🌍 Working with @gavi.org, @lshtm.bsky.social researchers led by @drjohnellis.bsky.social modelled the potential impact of new TB vaccines across 73 LMICs. 💉 vaccines delivered between 2030 and 2050 could avert up to 61 million TB cases and 7 million deaths by 2100. Read more 👉 bit.ly/4rkkTax

For more than a century, the world has relied on a single licensed TB vaccine. Next generation vaccines, expected from 2029, could help save an estimated 7.3 million lives and generate up to US$135 billion in economic benefits for low- and middle-income countries by 2050: bit.ly/4cHSJQL

New paper from @plosglobalpublichealth.org: which TB screening strategies are the best value as funding shrinks? Modelling clinic/community approaches in 🇿🇦, we found combining strategies reaching risk groups is more cost-effective than any one approach alone doi.org/10.1371/journal.pgph.0006738

Projected population level impact and cost-effectiveness of clinic and community-based tuberculosis screening approaches

The South African National Department of Health have set ambitious targets to scale up TB testing, focusing primarily on clinic attendees. In the context of declining funding for TB care and preventio...

doi.org

New preprint suggests that combining clinic and community-based approaches is key to maximising the cost-effectiveness of #tuberculosis active case finding in South Africa 🇿🇦 Read more 👉 www.medrxiv.org/content/10.6...

Projected population level impact and cost-effectiveness of clinic and community-based tuberculosis screening approaches

The South Africa National Department of Health have set ambitious targets to scale up TB testing, focusing primarily on clinic attendees. In the context of declining funding for TB care and prevention...

medrxiv.org

It's been 10 years since we published our first review of sex differences in #TB prevalence. In this update, we found men remain twice as likely as women to have TB, and disparities have likely widened over time. journals.plos.org/plosmedicine...

Peter MacPherson@petermacp.bsky.social · 5mo ago

We updated our review of sex diff. in #TB prevalence In 102 surveys (4.7M participants) men were 2x as likely to have TB than women Evidence consistent with sex differences widening over time 🧪🛟 journals.plos.org/plosmedicine... @nswartwood.bsky.social @kchorton.bsky.social @uofgshw.bsky.social

🗞️ Recent study with @lshtm-tbmod.bsky.social modelled the potential impact of funding cuts to TB #PublicHealth initiatives from international donors Already implemented USAID cuts could cost $7.5 billion (USD) for healthcare systems & people living with TB Read 🔽 www.lshtm.ac.uk/research/cen...

Our recent modelling study found that the estimated impact of new TB vaccines depends on the efficacy to prevent infectious asymptomatic TB. Read more in our paper out now in @plosmedicine.org! journals.plos.org/plosmedicine...

Estimating the population impact of new tuberculosis vaccines depending on efficacy against infectious asymptomatic tuberculosis: A modelling study

Hira Tanvir and colleagues estimate the potential impact of new tuberculosis vaccines under three scenarios of efficacy and conclude that to achieve the greatest impact, vaccines must prevent asymptom...

journals.plos.org

In this modeling study, Allison Portnoy and colleagues investigate the potential impact of reduced international donor funding on the household economic burden of tuberculosis in low- and middle-income countries 🧪 #MedSky #TB plos.io/4ryyBFX

The potential impact of reduced international donor funding on the household economic burden of tuberculosis in low- and middle-income countries: A modeling study

In a modelling study, Allison Portnoy and colleagues investigate the potential impact of reduced international donor funding on the household economic burden of Tuberculosis in low- and middle-income ...

plos.io

1/📢 In our new publication, we estimate that in 2022, 134 million people worldwide had a recent Mycobacterium tuberculosis (Mtb) infection and were at high risk of progressing to TB disease. Read the full paper in PLOS Medicine (tinyurl.com/mtbinfection). #TBSky

Estimating the global burden of viable Mycobacterium tuberculosis infection: A mathematical modelling study

Alvaro Schwalb and colleagues conducted a mathematical modelling study to estimate the global burden of viable Mycobacterium tuberculosis--that which can cause disease and be transmitted--to help guid...

tinyurl.com

In this mathematical modeling study, Alvaro Schwalb and colleagues estimate the global burden of viable Mycobacterium tuberculosis—that which can cause disease and be transmitted—to help guide disease prevention efforts 🧪 #tuberculosis #MedSky plos.io/4aqzIQV

Estimating the global burden of viable Mycobacterium tuberculosis infection: A mathematical modelling study

Alvaro Schwalb and colleagues conducted a mathematical modelling study to estimate the global burden of viable Mycobacterium tuberculosis--that which can cause disease and be transmitted--to help guid...

plos.io

Our new paper on strategies for implementing a potential new #TB #vaccine in South Africa is now published in @plosglobalpublichealth.org! doi.org/10.1371/jour...

Insights on the implementation strategies for a potential new tuberculosis vaccine in South Africa

Several tuberculosis (TB) vaccines intended for adults and adolescents are in late-stage clinical trials, but there is limited research into how a new TB vaccine would be introduced. South Africa is a...

doi.org

Another successful "Intro to TB Modelling" course in Copenhagen at #WLHC2025. Over 70 joined to learn about TB modelling! Followed by the now-traditional TB Modelling and Analysis Consortium social, which was also very well-attended and a lot of fun.

Our framework that informed the @who.int TB & climate change policy brief out now in @lancetrespirmed.bsky.social, exploring the intersections and implications of climate change for the TB epidemic. Key message? TB should be considered a climate-sensitive disease www.thelancet.com/journals/lan...

Climate change and tuberculosis: an analytical framework

Climate change is likely to exacerbate a range of determinants that drive tuberculosis, the world's leading cause of death from a single infectious agent. However, tuberculosis is often neglected in w...

thelancet.com

New preprint, by myself and Roy Anderson, looking at what impact including PSAC in MDA for schistosomiasis will have and how much it could vary between communities.

medRxivpreprint@medrxivpreprint.bsky.social · 2y ago

Pre-school Age Participation in Mass Drug Administration: Analysing the Impact on Community-wide Schistosomiasis Control https://www.medrxiv.org/content/10.1101/2025.03.06.25323487v1