Gross, B. J., Soltwedel, J. R., ..., Gomez, C., & Campàs, O. (2025). STRESS, an automated geometrical characterization of deformable particles for in vivo measurements of cell and tissue mechanical stresses. Scientific Reports, 15(1), 28599. #EpithelialMechanics www.nature.com/articles/s41...

www.biorxiv.org/content/10.6... Zyxin and LPP differ in their sensing of strained actin filaments at tricellular junctions

MUC5B and MUC5AC function in combination to regulate mucociliary transport on human airway epithelium https://www.biorxiv.org/content/10.64898/2026.09.08.750178v1

www.biorxiv.org/content/10.6... Ultrastructural dynamics of basal bodies during microgamete formation and fertilisation in Plasmodium

🧵 What if one reason fertility declines with age isn’t just genetic-but mechanical? Thrilled to share our new paper in @NatureCellBio : Elevated contractility drives implantation failure in mouse embryos from aged females… here’s what we found 👇 www.nature.com/articles/s41... 1/11

Elevated contractility drives implantation failure in mouse embryos from aged females - Nature Cell Biology

Cavanaugh et al. show that embryos from aged mice have increased contractility and tissue viscosity on embryonic day 4.5, which leads to poor spreading and attachment. Similar age-associated mechanica...

nature.com

In @jcb.org, Yamaguchi et al. show that cell chirality arises from directional #actin flows driven by class 1 myosins in #Drosophila #macrophages. Myo1D organizes polarized circular F-actin that Myo2 rotates clockwise, providing a molecular basis for cell #chirality. rupress.org/jcb/article/...

PAK4: A vanguard of epithelial vertex remodeling. Raghavan Thiagarajan @raghavan-thiaga.bsky.social and Jakub Sedzinski @kuba-sedzinski.bsky.social @ucph.bsky.social discuss new work by @babliadhikary.bsky.social et al. (rupress.org/jcb/article/...) in Spotlight: rupress.org/jcb/article/...

Happy to share our new paper @natcomms.nature.com on the role of active nematics on myoblast fusion and myotube growth! www.nature.com/articles/s41... Amazinf work from @dubey837.bsky.social, @yoannletoquin.bsky.social and Aleksandra Ardaševa!

Spotlight @jcb.org: @babliadhikary.bsky.social et al. (rupress.org/jcb/article/...) describe the role of PAK4 in vertex remodeling, thereby maintaining epithelial integrity & barrier function. @raghavan-thiaga.bsky.social and @kuba-sedzinski.bsky.social discuss the study: rupress.org/jcb/article/...

Spotlight: @babliadhikary.bsky.social et al. (rupress.org/jcb/article/...) describe the role of PAK4 in vertex remodeling, thereby maintaining epithelial integrity and barrier function. @raghavan-thiaga.bsky.social and @kuba-sedzinski.bsky.social discuss the study: rupress.org/jcb/article/...

Tissue morphogenesis demands massive deformations, yet tissues must stay coherent. This is achieved through cell intercalation, also known as T1 transitions. But what drives them mechanically? I'm @arturruppel.bsky.social, and I'll walk you through the physics, from whole embryos down to four cells

Happy to share our new eLife paper on tissue dynamics during anterior-posterior axis formation. elifesciences.org/reviewed-pre...

Nature research paper: Amygdala astrocyte primary cilium mechanisms contribute to stress behaviours go.nature.com/3UiC3bT

Amygdala astrocyte primary cilium mechanisms contribute to stress behaviours - Nature

Amygdala astrocyte primary cilia are disrupted during stress, and their restoration leads to improvements in stress-related behaviour in mice.

go.nature.com

Cilia alert! Last year Juyeon Hong described a new domain in 9+2 cilia called the EDT, the extreme distal tip. Now, she's found a new protein required for its assembly, but only in non-mammalian vertebrates. A cool evo-cell / protein evolution story in @cellreports.bsky.social tinyurl.com/2xvdskx6

How do tissues safely remove cells? Join me, @marija-matejcic.bsky.social in this perspective on the past, present and future of epithelial cell extrusion 🧵 0/16

New Toettchlab paper alert! Harrison Oatman just published his beautiful work combining software design for "smart" microscopy+optogenetics and some really beautiful work understanding EGFR-driven collective cell migration. www.cell.com/cell-systems...

