Happy to share our latest study by Annesha Ghosh, published in PLOS Pathogens. Our work shows that disruption of RNA cap methylation can act as a danger signal to activate protective innate immunity. dx.plos.org/10.1371/jour...
RNA methyltransferase CMTR-1 inhibition activates a GATA transcription factor-mediated protective immune response
Author summary The immune system is commonly thought to defend the body by recognizing invading microbes. However, organisms can also detect infections indirectly by sensing damage to their own cellul...
dx.plos.org