Nature research paper: HIV-1 signalling remodels nuclear pores to licence infection go.nature.com/49hjtFQ

HIV-1 signalling remodels nuclear pores to licence infection - Nature

HIV-1 capsid nuclear import at the nuclear pore complex is a bottleneck to resting T cell infection, but HIV-1 overcomes this by triggering receptor-mediated signalling during cell–cell spread to drive nuclear import and licence infection.

go.nature.com

Nature Baby! So proud to share below, a story led by myself and the legend @d-mesner.bsky.social + senior-author @jollylab.bsky.social in @nature.com This work excitingly answers many of the key research questions from my @wellcometrust.bsky.social Early Career award! And opens new horizons!

Jolly Lab@jollylab.bsky.social · 3mo ago

We are incredibly excited to see our most recent story out @nature.com today:HIV triggers CD4-signaling to remodel nuclear pores and license infection!A heroic effort led by our very own @d-mesner.bsky.social & @mattvxwhelan.bsky.social! @blizardinstitute.bsky.social Link: tinyurl.com/HIVNup 1/11

Really excited to be awarded a British council UK-Germany Springboard grant! Exciting times ahead as a UK cohort featuring the labs of myself and Ines Castro and @jollylab.bsky.social will launch trips and research meetings to build a collaboration with @marinalusic.bsky.social in CIID Heidelberg.

I was invited by @focalplane.bsky.social to write a short description about it: focalplane.biologists.com/2025/12/12/a...

A new version of TrackMate with improved integration of key AI algorithms and track edition improvements - FocalPlane

A new version of TrackMate with improved integration of key AI algorithms and track edition improvements -

focalplane.biologists.com

Jean-Yves Tinevez@jytinevez.bsky.social · 8mo ago

The new version of TrackMate, the v8.1 has just been released. It builds upon the recent v8, linked below, and offers two main improvements 👇

Really enjoying #EESNucleus day one! Great to be back in @embl.org

Starting today: @events.embl.org #EESNucleus Make sure to say Hi to our editor @hvodermaier.bsky.social and discuss your latest work with him!

Hartmut Vodermaier@hvodermaier.bsky.social · 9mo ago

As my conference year draws to a close: still one last highlight coming up #EESNucleus on home turf @events.embl.org!

📢 Join us next week for our mini-symposium with the membrane trafficking webinar series Featuring talks from @nickader.bsky.social, @maiblab.bsky.social and Mónica Quiñones-Frías, and a keynote lecture from Gillian Griffiths @griffithslab.bsky.social.

FocalPlane features... membrane trafficking - FocalPlane

FocalPlane features... membrane trafficking - News

focalplane.biologists.com

Great to see this in the wild!

Kate Morling@katemorling.bsky.social · 11mo ago

Excited to share the preprint for our work on cyclosporine-based lentiviral transduction enhancer, BG147, which degrades innate immune barrier IFITM3, increasing gene delivery in gene therapy. Huge thanks to everyone involved! @towerslab.bsky.social www.biorxiv.org/content/10.1...

Call for papers: Cell Biology of the Nucleus We invite you to submit your latest research to our special issue: Cell Biology of the Nucleus, guest edited by Abby Buchwalter @abbybuch.bsky.social, working alongside Megan King @luskinglab.bsky.social. journals.biologists.com/jcs/pages/nu...

I'll be there!

Gautam Dey@gautamdey.bsky.social · last yr.

1 month to abstract deadline for the first cell biology of the nucleus meeting at @embl.org in many years - organised by the stellar @luskinglab.bsky.social @sarawickstrom.bsky.social Tom Quail & Simone Koehler Tons of open slots, invited and selected speakers all get 20 mins ❤️ #EESNucleus

Really excited to be back in my home away from home, Berlin, for my first conference in Germany: "Life at the Edge: The nuclear envelope in nucleocytoplasmic transport and genome organisation" Really looking forward to it!

Come work at Nature Methods! A dream job. I know from experience 😄

Nature Methods@natmethods.nature.com · last yr.

Nature Methods is hiring! We are seeking a new editor with expertise in microscopy, imaging technology, and/or cell biology. The position is available in NYC/Jersey City or Shanghai/Beijing on a hybrid working model. Apply by August 3! springernature.wd3.myworkdayjobs.com/SpringerNatu...

Hyped to be moving to the Blizard Institute @qmul.bsky.social in the Autumn. As part of an exciting new development in infection research within the Blizard, I’ll be a Group Leader, Academic Lead of the Blizard Advanced Light Microscopy (BALM) Facility and soon take up a Senior Lectureship.

Towers Lab@towerslab.bsky.social · last yr.

We are delighted to be joining the Blizard Institute in Autumn. The Blizard Institute is an amazing place for discovery science and we're looking forward to more transformative research and collaborations. www.qmul.ac.uk/blizard/abou...

Hugely excited to work with this!

Ricardo Henriques@henriqueslab.bsky.social · last yr.

It's here! ✨ The #ExSRRF protocol paper is out 😍. Full details for merging Expansion Microscopy with our eSRRF analysis. From cells to tissue. A partnership with @puellesv.bsky.social's lab. Lead by Dominik Kylies and @hannah-superres.bsky.social + colleagues. #ExM #eSRRF ➡️ Open link: rdcu.be/euvEw

This was a lot of fun! Great to be back in my Alma Mater.

