Lovely to celebrate with @kellythd-nguyen.bsky.social earlier this month on her Lister Prize 2025. Prize lecture, award presentation, great vibes. Our congratulations - and our thanks to such welcoming and supportive colleagues 🫶 Images with permission, @mrclmb.ac.uk

Kaitlyn continues to break barriers with her innovations for using LEA proteins to solve another major cryo-EM sample prep issue! This work should be of great interest to friends who are struggling with particle orientation bias. Another funtastic Lim X Grant collaboration! @uwbiochem.bsky.social

Kaitlyn Abe@kaitlynabe.bsky.social · 3w ago

1/5: Our latest preprint is out! We show that LEA proteins can diversify particle orientations in cryo-EM, helping to overcome preferred orientation at the air-water interface (AWI). www.biorxiv.org/cgi/content/... with @cijilim.bsky.social and Tim Grant #CryoEM #LEAproteins

📢 Calling early career biomedical researchers across the UK and Ireland. Wanted 🫵 Wow-factor proposals from stellar ECRs based in Ireland for #ListerPrize2027. Fellows, HoDs, research professionals, managers. Support the initiative. And repost 🙏 👉 lister-institute.org.uk/news/backing...

Incredibly proud of Messi Haile @mehsehret.bsky.social, a founding member of the Ho Lab, for her beautiful work uncovering the inner workings of a central piece of the malaria parasite invasion machinery: the malarial moving junction, out today in @cellpress.bsky.social! tinyurl.com/4p3md2eb 🦠❄️🔬

Honored to be elected to EMBO,together with Manu, Julian and ex-benchmate @wojtekgalej.bsky.social. I’m grateful to all past and present Iab members for their amazing work and support from colleagues, mentors and family over the years.

MRC Laboratory of Molecular Biology@mrclmb.ac.uk · last mo.

Congratulations to LMB Group Leaders Emmanuel Derivery, Kelly Nguyen and Julian Sale, who have all been elected members of @EMBO.org! Read more about their research at the LMB here: mrclmb.ac.uk/news-events/... #LMBNews @deriverylab.bsky.social @kellythd-nguyen.bsky.social @juliansalelab.bsky.social

Honoured and delighted to be elected as an EMBO Member. Many thanks to my group and to everyone who has supported me throughout the years. I am deeply grateful for this recognition.

EMBO@embo.org · last mo.

Welcome and congratulations to the 60 new members and 11 associate members who have been elected to the EMBO Membership! They join a community of more than 2,200 leading scientists. 🧪 https://www.embo.org/press-releases/seventy-one-leading-scientists-elected-to-the-embo-membership/ #EMBOMembers2026

Congratulations Caitie! Excited about future work from the McCafferty lab!

Caitie McCafferty@computingcaitie.bsky.social · last mo.

Happy to finally share that I will be starting my independent group at the @fmiscience.bsky.social in Feb 2027 in a vibrant new environment. We will use integrative in situ structural cell biology methods to investigate ciliary structure and dynamics in several model (and non-model 👀) systems!!

Two new preprints featuring work from @ryanymuller.bsky.social on PABPC biology! With important contributions from @eugenevalkov.bsky.social, Tanner Myers, and @kxwang.bsky.social

The molecular determinants of PABPC-mediated deadenylation rate

Deadenylation, the enzymatic shortening of the poly(A) tail, is typically the first committed step of mRNA decay. Deadenylation rates span nearly a 1000-fold range between transcripts and are governed...

biorxiv.org

New paper! How do RNAs "know" where to go inside a cell? We dug into the sequence elements that route RNAs to the right place. It turns out that, in mammals, they're surprisingly massive (>200 nt), multipartite, and wonderfully complicated. 🧵

Sub-cellular chemical mapping using correlated cryogenic electron and mass spectrometry imaging online @natmethods.nature.com, led by Hannah Ochner, collaboration with @catfranco.bsky.social and @kiranrpatil.bsky.social labs doi.org/10.1038/s415...

Earlier this week I posted an example of a fake western blot provided by ThermoFisher to demonstrate the validity of a p53 antibody. I considered it an amusing curiosity. In fact Thermo Fisher Scientific has systematically manipulated antibody validation data!

One, perhaps two, of our postdocs are moving on to faculty positions this year (more news soon!). While they're truly irreplaceable, it does mean that we have openings for new members to join our team studying #cilia. If interested, please apply: academicpositions.harvard.edu/postings/15526

Applications and prospects of cryo-electron tomography in drug discovery and understanding disease Review article by @camilaclemente.bsky.social in our lab www.sciencedirect.com/science/arti...

Applications and prospects of cryo-electron tomography in drug discovery and understanding disease

Cryo-electron tomography (cryo-ET) is emerging as a transformative tool for structural biology. Unlike methods based on purified molecules, cryo-ET en…

sciencedirect.com

Wow, cool story! Congratulations Ahmad and everyone involved!

Ahmad Jomaa@jomaalab.bsky.social · 3mo ago

Excited to share our work uncovering SNOR, a ribosome-associated factor that promotes translation restart after dormancy published in Nature!! This was, as usual, a wonderful collaborative effort between our group and the Mattei Lab @simonemattei.bsky.social @embl.org www.nature.com/articles/s41...

