Paula Navarro
@navarropaula.bsky.social
Cryo-electron tomography all the time. #teamtomo Assistant Professor at DMF-UNIL,Switzerland https://wp.unil.ch/navarrolab/
PLEASE SHARE! New job openings in my lab @zmbp-tuebingen.bsky.social. We have a broad interest into the mechanistic basis of how molecular complexes are rewired during cellular development in plants and during invasion by pathogens. 🌱🍄🔬 See details below 👇 #PlantSciJobs
The final version of @florentwaltz.bsky.social's Chlamy chlororibosome "hat" is now online at @natplants.nature.com 🌾 📜 nature.com/articles/s41477-026-02361-1 🧪🔬 #TeamTomo The charge complementarity in the arm domain is striking. Blue & red proteins wrapped around each other, like a barber pole💈
Florent Waltz@florentwaltz.bsky.social · 6mo agoLong in the making, but happy to present the Chlamydomonas chlororibosome! Cryo-ET🔬reveals a large new domain on the small subunit, built from multiple extensions in conserved ribosomal proteins. bioRxiv 📖: shorturl.at/q44tG This suggests greater chlororibosome diversity than expected! 1/n 🧵
cxtoolshed.rbvi.ucsf.edu/apps/chimera... Available through the toolshed now! Thanks to the chimera team for reviewing this one very quickly.
ChimeraX Toolshed - MorphometricsX
Resource for Biocomputing, Visualization amd Informatics (RBVI), and its precursor, the Computer Graphics Laboratory (CGL), develops cutting-edge interactive software tools and advanced web-based comp...
cxtoolshed.rbvi.ucsf.edu
Ben Barad@baradlab.com · last mo.My personal summer of code continues with another ChimeraX plugin - this time, MorphometricsX! Load quantified meshes from morphometrics (or pycurv) in ChimeraX with color-by-quantification and display alongside tomos and particles. Coming to the toolshed soon! #teamtomo github.com/baradlab/mor...
Out Now! The penicillin-binding protein PBP1b fortifies the Escherichia coli division site against osmotic rupture #MicroSky
The penicillin-binding protein PBP1b fortifies the Escherichia coli division site against osmotic rupture
Nature Microbiology, Published online: 03 July 2026; doi:10.1038/s41564-026-02403-6A specific isoform of PBP1b functions independently of the activator protein, LpoB, to drive generation of a wedge-like peptidoglycan structure that strengthens the division site in Escherichia coli.
go.nature.com
🔬 Rencontre avec @navarropaula.bsky.social, pour qui les secrets du vivant se cachent à l’échelle atomique. Pour explorer cet univers minuscule, la biologiste s’appuie sur la #cryo-microscopie #électronique. Lire la suite 👉 www.unil.ch/news/fr/1783...
Lausanne, Terre promise de la cryo-microscopie électronique
Pour Paula Navarro, les secrets du vivant se cachent à l’échelle atomique. Pour explorer cet univers minuscule, la biologiste s’appuie sur la cryo-microscopie électronique. Et s’il y a un endroit où p...
unil.ch
Great collab and awesome teams! @avettiger.bsky.social Tom Bernhardt @harvardmed.bsky.social
Andrea Vettiger@avettiger.bsky.social · last mo.Excited to see our story published in @natmicrobiol.nature.com today! It’s been a long journey. We answered a major outstanding question: why does E. coli encode two aPBPs, yet only one plays a critical role in ensuring reliable PG fortification during cell division?
🚨 New in @natmicrobiol.nature.com! We reveal how the antibiotic target PBP1b fortifies the E.coli division site against osmotic rupture. Proud this was completed in our independent labs @dmf-unil.bsky.social, with @avettiger.bsky.social. Congratulations to all authors! 🦠❄️🔬 #teamtomo bit.ly/3SCbOg1 👇
The penicillin-binding protein PBP1b fortifies the Escherichia coli division site against osmotic rupture - Nature Microbiology
A specific isoform of PBP1b functions independently of the activator protein, LpoB, to drive generation of a wedge-like peptidoglycan structure that strengthens the division site in Escherichia coli.
doi.org
Interested in synthetic biology & microbiomes? 🧬🧫 We are recruiting a PhD student to develop biosensors to study microbe–microbe & microbe–host interactions. In beautiful Lausanne, Switzerland🏔️⛵ @dmf-unil.bsky.social @fbm-unil.bsky.social Apply by 24.05.2026 👇 shorturl.at/6X7M4 Boosts appreciated!
