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Manuel Mendoza

@longchrom.bsky.social

Nuclear pore complexes and RNA export, Chromosomes and cytokinesis @igbmc.bsky.social Strasbourg. Who took the Bomp from the Bompalompalomp? Who took the Ram from the Ramalamading-dong? 🇻🇪 🇪🇸 🇫🇷

202 Posts455 Follower524 Folgt
Matthew Taliaferro@jmtali.bsky.social · last wk.

Excited to share our newest work! We asked whether RNA molecules need to be in a specific place in the cell to do their job. We found that a single RNA must reach the midbody, the structure that pinches two dividing cells apart, for cell division to finish efficiently. 🧵⬇️

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c0nc0rdance@c0nc0rdance.bsky.social · 2w ago

I've finally found it. The most painful science montage in movie history. Mega Shark Versus Giant Octopus (2009) Yes, Gen X, that is singer Debbie Gibson as oceanographer 'Emma MacNeil'. But the important thing is: she's keeping an accurate lab notebook.

Angela Andersen@angelaandersen.bsky.social · 3w ago

Kudos to @science.org for this self-analysis of the peer review process. These kind of data are never shared and don't have to be. Wildly refreshing to see it out in the open. Editorial and peer review dynamics at elite general science journals | Science Advances www.science.org/doi/10.1126/...

Editorial and peer review dynamics at elite general science journals

Analyses of deidentified data reveal complex interactions that quantify success at elite general science journals.

science.org

Posas Lab@posaslab.bsky.social · 3w ago

We're looking for a highly motivated Postdoctoral Fellow (Ref. PD/26/11) to join our team at @irbbarcelona.org to study MAPK signaling & conserved stress adaptation mechanisms, using cutting-edge transcriptomics, genomics & proteomics. Apply here: recruitment.irbbarcelona.org/jobs/8135937...

Postdoctoral Fellow (Ref. PD/26/11) - IRB Barcelona

Your Role & Our Team IRB Barcelona is seeking a highly motivated and talented Postdoctoral Fellow to participate in cutting edge research line -Crosstalk analysis of MAPK signaling- of the ...

recruitment.irbbarcelona.org

Joseph Schacherer@schacherer.bsky.social · 3w ago

Excited to share this personal story published by @GeneticsGSA. A reflection on my journey in genetics, the many people who shaped it, the @haploteam and my enduring fascination with diversity. Thanks to everyone who has been part of the adventure! academic.oup.com/genetics/adv...

The genetics of the many forms of diversity

Abstract. The Genetics Society of America Medal honors an individual member of the Society for their contributions to the field of genetics at the midcaree

academic.oup.com

Stirling Churchman@stirlingchurchman.bsky.social · 4w ago

RNA-seq tells us how much RNA is present in the cell. But to understand gene regulation, we need to easily measure the synthesis and decay rates driving this abundance. We introduce AIR-seq: analog intrinsic recoding sequencing. (1/6) www.biorxiv.org/content/10.6...

Analog intrinsic recoding measures RNA dynamics without chemical conversion

Steady-state RNA abundance measurements mask the synthesis and decay rates that shape gene expression. Analog intrinsic recoding sequencing (AIR-seq) repurposes the base-pairing properties of N4-hydro...

biorxiv.org

Nature Structural & Molecular Biology@natsmb.nature.com · 3w ago

New online: A protective ESCRT sleeve for ultrafine DNA bridges

A protective ESCRT sleeve for ultrafine DNA bridges

Nature Structural & Molecular Biology, Published online: 29 July 2026; doi:10.1038/s41594-026-01856-xDNA bridges, thin DNA connections that link daughter cells after division, threaten genome integrity and can trigger catastrophic chromosome rearrangements. A new study proposes that ESCRT-III proteins form protective assemblies around fragile ultrafine DNA bridges, revealing an unexpected role for these membrane-remodeling complexes in genome protection.

dlvr.it

Christophe 🔬 Leterrier@christlet.bsky.social · 4w ago

Always a pleasure to have given multiple hours to help as a member of a thesis advisory committee and to casually find out that the thesis was defended and deposited, without even an email about it from the student or the mentors… The kind of things people can only do once as far as I'm concerned

Hank Greely@hankgreely.bsky.social · 4w ago

Great, detailed story on a death in a tragic & flawed Chinese gene therapy trial www.science.org/content/arti... Excellent job by Brendan Borrell w/ @retractionwatch.com. Complex, nuanced & in some respects damning. (On line version looks a bit longer than in Science.) (COI-quotes me, in passing).

Exclusive: Death of girl in Chinese gene-editing trial was never made public

Parents want accountability after study went disastrously wrong, Science and Retraction Watch investigation reveals

science.org

Raphaël Pantier@r-pantier.bsky.social · last mo.

Our laboratory is looking for a PhD student in Functional Genomics (fully funded position). Expected starting date: Oct 2026 More info here: www.igbmc.fr/en/igbmc/lif... Please share 📨

IGBMC: PhD position available in Raphaël Pantier's lab

igbmc.fr

IGBMC@igbmc.bsky.social · last mo.

PhD position in Functional Genomics, in Raphaël Pantier's lab: Interplay between transcription factors and genome architecture in embryonic stem cells more info : amethis3.unistra.fr/amethis-clie...

Wes Cowley@wes.wordsbywes.ink · last mo.

That quote links to articles on AlphaFold (and variants) and GNoME, neither of which are large language models. AlphaFold shares some concepts with LLMs (attention and transformers); GNoME not so much. (2/7)

Juan Martin Serrano@juanmartin-serrano.bsky.social · last mo.

ESCRTs are repurposed when missegregated DNA persist during nuclear envelope reformation, at this point ESCRT-III binds this DNA and mounts the NoCut response to protect the genome

Juan Martin Serrano@juanmartin-serrano.bsky.social · last mo.

Very proud to see this paper out. This is an incredible collaboration with the labs of Wes Sundquist and Adam Frost. @uofubiochem.bsky.social @kingslsm.bsky.social www.nature.com/articles/s41...