@babliadhikary.bsky.social, Higashi et al. show that PAK4 drives dynamic vertex remodeling in cells and embryos through spatiotemporal regulation of #myosin II. Inhibition of PAK4 disrupts tissue packing and compromises junctional continuity and barrier function. rupress.org/jcb/article/...

Septins and cytokinesis in the polymorphic fungus Aureobasidium pullulans rupress.org/jcb/article-...

Septins and cytokinesis in the polymorphic fungus Aureobasidium pullulans

Budding yeasts are thought to use septins to mark mother–bud necks as sites for cytokinesis. Here, Colarusso et al. find that the multibudding yeast Aureob

rupress.org

www.biorxiv.org/content/10.6... Sol-gel Transition Drives Hyper-fast Mixing in a Giant Cell super cool work on longstanding question about gel-sol transitions in cells using the giant amoeba Chaos carolinensis! @wallaceucsf.bsky.social

From single-celled organisms to ciliated epithelia in metazoans, precise positioning of basal bodies (BBs), which anchor motile cilia, is essential for generating fluid flows. Here, I, @raghavan-thiaga.bsky.social, will take you on a brief tour of how cells build this spatial organization.

My grad student Oz and I are very excited to share our new work, Differentiable Design for Morphogenesis www.biorxiv.org/content/10.6... (waxMorph)

Dynein-microtubule forces drive nucleokinesis and transmigration in T cells www.biorxiv.org/content/10.6...

📢Check out our latest preprint list on FocalPlane In this list, we focus on the latest tools and techniques in imaging, including sample prep, probes, hardware and software. focalplane.biologists.com/2026/06/26/m... Let us know if you've been reading a preprint that we should add to our list.

Microscopy preprints – new tools and techniques in imaging - FocalPlane

Microscopy preprints – new tools and techniques in imaging - News

focalplane.biologists.com

How do cells adapt morphology to function? In a 🔥 preprint by @zjmaggiexu.bsky.social , with @dudinlab.bsky.social and @amyweeks.bsky.social , we identify a self-organizing single-cell morphology circuit that optimizes the feeding trap structure of the suctorian P. collini. 🧵 tinyurl.com/4k8nv926

Tateishi, K., Nishida, T., Inoue, K., & Tsukita, S. (2017). Three-dimensional organization of layered apical cytoskeletal networks associated with mouse airway tissue development. Scientific reports. #EpithelialMechanics doi.org/10.1038/srep...

Kunimoto, K., Yamazaki, Y., Nishida, T., Shinohara, K., Ishikawa, H., Hasegawa, T., ... & Tsukita, S. (2012). Coordinated ciliary beating requires Odf2-mediated polarization of basal bodies via basal feet. Cell, 148(1), #EpithelialMechanics doi.org/10.1016/j.ce...

Kunimoto, K., Yamazaki, Y., Nishida, T., Shinohara, K., Ishikawa, H., Hasegawa, T., ..., Tsukita, S., & Tsukita, S. (2012). Coordinated ciliary beating requires Odf2-mediated polarization of basal bodies via basal feet. Cell, 148(1-2), 189–200. #EpithelialMechanics doi.org/10.1016/j.ce...

New research from #JRSocInterface: Closed-loop control of the small intestinal transport within an integrated mechano-physiological framework doi.org/10.1098/rsif... | #Biophysics #ChemicalEngineering #ComputationalBiology

Articles in our new #Microtubules collection explore how #kinesins coordinate stepping behavior during transport or generate mechanical stress, as well as mechanisms underlying #dynein activation. New research to accompany @embo.org @embl.org Workshop: 👉 rupress.org/jcb/collecti... #EESMicrotubules