Siobhán McClean@siobhanmcclean.bsky.social · last yr.

🧪Great talk by @mattvxwhelan.bsky.social in the @ucddublin.bsky.social Conway CLASS lecture. Amazing images of HIV / Nuclear interactions

Great to see this out! And very fitting the last publication from my PhD is in a @microbiologysociety.org journal. Who played a significant role in supporting my EARLY early career!

Tadhg O Croinin@tadhgocroinin.bsky.social · last yr.

New paper from @mattvxwhelan.bsky.social from his PhD looking at Campylobacter invasion of intestinal spheroids and published in Microbiology. Remember supporting our society's journals ensures they can continue to support us!! @microbiologysociety.org www.microbiologyresearch.org/content/jour...

I cannot believe I didn't post about dark sectioning! I can only blame my crazy travel schedule. Check out this amazing tool for background removal in fluorescence microscopy. An important new concept, not 'just another' denoising algorithm.

@xipeng1.bsky.social · last yr.

Our groundbreaking Dark Sectioning technique is now published in Nature Methods! 🎉 It supercharges existing imaging systems: 🔬 Widefield → Confocal 🔬 Single-photon → Multiphoton 🔬 2D-SIM → 3D-SIM Now integrated in Airy PolarSIM and #FlexSIM! doi.org/10.1038/s415... #Microscopy #Fluorescence

Really great talk by @melghazaly.bsky.social from @towerslab.bsky.social in #CSH #Retroviruses !

Yesterday, @mattvxwhelan.bsky.social gave a fantastic talk! Thanks for all the engaging questions and all the great science chat afterwards! #cshretro

It was a huge honour to speak today in the beautiful locale of Cold Spring Harbor, Long Island, NY. At an epic post entry events session on the 50th anniversary of #CSH #Retroviruses

Can't wait for this!

Journal of Cell Science@jcellsci.bsky.social · last yr.

After the success of our 2023 Imaging Cell Dynamics conference, we’ll be hosting a second #JCSImaging meeting in 2026, organised by @franbottanelli.bsky.social, @guijacquemet.bsky.social‬, @drmichaelway.bsky.social‬ & Giulia Zanetti. To register your interest: www.biologists.com/meetings/jcs...

Our latest preprint list is now up on FocalPlane. Our list this week is focusses on research using 🔬microscopy tools to answer questions in biology. As always, please let us know if there are other preprints that you’d like to see included. focalplane.biologists.com/2025/05/16/m...

Microscopy preprints - applications in biology - FocalPlane

Microscopy preprints - applications in biology - News

focalplane.biologists.com

Join us at Virtual Virology for an afternoon of excellent science!

RM@rsbmilne.bsky.social · last yr.

Virtual Virology is back - our first ever phage session. Do join us...

🖱️ Picking out individual cells in distorted microscopy images is now as easy as clicking a button, thanks to Cellpose3: www.janelia.org/news/newest-...

Newest version of Cellpose can spot cell boundaries even in cloudy conditions

Picking out individual cells in distorted microscopy images is now as easy as clicking a button. A new version of Cellpose – the popular tool that maps the boundaries of diverse cells in microscopy

janelia.org

A computational framework links transcriptomic analyses with mechanical signatures to study the interplay between cell mechanical forces and gene expression. www.nature.com/articles/s41...

We are #hiring! We have two open postdoc/research scientist positions to join our #ERC funded project MITOFOLD to resolve the organization of mitotic chromosomes! 1) experimental biologist shorturl.at/LjGEM 2) data scientist shorturl.at/nDdhQ Please share! 🙌 We look forward to your application! 🤩

Do you LOVE organelles?? Well I am THRILLED to announce that Nellie has been published in @naturemethods.bsky.social! Nellie a fully automated pipeline for organelle segmentation, tracking, and hierarchical feature extraction in 2D, 3D, timelapse, multichannel live-cell microscopy 🧵1/N

[Phys.Org]A completely new type of microscopy based on quantum sensors - Phys.org Researchers at the Technical University of Munich (TUM) have invented an entirely new field of microscopy called nuclear spin microscopy. The team can visualize magnetic signals of nuclear magnetic resonance with a...

We wrote a protocol to quantify plasma membrane fluidity using a confocal microscope 🔬 Hopefully those interested in measuring membrane biophysical properties in live cells find it useful. We also provide an ImageJ/Fiji tool to make the analysis as easy as possible. www.nature.com/articles/s41...

Measuring plasma membrane fluidity using confocal microscopy - Nature Protocols

Membrane fluidity is a crucial feature in understanding cellular physiology. This protocol describes a robust pipeline for measuring plasma membrane fluidity using confocal imaging and new environment...

nature.com

Bring your samples into focus! A new version of the #Cellpose cell boundary mapping tool, developed at @hhmijanelia.bsky.social by @computingnature.bsky.social and @marius10p.bsky.social, now works on less-than-perfect microscopy images that are noisy, blurry, or undersampled.

Newest version of Cellpose can spot cell boundaries even in cloudy conditions

Picking out individual cells in distorted microscopy images is now as easy as clicking a button. A new version of Cellpose – the popular tool that maps the boundaries of diverse cells in microscopy

buff.ly