Interested in a faculty career in biomedical engineering #BME? Apply for the Rising Stars in Engineering in Health workshop for postdocs and PhD students interested in engineering, medicine & health: be.engineering.upenn.edu/home/rising-... Applications are open until July 31, 2026. Please share!
Jan Lammerding - Lab
@lammerdinglab.bsky.social
We study lamins and nuclear mechanobiology. Meinig School of Biomedical Engineering. Weill Institute for Cell and Molecular Biology. Cornell University. https://lammerding.wicmb.cornell.edu/
Two recent new publications from our laboratory, led by the amazing Jacob Odell and Maggie Elpers, respectively, shed new insights into the role of nuclear #lamins and nuclear #mechanobiology in two different contexts.
Attending #EESMechanobiology ? If so, be sure to find and chat with @djdavid.bsky.social (Daryl), one of our senior scientific editors. He'll be on site on Tuesday and Wednesday.
Enroute to #EESMechanobiology! proud to represent both @natcellbio.nature.com as senior editor and npj Biological Physics & Mechanics as advisory editor. Let's discuss your interesting work, science publishing, & more! Find me around &at the #MeetTheEditor lunch On Wed. Note, I'm only here Tues+Wed
Great start to the Cornell Mechanobiology Hub Symposium hosted by the @weillinstitute.bsky.social, with keynote speaker Amy Shyer and over 180 participants from more than 15 institutions. #Mechanobiology thrives in Ithaca and the region, including Syracuse, Rochester, Buffalo, and Binghamton.
First long term confocal imaging #Zeiss from the lab. Adipose-derived stem cells expressing LifeAct.
Interested in #Mechanobiology? Join us for the Mechanobiology Symposium, hosted by the new Cornell Mechanobiology Hub @weillinstitute.bsky.social in Ithaca, NY, this summer. More information at mechanobiology.wicmb.cornell.edu/events-progr... Deadline for abstract submission is April 15, 2026
Interested in the nuclear envelope? Do you reside in the US northeast (or are willing to pay a visit)? Don't miss this year's NENE (northeast nuclear envelope) - a trainee-led regional meeting that brings together scientists at all levels for a day of exciting talks and discussions. June 5th @ Yale
Deb Roy, Inoue et al. @jhu.edu introduce an #optogenetics tool to rapidly induce #microtubule acetylation in living cells and show that this triggers release of the RhoGEF GEF-H1 from #microtubules, thereby driving persistent directional cell migration. rupress.org/jcb/article/... #Cytoskeleton
Interested in a PhD in collective cell migration & mechanobiology? I'm looking to support a candidate applying for a fully funded UK/Home PhD. The project studies the biophysics of migrating cells, using force measurements & optogenetics, with collaborators in Japan. #mechanobiology #PhD eb4bm.org
Home - Engineering Biology For Biomedicine
Engineering Biology for Biomedicine A UKRI:BBSRC Centre for doctoral training Why EB4BM “ Our graduates bridge fundamental biological design principles with biomedical bottlenecks, delivering engineer...
eb4bm.org
Considering a graduate degree in biomedical engineering and wondering if a Master of Engineering degree is worth it? Join this virtual information session hosted by the Meinig School of Biomedical Engineering at Cornell University: www.duffield.cornell.edu/bme/meng/ MEng applications are still open!
Great summer research opportunity for undergraduate students interested in cardiovascular research at Cornell BME. Projects range from tissue engineering and cardiac device to disease models and spatial & single cell transcriptomics. Apply at: www.cnf.cornell.edu/education/re.... Please share.
New undergraduate summer research opportunities in cardiac research and biomedical engineering at the Cornell Meinig School of Biomedical Engineering, sponsored by the American Heart Association. Apply by Feb. 28 at www.cnf.cornell.edu/education/re.... Please share.
Cornell Cardiac Undergraduate Research Experience (CURE) Program | CNF
cnf.cornell.edu
Lamins A and C is required to anchor emerin at the nuclear envelope, and mutations in these proteins cause devastating diseases such as Emery-Dreifuss muscular dystrophy (EDMD). In work now available in #JBiolChem at www.jbc.org/article/S002..., we identify a novel lamin A/C-emerin binding site.
Very exciting work from @maggieutgaard.bsky.social in the Beach & Oakes labs pointing to a novel mechanoresponsive roles of septins in protecting the nucleus from mechanical stress. Enjoy the science, and the beautiful movies!
So excited to share the preprint with the bulk of my PhD work in the Beach @myosincity.bsky.social and Oakes @pwoakes.bsky.social Labs at Loyola University Chicago! We investigate the structure, recruitment, and function of septin networks around the nucleus. A thread: doi.org/10.64898/202...
Negin Majedi delivering a fantastic kick-off presentation on the #mechanobiology of cancer immune engineering as part of the new #MechanobiologyHub seminar series hosted by the @weillinstitute.bsky.social at Cornell University.