Career Opportunities: PhD position in microbial synthetic biology (22753)
shorturl.at
I have a PhD student and a post-doc position available in my lab to work on plant photobiology. Please use the links below to postulate. Please RT, many thanks career5.successfactors.eu/career?caree... career5.successfactors.eu/career?caree...
#ProtistsOnSky no 'swimming' by 𝘝𝘢𝘮𝘱𝘺𝘳𝘦𝘭𝘭𝘢, definitively no 'staying still'. just a relaxed walk towards the lunch...
eLife@elife.bsky.social · 6mo agoDo microbes get more food by swimming or staying still? Turns out both work, and cilia help them pull in nutrients no matter the strategy. buff.ly/vK3GmK5
The @dmf-unil.bsky.social is supporting the application of a candidate for the SNSF/ERC Starting Grant (deadline 5th of May). Reach out to me if you are interested. We are collecting CV’s until the 8th of Feb. We can offer a stimulating scientific environment and help with the application/interview.
🚨📣Looking for SNSF/ERC Starting Grant host? @dmf-unil.bsky.social offers space, mentoring & admin support! Deadlines: SNSF 5 May, ERC ~Oct. Please, send us CV + brief research stmt by 8 Feb → reach out!!!🚀
✨Opportunity to join the 🦁🦠 Predatory Bacteria lab! My lab will move to University of Bern (CH) in April 2026 based on my #ERCStG. Therefore, we are looking for: -a PhD student (shorturl.at/mt0LR) -a 50% Technical Assistant/Lab manager (shorturl.at/0IIKe) 🙏Thanks for sharing. #MicroSky
Thrilled to share that the final piece of my PhD work is now on bioRxiv! biorxiv.org/content/10.1... With support from @nvidia and the @NSF, we used AlphaFold to screen 1.6M+ protein pairs, revealing thousands of potential novel PPIs. All data can be viewed at predictomes.org/hp
Proteome-wide in silico screening for human protein-protein interactions
Protein-protein interactions (PPIs) drive virtually all biological processes, yet most PPIs have not been identified and even more remain structurally unresolved. We developed a two-step computational...
biorxiv.org
And that’s a wrap on the Great Wall Symposium 2025! Roll on 2027, venue to be confirmed shortly …
We are hiring a Postdoc in membrane protein cryo-EM at the University of Georgia. Looking for candidates with expertise in membrane protein purification and biochemistry. Fully funded for up to 5 years. Join us in Athens, GA. Apply: camilo.perez@uga.edu
So happy to have contributed to this beautiful study led by PetrPelech! A combined theory–experiment effort based on our in situ cryo-ET data, revealing how stress-mediated growth shapes E. coli division site morphogenesis. #teamtomo 🌐 🦠🔬❄️🐎 👉📄 doi.org/10.1073/pnas...
Stress-mediated growth determines Escherichia coli division site morphogenesis | PNAS
In order to proliferate, bacteria must remodel their cell wall at the division site. The division process is driven by the enzymatic activity of pe...
doi.org
🚨New preprint!🚨 #teamtomo We expanded Surface Morphometrics to quantify membrane thickness from cryo-ET—revealing local variation across organelles. Led by the lab’s first grad student, @mmedina300kv.bsky.social (defending Monday! 🍾) w/ @attychang.bsky.social @hamid13r.bsky.social & @tomo.science
bioRxivpreprint@biorxivpreprint.bsky.social · last yr.Surface morphometrics reveals local membrane thickness variation in organellar subcompartments https://www.biorxiv.org/content/10.1101/2025.04.30.651574v1
We are looking for a postdoctoral fellow to join us to explore telomerase regulation by histones. Please get in touch if this may interest you.
