycans lovers! 🦠 We’re calling all early-career scientists diving into the dynamic world of Proteoglycans to register for the 2026 GRS on Proteoglycans – you won’t want to miss it! 🧪 www.grc.org/proteoglycan...

Happy new year Proteoglycans lovers! 🦠 We’re calling all early-career scientists diving into the dynamic world of Proteoglycans to register for the 2026 GRS on Proteoglycans – you won’t want to miss it! 🧪 www.grc.org/proteoglycan...

Congratulations @jcstark.bsky.social and the team, antibody-lectin chimeras (AbLecs), a new modality for cancer immune therapy, now published @natbiotech.nature.com. These bispecifics can block glyco-immune checkpoint receptor ligands directly at the immune synapse/activate immune effector functions

Nature Biotechnology@natbiotech.nature.com · 10mo ago

Antibody-lectin chimeras for glyco-immune checkpoint blockade - @jcstark.bsky.social @carolynbertozzi.bskyverified.social go.nature.com/4aRDpk8

Antibody-lectin chimeras for glyco-immune checkpoint blockade - @jcstark.bsky.social @carolynbertozzi.bskyverified.social go.nature.com/4aRDpk8

Antibody-lectin chimeras for glyco-immune checkpoint blockade - Nature Biotechnology

Cancer immunotherapy benefits from antibody-lectin chimeras that block glyco-immune checkpoints.

go.nature.com

Exciting to see the first bit of work from my postdoc out! Thanks to Jessica for letting me be a small part of this cool #glycotime project! Read more in her thread below 👇 Or in the research briefing I co-wrote with Jessica here! www.nature.com/articles/s41...

Targeting glycans for cancer immunotherapy - Nature Biotechnology

Antibody–lectin chimeras (AbLecs) are an immunotherapy modality designed to bind and block glycans that contribute to immune suppression in cancer. AbLecs enhance antitumor immune responses both in vi...

nature.com

Jessica Stark@jcstark.bsky.social · 10mo ago

Out now: We present antibody-lectin chimeras (AbLecs) as a molecular platform to target sugars, or glycans, for cancer immunotherapy. www.nature.com/articles/s41... www.nature.com/articles/s41... @mitkochinstitute.bsky.social @mitdeptofbe.bsky.social @mitcheme.bsky.social @stanford-chemh.bsky.social

🏆 Huge congratulations to our Director Professor Tracy Hussell @tracyh9494.bsky.social who has been awarded the Nature 2025 Lifetime Achievement Award for Mentoring in Science for her exceptional support of emerging scientists. #ImmunoSky @nature.com sites.manchester.ac.uk/lydia-becker...

Professor Tracy Hussell Receives Nature Lifetime Achievement Award for Mentoring in Science

Professor Tracy Hussell receives the 2025 Nature Lifetime Achievement Award for Mentoring in Science, recognising her outstanding support of early-career researchers.

sites.manchester.ac.uk

What a way to close the year!!! An amazing webinar dedicated on Glycobiology full of research highlights, advancements, new tools and inspiration!!!! Such a great group of people. Go follow them ⚡@megtriesscience.bsky.social @merrylabnotts.bsky.social @lornamilne.bsky.social @glycoluke.bsky.social

🔬Be sure not to miss our last seminar of the year! Featuring short talks by @megtriesscience.bsky.social and members of the Nottis GlycoAnalytics Hub, followed by keynote speaker @merrylabnotts.bsky.social with an exciting talk on glycosaminoglycan! 📅 December 9 ⏲️2pm (GMT), 3pm (CET), 9am (EST).

Really looking forward to speaking about my PhD work at this webinar with @merrylabnotts.bsky.social @themeshwork.bsky.social ! 🦠🎄

The Meshwork@themeshwork.bsky.social · 11mo ago

🔬 Glycobiology geeks — this one’s for you! “Beyond Proteins: Exploring the Hidden World of Glycans” With @merrylabnotts.bsky.social + @megtriesscience.bsky.social 📅 December 9 ⏲️ 2pm (GMT), 3pm (CET), 9am (EST) Don't miss out!! @amsocmatbio.bsky.social

New findings in #ScienceSignaling show that cells called leukocytes have a surface “coating” that can be modified during inflammatory conditions, such as #psoriasis, revealing how immune cells are recruited to sites of inflammation. https://scim.ag/4osBp5U

Leukocytes have a heparan sulfate glycocalyx that regulates recruitment during psoriasis-like skin inflammation

Leukocytes accumulate in the skin during psoriatic-like inflammation upon cleavage of surface heparan sulfate.

scim.ag

Congratulations to BLS Lecturer Dr Amy Saunders who has co-authored research featured on the front cover of this week's issue of #ScienceSignaling! Dr Saunders' research has updated our understanding of how glycans help immune cells move into skin in psoriasis. www.science.org/doi/10.1126/...