Attending the ASCB/EMBO Cell Bio #cellbio2025 in Philadelphia? Check out the posters from our lab on nuclear mechanobiology, lamins, and mechanotransduction today and on Tuesday. I will be there too and look forward to catching up!
Motivational video for #MigrationMovieMonday. A persistent 4T1 breast cancer cell squeezing itself through a tight constriction despite undergoing repetitive nuclear envelope rupture. Credit: Kristen Nedza @weillinstitute.bsky.social
Thanks to @katemiro.bsky.social , Megan King, Verena Ruprecht & @lammerdinglab.bsky.social for organising the very first meeting on the “Mechanobiology of the Nucleus” #MBNSRC @faseborg.bsky.social and for the invitation to present our discoveries. The conference was fantastic!
End of an incredible meeting — Mechanobiology of the Cell Nucleus #MBNSRC. So proud of my PhD student @leamayeur.bsky.social for winning the Best Early Career Researcher Presentation Award! 🏆👏
It’s been a pleasure working with @apdaria.bsky.social, Julie Heffler, and the Prosser Lab on this study, supported by the Leducq Foundation and the National Institutes of Health (NIH). This research is one step to get us closer to an effective treatment for cardiac #laminopathies and #LMNA-DCM.
It is finally out! Updated with exciting in-vivo microtubule disruption results to protect Lmna deficient nuclei from damage. My final postdoc project with Prosser Lab and a great collaboration with @lammerdinglab.bsky.social, Shenoy Lab, and Jain lab.
How do LMNA mutations cause dilated cardiomyopathy (DCM) and other #laminopathies? In our latest preprint (doi.org/10.1101/2024...), led by the amazing Noam Zuela-Sopilniak and Julien Morival, we show that cardiomyocyte-specific lamin A/C depletion causes severe DCM, consistent with other studies.
Odell, J et al. (@lammerdinglab.bsky.social lab) A-type lamins anchor emerin at the inner nuclear membrane via two independent binding sites. bioRxiv posted 2 September 2025 doi:10.1101/2025.09.01.673543. www.biorxiv.org/content/10.1...
A-type lamins anchor emerin at the inner nuclear membrane via two independent binding sites
Lamins form a dense meshwork at the inner surface of the inner nuclear membrane (INM), where they interact with other nuclear envelope proteins such as emerin. Emerin is an integral membrane protein t...
biorxiv.org
Final call to register and submit abstracts for the @faseborg.bsky.social conference on the Mechanobiology of the Cell Nucleus (#MBNSRC) to be considered for platform presentations. The conference takes place in Melbourne, FL, Oct. 26-30, 2025. See more info at: events.faseb.org/event/Mechan...
Spread the word - we at @stanford-chemh.bsky.social are searching to fill a new junior faculty at the interface of molecular and computational science. See link below!
Open faculty position! We're seeking applicants for a tenure-track faculty position at the junior level (Assistant or untenured Associate Professor) with research programs that exist at the interface between molecular science and computation. Apply here: stanford.io/45MF3Qa
FOMO no more: NOMO and Calmin extend #mechanobiology to the ER. Julie Heffler and Jan Lammerding @LammerdingLab.bsky.social discuss recent studies from the @schliekerlab.bsky.social (doi.org/10.1083/jcb....) & @hennelab.bsky.social (doi.org/10.1016/j.ce...), in Spotlight: rupress.org/jcb/article/...
Interested in #mechanobiology of the cell nucleus? The submission deadline for the first ever FASEB Science Research Conference on the Mechanobiology of the Nucleus is August 31, 2025. Submit your abstract to be considered for a platform presentation. #MBNSRC events.faseb.org/event/Mechan...
Last chance to register and submit an abstract to be considered for a platform presentation. If you are interested in nuclear #mechano Ta
Looking forward to meeting "old" & new friends at the FASEB Science Research Conference on the Mechanobiology of the Nucleus #MBNSRC. Submit your abstract by Aug, 31!
Heffler and @LammerdingLab.bsky.social discuss recent studies from the @schliekerlab.bsky.social (doi.org/10.1083/jcb....) and @hennelab.bsky.social (doi.org/10.1016/j.ce...) that identify two proteins serving as crucial mechanical elements in the endoplasmic reticulum. rupress.org/jcb/article/...
Please submit your abstracts by August 31st to be considered for a platform presentation! We look forward to an exciting and stimulating meeting! Please share!
A Nuclear Mechanobiology meeting is a dream come true!!! Please join us!
Happy #FluorescenceFriday! Our #CellLineOfTheWeek is MLC-2a - illuminating sarcomeric thick filaments! 💪🧫 Our high-quality stem cell lines & plasmids are available for just the cost of shipping to reduce the barriers to discovery. 📦 Dist. by @coriellinstitute.bsky.social & @addgene.bsky.social.
The Anne West lab at Duke is hiring a postdoc to work on nuclear cell biology in neurogenesis. Please help me spread the word! Applications to west@neuro.duke.edu.