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Ruth Franklin

@ruthfranklinlab.bsky.social

Associate Professor @Harvard Immunology, tissue biology, regeneration Proud mama www.ruthfranklinlab.com

57 Posts726 Follower370 Folgt
Ruth Franklin@ruthfranklinlab.bsky.social · 2mo ago

🎉 New preprint from @aybv.bsky.social, grad student extraordinaire!! He found an unexpected function for IFN-I: priming the lung epithelium for repair! (With some help from our beloved macrophages). Congrats to Alan and the rest of the coauthors!

Alan Y. Baez Vazquez@aybv.bsky.social · 2mo ago

Come check out my FIRST EVER first author paper! Especially if you’re interested in the interplay between host defense and tissue repair! Turns out they might be more closely linked than one might think! 🧐💭

Ruth Franklin@ruthfranklinlab.bsky.social · 7mo ago

🎉🎉🎉 Can’t wait to see the amazing science that is sure to come from the Sullivan lab!!!

Zuri Sullivan@zurisullivan.bsky.social · 7mo ago

Thrilled to start my lab at the @whiteheadinstitute.bsky.social @mit.edu and to join such a special community of creative and inspiring colleagues. The Sullivan Lab asks (1) how and (2) why infections make us sick, bridging immunology and neuroscience to understand host defense at the organism scale

Ivan Zanoni@lozanzi.bsky.social · last yr.

#WeekendRead! #InterferonsFriendsOrFoes?! @ruthfranklinlab.bsky.social, Medzhitov, Hoagland, Rodriguez-Morales &co show @science.org that macrophage-derived oncostatin M overcomes type I IFN detrimental responses during severe influenza lung infection by driving AT-II epithelial cell proliferation!

Macrophage-derived oncostatin M repairs the lung epithelial barrier during inflammatory damage

Tissue repair programs must function alongside antiviral immunity to restore the lung epithelial barrier following infection. We found that macrophage-derived oncostatin M (OSM) counteracted the patho...

science.org

Alan Y. Baez Vazquez@aybv.bsky.social · last yr.

I’m so proud to have been able to contribute to this story! Check it out for a cool tale about tissue repair under inflammatory conditions! Congrats @daisyah.bsky.social and @ruthfranklinlab.bsky.social on putting out the lab’s first paper 🫁🐁🦠 www.science.org/doi/10.1126/...

Macrophage-derived oncostatin M repairs the lung epithelial barrier during inflammatory damage

Tissue repair programs must function alongside antiviral immunity to restore the lung epithelial barrier following infection. We found that macrophage-derived oncostatin M (OSM) counteracted the patho...

science.org

Ruth Franklin@ruthfranklinlab.bsky.social · last yr.

🎉 Over the moon to share the first paper from my lab!! We discovered an unexpected role for the cytokine OSM in lung epithelial homeostasis and repair. 🧵 1/n www.science.org/doi/10.1126/...

Macrophage-derived oncostatin M repairs the lung epithelial barrier during inflammatory damage

Tissue repair programs must function alongside antiviral immunity to restore the lung epithelial barrier following infection. We found that macrophage-derived oncostatin M (OSM) counteracted the patho...

science.org

Jennifer Waters@jencwaters.bsky.social · last yr.

"The money the government sends to Harvard is, in effect, not a subsidy to advance the university’s mission. It’s a payment for the role Harvard plays in advancing the research mission of the United States." www.nytimes.com/interactive/...

Here Is All the Science at Risk in Trump’s Clash With Harvard (Gift Article)

More than 900 research grants worth $2.6 billion are in jeopardy. So is the 80-year-old model of American science.

nytimes.com

Dr. David Miller 🏳️‍🌈@davidimiller.bsky.social · last yr.

🚨 Action alert: Two days left!! Help protect NSF/NIH from political interference. 👎 A new rule (Sched. F) would allow for replacing career program officers with political appointees. ➡️ Action: Object here by THIS FRIDAY. Comments can be brief and/or anonymous. Helps future litigation.

Improving Performance, Accountability and Responsiveness in the Civil Service

The Office of Personnel Management (OPM) is proposing a rule to increase career employee accountability. Agency supervisors report great difficulty removing employees for poor performance or misconduc...

federalregister.gov

Jon Levy@jonlevybu.bsky.social · last yr.

On a day when all research grants at Harvard were terminated, and in a context where Congress seems to broadly accept the notion that destroying science and health research in the US is fine, it’s worth noting that this is not what the public wants.

Jacquelyn Gill@jacquelyngill.bsky.social · last yr.

The American public is broadly supportive of maintaining federal science and medical research funding, and against punishing universities by taking their funding away, according to a new poll:

Shruti Naik@drshrutinaik.bsky.social · last yr.

Misinformation is winning not because it's true, but because it’s loud, emotional, and everywhere. It’s time for science to fight back. Aaron Mertz and I dissect the issue and offer solutions 👇 📖 www.nature.com/articles/s41... #SciComm @sinaiimmuno.bsky.social @aspeninstitute.bsky.social

Beyond the lab: trust, storytelling and the fight for America’s attention - Nature Reviews Immunology

Shruti Naik, an immunologist and a strong advocate for diversity in science, has joined forces with Aaron Mertz, who leads programmes that help to explain, connect and maximize the benefits of science...

nature.com

Ryan Flynn@raflynn5.bsky.social · last yr.

Excited to share the work of Jonathan Perr where he uncovered a surprisingly common feature of cell surfaces - the presentation and clustering of RNA binding proteins with #glycoRNA. Critically support by #NIH @cp-cell.bsky.social www.cell.com/cell/abstrac...

RNA-binding proteins and glycoRNAs form domains on the cell surface for cell-penetrating peptide entry

Mammalian cells present RNA-binding proteins on the cell surface that form clustered domains containing glycoRNAs.

cell.com