Leukocytes have a heparan sulfate glycocalyx that regulates recruitment during psoriasis-like skin inflammation

Leukocytes accumulate in the skin during psoriatic-like inflammation upon cleavage of surface heparan sulfate.

science.org

Leukocytes have a heparan sulfate glycocalyx that regulates recruitment during psoriasis-like skin inflammation | Science Signaling www.science.org/doi/10.1126/... 🧪

Leukocytes have a heparan sulfate glycocalyx that regulates recruitment during psoriasis-like skin inflammation

Leukocytes accumulate in the skin during psoriatic-like inflammation upon cleavage of surface heparan sulfate.

science.org

GAGs FTW! Wow #glycotime!! ⤵️🧪 🥳🥳 "Leukocyte recruitment is a key driver of inflammatory diseases, including psoriasis. Here, we found that leukocytes had the glycocalyx component heparan sulfate on their cell surface and that it was lost in response to psoriasis-like skin inflammation"

Waggoner Lab@labwaggoner.bsky.social · 12mo ago

Leukocytes accumulate in the skin during psoriatic-like inflammation upon cleavage of surface heparan sulfate www.science.org/doi/10.1126/... @megtriesscience.bsky.social @douglaspdyer.bsky.social

Don’t miss this week’s issue of #ScienceSignaling! New discoveries about an enigmatic, cancer-linked mutation could redefine understanding of the kinome, a study reveals how immune cells are recruited to inflammatory sites in psoriasis, and more. https://scim.ag/3LkFGtC

What a week! So pleased to now also see the peer reviewed version in Science Signaling of @megtriesscience.bsky.social PhD work joint with the Saunders lab, see her great thread for explanation below www.science.org/doi/10.1126/...

Leukocytes have a heparan sulfate glycocalyx that regulates recruitment during psoriasis-like skin inflammation

Leukocytes accumulate in the skin during psoriatic-like inflammation upon cleavage of surface heparan sulfate.

science.org

Megan Priestley@megtriesscience.bsky.social · 12mo ago

My PhD work is (finally) published in Science Signaling! And it made the cover! Here’s what we found 🧵⬇️ www.science.org/doi/10.1126/...

Leukocytes accumulate in the skin during psoriatic-like inflammation upon cleavage of surface heparan sulfate www.science.org/doi/10.1126/... @megtriesscience.bsky.social @douglaspdyer.bsky.social

Leukocytes have a heparan sulfate glycocalyx that regulates recruitment during psoriasis-like skin inflammation

Leukocytes accumulate in the skin during psoriatic-like inflammation upon cleavage of surface heparan sulfate.

science.org

👏 Congratulations to former Becker @wellcometrust.bsky.social ICD PhD student @megtriesscience.bsky.social on her first-author paper in Science Signaling!

Megan Priestley@megtriesscience.bsky.social · 12mo ago

My PhD work is (finally) published in Science Signaling! And it made the cover! Here’s what we found 🧵⬇️ www.science.org/doi/10.1126/...

Great to see this story in print! Congrats @megtriesscience.bsky.social @douglaspdyer.bsky.social and team! Looking forward to sharing Megan's first contributions as a postdoc in our lab at @mitdeptofbe.bsky.social @mitcheme.bsky.social @mitkochinstitute.bsky.social soon... 👀

Megan Priestley@megtriesscience.bsky.social · 12mo ago

My PhD work is (finally) published in Science Signaling! And it made the cover! Here’s what we found 🧵⬇️ www.science.org/doi/10.1126/...

Amazing work from @megtriesscience.bsky.social so proud of you and how this story has turned out!! @lydiabeckeriii.bsky.social @mcrcellmatrix.bsky.social

Megan Priestley@megtriesscience.bsky.social · 12mo ago

My PhD work is (finally) published in Science Signaling! And it made the cover! Here’s what we found 🧵⬇️ www.science.org/doi/10.1126/...

My PhD work is (finally) published in Science Signaling! And it made the cover! Here’s what we found 🧵⬇️ www.science.org/doi/10.1126/...

REGISTRATION FOR THE 2026 PROTEOGLYCANS GRS + GRC IS NOW OPEN! 🦠 (….and there’s a discount 😍) Join us next summer for the GRS on Proteoglycans! We’re so excited to welcome our early career researchers that we’re giving the first 20 sign-ups a bursary towards their travel 🧵⬇️

Great opportunity available in my PhD lab! An exciting project with a really fun and supportive team 🦠

Doug Dyer@douglaspdyer.bsky.social · last yr.

We have a new Postdoc position advertised as part of our recent long-term Wellcome funding to join an established Postdoc and technician. I’m so excited to explore the role of the glycocalyx in CNS-inflammation. So many tools and expertise to work with! www.jobs.manchester.ac.uk/Job/JobDetai...

My first presentation as a postdoc! 🎙️ Yesterday I attended the KendallSqBio postdoc symposium where it was a pleasure to discover the cool work going on in our area as well as share what I’ve been up to with my lab’s new story on glycans in cancer! 🦠

It was a pleasure to write this piece on HPV immunisation as part of our #CelebrateVaccines series 💙 Now more than ever, it is critical that we share evidence based resources on vaccination to help people make informed decisions about their health 🦠💉🌍

British Society for Immunology@britsocimm.bsky.social · 2y ago

Cervical cancer is the 4th most common cancer in women: bit.ly/4gDCdk5. Thanks to the HPV vaccine, that’s changing. Find out how it has transformed cervical cancer prevention in the first blog of our #CelebrateVaccines series: bit.ly/4hXQSXF

Slippery proteins in the brain’s blood vessels form a protective barrier that breaks down with age https://go.nature.com/3Xm6v3R

‘Slime’ keeps the brain safe ― and could guard against ageing

Nature - Slippery proteins in the brain’s blood vessels form a protective barrier that breaks down with age, studies in mice show.

go.nature.com

Well done Meg! So exited for what you will do in the next few years

Megan Priestley@megtriesscience.bsky.social · 2y ago

After a great few weeks settling into my new lab with @jcstark.bsky.social at the @mitkochinstitute.bsky.social , I’m thrilled to share I have been awarded a TBBCF postdoc fellowship! This award will fund the next 2 years of my research targeting glycans for the treatment of breast cancer 🦠