Nathalie Percie du Sert

@nathalie-pds.bsky.social

Director of Research Practice @nc3rs.bsky.social

Developed in direct response to NC3Rs recommendations, new guidance from the World Health Organisation (@who.int) encourages manufacturers and regulators to replace or remove animal-based quality control methods for vaccines and biologics: nc3rs.org.uk/news/new-who...

New WHO guidelines on non-animal tests for quality control of biologics

Developed in direct response to NC3Rs recommendations, new guidance supports manufacturers and regulators to transition to non-animal testing strategies.

nc3rs.org.uk

Great to see this publication optimising a hydrogel-based model of cartilage. This approach has the potential to become a scalable platform to investigate biomechanical responses and replace mice in studies of musculoskeletal disease progression and ageing. Learn more: nc3rs.org.uk/our-portfoli...

Kasia Pirog@kasiapirog.bsky.social · last yr.

Our new paper is out! Well done Marc, Thais, Fran et al @cgm-newcastle.bsky.social! And thank you to @nc3rs.bsky.social and the #JGWPattersonFoundation for funding and support. analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...

SURVEY: New approach methodologies in safety assessment Are you involved in the development and application of replacement technologies for toxicity testing or submission and assessment of data for regulatory decision making? Help shape our plans for the coming years: nc3rs.org.uk/our-portfoli...

Icons representing new approach methodologies and chemical and drug safety testing, in a speech bubble.

The EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) have joined two of our CRACK IT projects as Challenge Partners, bringing their experience in validating new approach methodologies to help bridge the gap between innovation and market adoption: nc3rs.org.uk/news/eurl-ec...

A quote from Professor Maurice Whelan, Head of EURL ECVAM: “Our longstanding collaboration with the NC3Rs is very important to us and we’ve always been great admirers of CRACK IT. The challenge-led format really fosters solution-driven 3Rs innovation and ensures very tight collaboration between developers and end-users. We’re delighted now to have the opportunity to get involved, to support where we can and to learn from the experience.”

Register for our NAMs Network symposium to connect with developers and end-users of new approach methodologies and join the discussion about reducing the reliance on animals for toxicity testing. 🗓️ Thursday 1 May, 9.30 – 17.00 📍 London, UK 👉 nc3rs.org.uk/events/nc3rs...

Icons representing new approach methodologies to replace animal use for assessing chemical or drug toxicity - a lab flask, a molecule structure on a computer screen and an environmental scene.

A friend included this anti-acknowledgement section on her PhD thesis. She also added the proposition: “Systematic bullying and undermining of girls and women in STEM starts early on and is the reason why they do not stay in science and related fields.” Absurd we still need to go through this 🧪👩‍🔬

There have been people less than helpful in my journey here. I wanted to acknowledge those too, bc I know I am not unique in this experience.
No thank you to the physics study assoc that made me sing songs about how women couldn't study physics without sleeping with the professor, the day I stepped into university life. No thank you to the 5th year physics student that decided to assign me a stripper name within the first minute of meeting me in the physics coffee corner in my first year. No thank you to the technician that was responsible for onboarding me on the use of the cluster in my third year who raised his eyebrows and asked me if that meant I was some sort of computer girl. No thank you to the senior researcher that sent me utterly inappropriate texts after a conference, then proceeded to apologise months later by telling me they had not been meant for me anyway so no hard feelings remain hopefully And no thank you to him for attending every conference I've been to since. No thank you to the people who told me that it was surprising that I was doing a PhD since I was a girl. No thank you to the man who mistook me for a coffee lady at a conference, and after having to correct him two times that I did not work there, responded with you should consider it. No thank you to the researcher that asked me what I was wearing underneath my outfit during a conference. No thank you to the physicist who declared to a room full of other physicists that biologists don't know how to design an experiment. No thank you to the people who have called me scary instead of strong and intimidating instead of intelligent.
And finally, no thank you to the exec board of the TU Delft, whose knee-jerk reaction to being held up a mirror about the social safety at the university, was to sue the party holding up the mirror instead of looking at the problems they highlighted.
... You have made me feel like I do not belong in science & I cannot forgive you for that.

dnschecker.org#A/pubmed.ncb... They're removing it from DNS. You can currently get to it using the IP address 34.107.134.59 (add it to your hosts file or local DNS server), but like with USAID it's probably just a matter of time until it's gone unless they're forced to restore it. #pubmed

DNS Checker - DNS Check Propagation Tool

Check DNS Propagation worldwide. DNS Checker provides name server propagation check instantly. Changed nameservers so do a DNS lookup and check if DNS and nameservers have propagated.

dnschecker.org

Pubmed is currently still working for me but not sure how long this will hold. Here is @hildabast.bsky.social ‘s blog post on what to do if Pubmed becomes unreliable absolutelymaybe.plos.org/2025/02/14/w...

What if We Can't Rely on PubMed? - Absolutely Maybe

PubMed is incredibly reliable. And a lot depends on it. It’s an ecosystem built around MEDLINE, the steady feed of new publications…

absolutelymaybe.plos.org

Stefan Marciniak@profmarciniak.bsky.social · last yr.

#Pubmed problems being reported Please say if it’s working for you, your country and search engine (perhaps retweet for larger sample size 🤷‍♂️ fine for me, UK & Safari

THREAD Things that didn't make the news that will likely change our lives for the better The news is not an accurate reflection of the world. Good news doesn't get reported as much. Here are the wonderful things researchers have achieved recently. 1/24

Sunrise over the Tyrol alps

It will be alright in the end. And if it's not alright, it is not yet the end. 

#AcademicSky #ClimateSky #Altmetrics

If your research focuses on infection or immunity join us in two weeks to stay updated on non-animal approaches in the field, including organoids, human cell-based assays and virtual twins. 🦠 Register for the webinar: nc3rs.org.uk/events/non-a... 📅 Wednesday 26 February, 13.00 (GMT)/14.00 (CET)

The Togeth3R Consortium logo and an icon of an immune cell. Text reads: The Togeth3R Consortium presents non-animal approaches in infection and immunity webinar, Wednesday 26 February.

#LoveMethods25 is coming in two weeks. 🔬 Love Methods Week 2025 – Putting Methods like #RRID in the Spotlight! ❤️ ✅ Document your methods with precision – to maximize reusability, transparency, and visibility ➡ Choose from 17 different session and register here: www.bihealth.org/de/aktuell/l...

Love Methods Week - Aktuelles - BIH at Charité

In dieser Woche werden mehrere Workshops und Seminare rund um das Thema Reproduzierbarkeit von Methoden angeboten. (In Englisch)

bihealth.org

⏰ The CRACK IT open call for 3Rs Challenges closes on Monday 10 February. If your organisation is facing a scientific or research challenge that could be solved with a 3Rs approach, get in touch to discuss and submit your idea to sponsor a Challenge. 💡 Find out more: nc3rs.org.uk/crackit/news...

Megaphone icon with text 'Open call for 3Rs Challenges'.