🧠 HIRING: Tenure-Track Faculty in Translational Neuroscience 🧬 @uksbcoa.bsky.social seeks collaborative investigators focused on ADRD. Areas of interest neuroinflammation, cerebrovascular disease, biomarkers, omics, iPSC models, behavioral science & more✨ Apply: ukjobs.uky.edu/postings/604...

Researcher - Translational Neuroscientist

The Sanders-Brown Center on Aging (https://medicine.uky.edu/centers/sbcoa) at the University of Kentucky College of Medicine is seeking outstanding PhD, MD, or MD/PhD scientists to fill a regular titl...

ukjobs.uky.edu

🚨Fresh pre-print collab with @johnsonlab.bsky.social, Norton Healthcare, and our @uksbcoa.bsky.social collaborators. We report a coordinated CD8+ Tcell immunometabolic program associated with amyloid-related imaging abnormalities (ARIA) during lecanemab therapy👇 🔗 www.medrxiv.org/content/10.1...

Clonal expansion of cytotoxic CD8⁺ T cells in lecanemab-associated ARIA

Amyloid related imaging abnormalities (ARIA) remain the principal safety concern limiting adoption of anti amyloid therapies such as lecanemab, yet their underlying biology is poorly defined. To addre...

medrxiv.org

New pre-print out: www.biorxiv.org/content/10.1... Surprise surprise 🤗, microglia proximity to AD pathology alters their immunometabolic signatures Excellent work by Kai Saito and our team, along with our awesome collaborators Pete Nelson, @macauleylab.bsky.social, @johnsonlab.bsky.social

High-Resolution Spatial Profiling of Microglia Reveals Proximity Associated Immunometabolic Reprogramming in Alzheimers Disease

Single-cell RNA sequencing has demonstrated that the presence of parenchymal amyloid plaques and intracellular hyperphosphorylated tau pathology is associated with distinctive (and possibly disease-dr...

biorxiv.org

new preprint! www.biorxiv.org/content/10.1... a characterization of APOE effects on the lipid droplet-ome (turns out you see a lot of "AD-related" proteins!) first authors Cassi Friday & Isaiah Stephens + great collaborators Scott Gordon, @cohenlaboratory.bsky.social @morganti.bsky.social

Join us!

go.bsky.app/Lyzro3M !WELCOME! thought we might need a starter pack for all those coming over from the birdhouse - here's a GliaSky list. apologies for missing many of you - please do reply to get added and remember to repost so the newbies can find us!

Any of my #APOE buddies here yet? Abstract submissions are open for AAIC Advancements: APOE and #Lipid Biology, March 17-18, 2025 in Miami www.alz.org/apoe/overvie...

AAIC Advancements: APOE & Lipid Biology | alz.org

Neuroscience researchers should attend this Alzheimer's Association conference to discuss the role of APOE & lipid biology in neurodegenerative diseases.

alz.org