MRC Laboratory of Molecular Biology@mrclmb.ac.uk · last yr.Excellent opportunity available for a motivated #postdoc to join @kellythd-nguyen.bsky.social’s group investigating the roles of histones in regulating telomerase using a multi-disciplinary approach. More details: www.nature.com/naturecareer... Apply by 04 MAY #PostdocJobs #ScienceJobs
Join the Blokesch lab (@EPFL) as a postdoc in Molecular Microbiology 🤩 Study Vibrio cholerae defense systems (phage/plasmid) in a dynamic, collaborative environment in Lausanne close to Lake Geneva in 🇨🇭! Please visit my lab's webpage for details about the position and how to formally apply.
After years parked at a Polara, I’m excited to share that my PhD work is finally out! We figured out why imaging at liquid helium temperatures wasn’t working—and how to fix it. 🔗 www.pnas.org/doi/10.1073/...
Reducing the effects of radiation damage in cryo-EM using liquid helium temperatures | PNAS
The physical limit in determining the atomic structure of biological molecules is radiation damage. In electron cryomicroscopy, there have been num...
pnas.org
Parmi les nouveaux #subsides de #recherche financés par le @snf-fns-ch.bsky.social 2️⃣3️⃣ projets de la #FBM (UNIL-CHUV-Unisanté) ont été retenus. Découvrez les nouvelles et nouveaux #récipiendaires ➡ www.unil.ch/news/1744125... 👏 Félicitations 👏 @unil.bsky.social #chuv #unisanté
Subsides de recherche financés par le FNS: nouvelles et nouveaux récipiendaires UNIL-CHUV-Unisanté
Parmi les nouveaux subsides de recherche financés par le FNS, 23 projets de la FBM (UNIL-CHUV-Unisanté) ont été retenus.
unil.ch
Our work on HIV-1 matrix, led by James Stacey and @dhrebik.bsky.social, is in this week's @nature.com. Extended explanatory video from @margotriggi.bsky.social. www.nature.com/articles/s41...
The aPBP-type cell wall synthase PBP1b plays a specialized role in fortifying the Escherichia coli division site against osmotic rupture www.biorxiv.org/content/10.1101/2025.04.02.646830v1 #cryoEM
🚨👉 Please check our recent work on bacterial cell division. In situ Cryo-ET reveals the cellular function of the penicillin binding protein 1b supported by AFM, live-cell imaging, in silico AlphaFold proteome screen and TIRFM. Hope you enjoy the read! #teamtomo #cryo-ET ❄️🔬🐎 big thanks to the team!
bioRxivpreprint@biorxivpreprint.bsky.social · last yr.The aPBP-type cell wall synthase PBP1b plays a specialized role in fortifying the Escherichia coli division site against osmotic rupture https://www.biorxiv.org/content/10.1101/2025.04.02.646830v1
Double the grants, double the money, double the impact! Huge thanks to our amazing teams -proof that scientific power couples thrive in inclusive, diverse and open-minded institutions. And the real winner? Science, of course!🏆🔬Grateful beyond words! ❄️🐎 @dmf-unil.bsky.social @snsf-ch.bsky.social
Asgard archaea have actin - but what about microtubules? Where do they come from? 🧐 Our new paper www.cell.com/cell/fulltex... by @xujwet.bsky.social & @florianwollweber.bsky.social, in collaboration with the Schleper & Wieczorek labs, describes tiny Asgard microtubules! #TeamTomo #ArchaeaSky 1/6
WE GOT THE COVER!!!
Science Magazine@science.org · last yr.In a new Science study, cryo–electron tomography captures the in-cell architecture of the mitochondrial respiratory chain, illuminating how the coordinated action of molecular machines drives life’s fundamental energy conversion. Learn more in this week's issue: scim.ag/3FA3Ygq
Hello bluesky community! Happy to be finally here ;)🐎