kuba sędziński

@kuba-sedzinski.bsky.social

Studies how to build tissues. Cell developmental biology and biophysics of mucociliary epithelia. Group leader at reNEW, University of Copenhagen. https://renew.ku.dk/research/sedzinski_group/

Beautiful overview on basal body patterning by @raghavan-thiaga.bsky.social and of course please check his latest work on dynamics of basal body patterning in 🐸 multiciliated cells!

epithelial mechanics fan club@epimechfc.bsky.social · last mo.

From single-celled organisms to ciliated epithelia in metazoans, precise positioning of basal bodies (BBs), which anchor motile cilia, is essential for generating fluid flows. Here, I, @raghavan-thiaga.bsky.social, will take you on a brief tour of how cells build this spatial organization.

💥 🚀 New preprint! 🎉🥳 How do hundreds of organelles organize themselves into near-perfect patterns inside a cell, without a blueprint? We dive deep into how basal bodies (BBs) self-organize in MCCs - and how actin actively tunes their dynamics into order 🍪 🧵👇 (1/17)

Are you interested on how regenerating tissues transit between stages? Am sharing here our work showing that during #Xenopus tail regeneration, tissue stiffening activates a Piezo1-Yap1 mechanosensitive cascade to allow wounded epithelia to transit into regenerative states!