Great collaboration with @bastinlab.bsky.social to image node cilia and assess in parallel ccdc40 function in mouse and trypanosome cilia.

Philippe Bastin's Lab@bastinlab.bsky.social · 2mo ago

There is more than cilia beating in the establishment of left-right symmetry! Proud to have contributed to this beautiful study by Amaia Ochandorena Saa @meilhacsigolene.bsky.social where Thierry Blisnick imaged mouse node by SEM doi/10.1126/sciadv.adx6486 @pasteur.fr @institutimagine.bsky.social

New publication, new insights into left-right patterning in mice. We revisit the role of the node, from a left-right organiser to one biasing factor among others. www.science.org/doi/10.1126/...

Wnt and Nodal asymmetries stratify mouse laterality phenotypes in the absence of node flow

Asymmetry establishment without node flow reveals an alternative symmetry-breaking event in the mesoderm involving WNT signaling.

science.org

Sigolène Meilhac@meilhacsigolene.bsky.social · 8mo ago

New publication : is left-right symmetry-breaking in mice in the node ?

Sigolène Meilhac @meilhacsigolene.bsky.social will be speaking on "Congenital structural heart defects" at our Journal Meeting in the UK this September #HumanDev26 Register to attend: biologists.com/meetings/dev... Abstract deadline: 12 June 2026

*** GRC Developmental Biology 2027 - Jan 17-22 @ Renaissance Tuscany Il Ciocco Resort *** Join us for a fabulous 2027 Gordon Conference on all things #devbio & the trainee-led GRS! More info on registration, abstract submission, et al., here: www.grc.org/developmenta... #GRCDevBio2027 🧬🐭🐟🪰🌱❤️

Happy team photographed by Yann Arthus-Bertrand. Do you see clues of our research focus ?

New publication : is left-right symmetry-breaking in mice in the node ?

bioRxiv Developmental Biology@biorxiv-devbio.bsky.social · 9mo ago

Wnt and Nodal asymmetries stratify mouse laterality phenotypes in the absence of node flow https://www.biorxiv.org/content/10.64898/2025.12.21.695689v1

There a is a joint call between @pasteur.fr and @cnrsbiologie.bsky.social for a mid career group leader position in AI and genomics (or molecular biology). Don't hesistate to spread the word if you know anyone relevant. research.pasteur.fr/en/call/mid-...

Mid-career Group Leader position in AI in genomics at Institut Pasteur, Paris - Research

Institut Pasteur and the CNRS are launching a call for a mid-career group leader position in AI in genomics. We are looking for an experienced researcher (typically with > 8 years of research experien...

research.pasteur.fr

New publication : Despite being a core member of the PCP pathway, Vangl2 can play roles unrelated to planar polarity. This is the case during mouse heart morphogenesis.

bioRxiv Developmental Biology@biorxiv-devbio.bsky.social · last yr.

VANGL2 shapes the mouse heart tube from adjacent epithelia and without planar polarity https://www.biorxiv.org/content/10.1101/2025.09.05.674213v1

Congratulations Dr Amaia Ochandorena-Saa for a beautiful PhD, defended in front of Hiroshi Hamada, @bakkerslab.bsky.social, Alice Meunier and Jeanne Amiel

New publication | Science Advances www.science.org/doi/10.1126/...

Plasticity of ventricle position after heart looping in heterotaxy with right isomerism

The left/right position of ventricles needs to be maintained after heart looping, an unexpected step affected in heterotaxy.

science.org

New article of the lab on Notch3, not only involved in vascular or neural defects, but also in heart defects and laterality defects.

PLOS Biology@plosbiology.org · last yr.

Creating an asymmetric heart: @tbonnely.bsky.social @audreydsg.bsky.social @meilhacsigolene.bsky.social &co identify Notch3 as a novel asymmetric factor in lateral plate mesoderm that acts as a genetic modifier of NODAL to regulate #heart #morphogenesis @plosbiology.org 🧪 plos.io/42q6H4L

🧬 Join Institut Imagine as a Junior Group Leader! - Junior Group Leader in Systems and Computational Biology - Junior Group Leader in RNA Biology and Epigenomics - Junior Group Leader in Artificial Intelligence for Genetics, Biology & Medicine To submit your application : lnkd.in/enm-U2tH

The Weinstein Committee is soliciting nominations for the 2025 Markwald Award. If you have a scientist you'd like to nominate send it to mpatterson@mcw.edu by February 7th!

Join us for the 2025 Weinstein Cardiovascular Development and Regeneration Conference in Milwaukee, May 14-16! Registration and abstract submission are now open!!! Please share, retweet, and distribute! #WeinsteinCVD2025 REGISTER TODAY HERE childrenswi.org/weinstein

We are opening a call for applications 2025 – Creation of new junior research groups at the Institut Pasteur in Paris @pasteur.fr all details on our web site : research.pasteur.fr/en/call/call...

Abstract submission is now open for the 2025 Weinstein Cardiovascular Development and Regeneration Conference at childrenswi.org/weinstein. The conference will be held in Milwaukee, May 14-16! Please share, retweet and distribute ❣️❣️❣️#WeinsteinCVD2025

Yes! We are hiring! Looking for highly motivated people to make good use of our #ERC_SyG money 💶! The project is super cool, and the people are the best!! There are plenty of opportunities for international collaborations, too! Please help us spread the word!

Yaara Tevet@yaaratevet.bsky.social · 2y ago

Karina Yaniv Lab at the Weizmann Institute is seeking PhD students and postdoctoral researchers. Come work with us!

We hire ! Open #postdoc position to study the emergence of heart asymmetry in Paris ! #devbio

For the dev bio crowd : there is a call for junior group leader at Institut Pasteur in Paris and one of the axis covered is related to development. Come and join us in this exciting place and become one of our colleague @devstempasteur.bsky.social Please RT !! research.pasteur.fr/fr/call/call...

🚨🚨🚨 Not one, but 3 calls for junior group leaders opening at Imagine!!! [please share] - Systems and computational biology - RNA biology and epigenomics - AI for genetics, biology and medicine Come and join us! www.nature.com/naturecareer...