The Farnung Lab is looking for postdoctoral researchers interested in understanding mechanisms at the intersection of chromatin, transcription, and replication. Find out more here: www.farnunglab.com

Interested in molecular motors? Don’t miss this wonderful symposium in Salamanca on "The Structure and Workings of Molecular Machines" with an outstanding lineup of speakers. 📍 Salamanca, Spain 📅 Monday, June 22, 2026 🎟️ Attendance is free, but registration is required 👇👇👇

Oxygen gradients reshape cross-feeding through emergent spatial organization of gut commensal bacteria www.biorxiv.org/content/10.6... Use of isotope labels and cryo-CLEM-FIB-SIMS to study microbial communities by Hannah Ochner. Collaboration with @kiranrpatil.bsky.social @jmghigolab.bsky.social

Thrilled to see this work published. Thanks to helpful reviewer suggestions, there are some exciting new insights that were not in the preprint (particularly in Figure 4). www.nature.com/articles/s41...

MRC Laboratory of Molecular Biology@mrclmb.ac.uk · 3mo ago

The hidden rules behind mRNA transport. A collaborative study between @simonbullock11.bsky.social & @carter-lab.bsky.social’s groups has found a structural code that explains how cells selectively transport mRNAs. Read more: mrclmb.ac.uk/news-events/... #LMBNews @cellbiol-mrclmb.bsky.social 🧪

Our story on RNA recognition by Egl-BicD is now published! Also delighted to share the accompanying News & Views article by Florence Besse and Andres Ramos, which beautifully highlights the work. Paper: www.nature.com/articles/s41... News & Views: www.nature.com/articles/s41...

MRC Laboratory of Molecular Biology@mrclmb.ac.uk · 3mo ago

The hidden rules behind mRNA transport. A collaborative study between @simonbullock11.bsky.social & @carter-lab.bsky.social’s groups has found a structural code that explains how cells selectively transport mRNAs. Read more: mrclmb.ac.uk/news-events/... #LMBNews @cellbiol-mrclmb.bsky.social 🧪

Come and work with us on #cryoEM of alpha-synuclein amyloid filaments from #Parkinsons disease! 🥳 fa-evzn-saasfaukgovprod1.fa.ocs.oraclecloud.com/hcmUI/Candid...

Postdoctoral Scientist | Neurobiology | Dr Michel Goedert | LMB 2253

£42,694 per annum | Fixed-term for 3 years | Full-time | Closing date: 17 May 2026

fa-evzn-saasfaukgovprod1.fa.ocs.oraclecloud.com

New preprint from the lab, looking at how multiple different adaptors interact with dynein! Work led by @amicoennio.bsky.social. Available now on BioRxiv: doi.org/10.64898/202...

Ennio@amicoennio.bsky.social · 3mo ago

New preprint! We asked a simple question: How do very different activating adaptors all activate dynein? Turns out: same architecture, wildly different implementations 🧵👇 doi.org/10.64898/202...

Congratulations to @lapassmore.bsky.social, Joint Head of the LMB’s Structural Studies Division, who has been elected an international member of @nationalacademies.org Congratulations to #LMBalumni Andrea Brand who has also been elected. Read more: mrclmb.ac.uk/news-events/... #LMBNews

Thrilled with this result, tune in for more soon!

Kai Yi@kaiyi94.bsky.social · 3mo ago

Thrilled with the our results with @kjamali.bsky.social and @sjorsscheres.bsky.social from the recent binder competition! 🎉 2 of our 7 designs successfully bound to the target, with affinities ranking 2nd and 3rd overall. All of these designs targeted the disordered region of the protein.

The early release version of our #cryoEM work on CDK11-cyclin L-SAP30BP has now been published at Nature Communications: www.nature.com/articles/s41... We got very helpful comments from the reviewers and added more structural analysis and biochemistry to support our conclusions. Please have a look!

Basil Greber@bjgreber.bsky.social · 4mo ago

Have a look at our latest results on #CDK regulation, just posted as a pre-print! This study was spearheaded by PhD student Amy McGeoch. Amy has determined the #cryoEM structure of the CDK11-cyclin L-SAP30B complex, an important regulator of #spliceosome activation. www.biorxiv.org/content/10.6...

Congratulations to Manu Hegde, Group Leader & Joint Head of @cellbiol-mrclmb.bsky.social, who has been elected a member of the American Academy of Arts & Sciences. Congratulations also to the #LMBalumni joining him, Julie Ahringer & Edward Egelman. Read more: mrclmb.ac.uk/news-events/... #LMBNews

Very pleased that after a rigorous (and lengthy) review process, our paper visualizing how myosin generated forces modulate actin filament structure for mechanosensitive recogntion by α-catenin has appeared in @nature.com : www.nature.com/articles/s41...

The LMB is proud to launch the Career Returner Fellowship, a three-year, fully funded postdoc placement for scientists who have had a career break of over 1 year. Applications are open now! More details: mrclmb.ac.uk/careers-and-... Please share this post with anyone who may be interested!

I am excited to share our most recent work collaborating with @centriolelab.bsky.social and @stearnslab.bsky.social to look at the ciliary base of mammalian multiciliated cells w/ cryo-ET, XL/MS, and U-ExM www.biorxiv.org/content/10.6...

2nd call for postdoc positions in the lab. Get in touch for more information or simply apply here: mbg.au.dk/en/news-and-...

Postdoc positions in Nuclear RNA Biology - Vacancy at Aarhus University

Vacancy at Department of Molecular Biology and Genetics - RNA Biology and Innovation, Aarhus University

mbg.au.dk